Homoserine O-acetyltransferase

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homoserine O-acetyltransferase
Identifiers
EC no. 2.3.1.31
CAS no. 9030-72-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, a homoserine O-acetyltransferase (EC 2.3.1.31) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + L-homoserine CoA + O-acetyl-L-homoserine

Thus, the two substrates of this enzyme are acetyl-CoA and L-homoserine, whereas its two products are CoA and O-acetyl-L-homoserine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:L-homoserine O-acetyltransferase. Other names in common use include homoserine acetyltransferase, homoserine transacetylase, homoserine-O-transacetylase, and L-homoserine O-acetyltransferase. This enzyme participates in methionine metabolism and sulfur metabolism.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2B61.

Related Research Articles

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<span class="mw-page-title-main">Cys/Met metabolism PLP-dependent enzyme family</span>

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References