Hyoscyamus muticus

Last updated

Hyoscyamus muticus
Hyoscyamus muticus 01.JPG
Scientific classification OOjs UI icon edit-ltr.svg
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Asterids
Order: Solanales
Family: Solanaceae
Genus: Hyoscyamus
Species:
H. muticus
Binomial name
Hyoscyamus muticus
L.
Synonyms

Hyoscyamus falezlez

Hyoscyamus muticus, the Egyptian henbane, is a shrub in the family of Solanaceae that is native to desert areas of North Africa. It contains alkaloids that are useful in pharmaceuticals. It is used locally as a painkiller and a recreational drug. In high dosages it can be fatal.

Contents

General

Hyoscyamus muticus, commonly known as Egyptian henbane, is native to Sub-Saharan Africa from Mauritania to Sudan and is also found in Saudi Arabia and the eastern Mediterranean. It grows in arid rocky localities, wadis and plains. The wild plants are used in traditional local medicine. It is sometimes cultivated in countries such as Egypt, Pakistan and India for its medicinal alkaloids, which may be exported to countries such as Germany. [1] Ernest Ayscoghe Floyer (1852–1903) successfully cultivated Hyoscyamus muticus to obtain the alkaloid hyoscyamine. [2]

Description

Egyptian henbane is a perennial herb or shrub with a height of up to 1.5 metres (4 ft 11 in). [1] It is a stout succulent, with long stems that have many branches in their upper parts. The lower leaves are broad, while the upper leaves are narrower. The flowers are formed in dense inflorescences up to 30 centimetres (12 in) long. They have white or green corolla and upper lips in deep purple-violet. The fruit is a capsule. [3]

Medical effects

The leaves are high in alkaloids including scopolamine, which is used in pharmaceuticals. When released slowly, scopolamine reduces the nausea of motion sickness or post-operative recovery. In eye drops it dilates the pupils and paralyzes the focusing muscles, which is useful in optical surgery. [4] The roasted seeds are used to make an intoxicating drink, and the leaves are smoked for their intoxicating effect, and to relieve the symptoms of asthma. The leaves may also be applied as a poultice to relieve pain. [1]

The plant is toxic in higher doses, and deaths have been reported from eating locusts that had eaten Egyptian henbane. The Tuareg people use it as a fish poison. [1] An overdose causes symptoms such as an extremely dry throat, constipation, a rapid pulse, blurred vision, excitement, hallucinations, delirium and death. The wives of the Roman emperors Augustus and Claudius used the plant as a poison to eliminate rivals. [4] In February 1881 the survivors of the Flatters Expedition were approached by a group of Tuaregs who sold them milk, meat and dates at a high price. The dates turned out to be poisoned with a substance that caused dizziness and psychosis. [5] This came from the plant called Falezlez by the Tuaregs and El Bettina by the Arabs (Hyoscyamus falezlez). [6] The effect was to induce a burning sensation in the victims' lungs, and to cause them to rush about madly and fire off their guns. [7]

Related Research Articles

<i>Datura</i> Genus of poisonous, potentially psychoactive plants

Datura is a genus of nine species of highly poisonous, vespertine-flowering plants belonging to the nightshade family (Solanaceae). They are commonly known as thornapples or jimsonweeds, but are also known as devil's trumpets. Other English common names include moonflower, devil's weed, and hell's bells. All species of Datura are extremely poisonous and psychoactive, especially their seeds and flowers, which can cause respiratory depression, arrhythmias, fever, delirium, hallucinations, anticholinergic syndrome, psychosis, and death if taken internally.

<span class="mw-page-title-main">Scopolamine</span> Tropane alkaloid & anticholinergic drug

Scopolamine, also known as hyoscine, or Devil's Breath, is a natural or synthetically produced tropane alkaloid and anticholinergic drug that is used as a medication to treat motion sickness and postoperative nausea and vomiting. It is also sometimes used before surgery to decrease saliva. When used by injection, effects begin after about 20 minutes and last for up to 8 hours. It may also be used orally and as a transdermal patch since it has been long known to have transdermal bioavailability.

<i>Datura stramonium</i> Species of flowering plant in the nightshade family Solanaceae

Datura stramonium, known by the common names thorn apple, jimsonweed, devil's snare, or devil's trumpet, is a poisonous flowering plant of the nightshade family Solanaceae. It is a species belonging to the Datura genus and Daturae tribe. Its likely origin was in Central America, and it has been introduced in many world regions. It is an aggressive invasive weed in temperate climates and tropical climates across the world. D. stramonium has frequently been employed in traditional medicine to treat a variety of ailments. It has also been used as a hallucinogen, taken entheogenically to cause intense, sacred or occult visions. It is unlikely ever to become a major drug of abuse owing to effects upon both mind and body frequently perceived as being highly unpleasant, giving rise to a state of profound and long-lasting disorientation or delirium with a potentially fatal outcome. It contains tropane alkaloids which are responsible for the psychoactive effects, and may be severely toxic.

<i>Atropa belladonna</i> Species of toxic flowering plant in the nightshade family.

Atropa belladonna, commonly known as belladonna or deadly nightshade, is a toxic perennial herbaceous plant in the nightshade family Solanaceae, which also includes tomatoes, potatoes and aubergine (eggplant). It is native to Europe and Western Asia, including Turkey. Its distribution extends from Ireland in the west to western Ukraine and the Iranian province of Gilan in the east. It is also naturalised or introduced in some parts of Canada, North Africa and the United States.

<span class="mw-page-title-main">Hyoscyamine</span> Tropane alkaloid

Hyoscyamine is a naturally occurring tropane alkaloid and plant toxin. It is a secondary metabolite found in certain plants of the family Solanaceae, including henbane, mandrake, angel's trumpets, jimsonweed, the sorcerers' tree, and Atropa belladonna. It is the levorotary isomer of atropine and thus sometimes known as levo-atropine.

<span class="mw-page-title-main">Besom</span> Type of broom

A besom is a broom, a household implement used for sweeping. The term is mostly reserved for a traditional broom constructed from a bundle of twigs tied to a stout pole. The twigs used could be broom, heather or similar. The song "Buy Broom Buzzems" from Northern England refers to both types of twig. From the phrase broom besom the more common broom comes. In Scotland, besoms are still occasionally to be found at the edge of forests where they are stacked for use in early response to an outbreak of fire.

<i>Hyoscyamus niger</i> Species of plant

Henbane is a poisonous plant in the nightshade family Solanaceae. Henbane is native to temperate Europe and Siberia, and naturalised in Great Britain and Ireland.

<span class="mw-page-title-main">Deliriant</span> Class of psychoactive drugs

Deliriants are a subclass of hallucinogen. The term was coined in the early 1980s to distinguish these drugs from psychedelics such as LSD and dissociatives such as ketamine, due to their primary effect of causing delirium, as opposed to the more lucid and less disturbed states produced by other types of hallucinogens. The term generally refers to anticholinergic drugs, which are substances that inhibit the function of the neurotransmitter acetylcholine. Common examples of deliriants include plants of the genera Datura and Brugmansia as well as higher than recommended dosages of diphenhydramine (Benadryl). A number of plant deliriants such as that of the Solanaceae family, particularly in the Americas have been used by some indigenous cultures to reach delirious and altered states for traditions or rituals, such as rites of passage, divination or communicating with the ancestors. Despite their long history of use, deliriants are the least-studied class of hallucinogens in terms of their behavioral and neurological effects.

<i>Datura innoxia</i> Species of plant

Datura innoxia, known as pricklyburr, recurved thorn-apple, downy thorn-apple, Indian-apple, lovache, moonflower, nacazcul, toloatzin, toloaxihuitl, tolguache or toloache, is a species of flowering plant in the family Solanaceae. It is more rarely called sacred datura, a common name which is applied more often to the closely related Datura wrightii. It is native to the Southwestern United States, Central and South America, and introduced in Africa, Asia, Australia and Europe. The scientific name is often cited as D. innoxia. When English botanist Philip Miller first described the species in 1768, he misspelled the Latin word innoxia (inoffensive) when naming it D. inoxia. The name Datura meteloides was for some time erroneously applied to some members of the species, but that name has now been abandoned.

<span class="mw-page-title-main">Tropane alkaloid</span> Class of chemical compounds

Tropane alkaloids are a class of bicyclic [3.2.1] alkaloids and secondary metabolites that contain a tropane ring in their chemical structure. Tropane alkaloids occur naturally in many members of the plant family Solanaceae. Certain tropane alkaloids such as cocaine and scopolamine are notorious for their psychoactive effects, related usage and cultural associations. Particular tropane alkaloids such as these have pharmacological properties and can act as anticholinergics or stimulants.

Psychochemical warfare — or "drug weapons" — involves the use of psychopharmacological agents with the intention of incapacitating an adversary through the temporary induction of hallucinations or delirium. These agents have generally been considered chemical weapons and, more narrowly, constitute a specific type of incapacitating agent. Although never developed into an effective weapons system, psychochemical warfare theory and research—along with overlapping mind control drug research—was secretly pursued in the mid-20th century by the US military and Central Intelligence Agency (CIA) in the context of the Cold War. These research programs were ended when they came to light and generated controversy in the 1970s. The degree to which the Soviet Union developed or deployed similar agents during the same period remains largely unknown.

<i>Scopolia carniolica</i> Species of plant

Scopolia carniolica, the European scopolia or henbane bell, is a poisonous plant belonging to the family Solanaceae. It has dark violet flowers on long hanging stems. It grows to 60 centimetres (24 in) in height. Its toxicity derives from its high levels of tropane alkaloids, particularly atropine. The concentration of atropine is highest in the roots.

<span class="mw-page-title-main">Hyoscyameae</span> Tribe of flowering plants

Hyoscyameae is an Old World tribe of the subfamily Solanoideae of the flowering plant family Solanaceae. It comprises eight genera: Anisodus, Archihyoscyamus, Atropa, Atropanthe, Hyoscyamus, Physochlaina, Przewalskia and Scopolia. The genera Archihyoscyamus, Atropanthe and Przewalskia are monotypic, the first being endemic to Turkey and Iran, the second to China and the third to Tibet.

<span class="mw-page-title-main">Solanaceae</span> Family of flowering plants that includes tomatoes, potatoes and tobacco

The Solanaceae, or the nightshades, are a family of flowering plants that ranges from annual and perennial herbs to vines, lianas, epiphytes, shrubs, and trees, and includes a number of agricultural crops, medicinal plants, spices, weeds, and ornamentals. Many members of the family contain potent alkaloids, and some are highly toxic, but many—including tomatoes, potatoes, eggplant, bell and chili peppers—are used as food. The family belongs to the order Solanales, in the asterid group and class Magnoliopsida (dicotyledons). The Solanaceae consists of about 98 genera and some 2,700 species, with a great diversity of habitats, morphology and ecology.

<i>Atropa baetica</i> Species of flowering plant

Atropa baetica, commonly known as the Andalusian belladonna, is one of Europe's rarest wildflowers. A close relative of the infamous deadly nightshade, its specific name derives from that of the Roman province of Hispania Baetica, while its common name refers to the Spanish region of Andalucía – both designating the area in the south of Spain where it is most frequently encountered. It is an attractive perennial plant with a herbaceous habit, bearing infundibuliform, yellow or greenish flowers and shiny, black berries. Like the other three species of Atropa, it is an extremely poisonous plant, containing a variety of tropane alkaloids with anticholinergic, deliriant, antispasmodic and mydriatic properties. Although most populations of the plant are to be found in Spain, it is not wholly confined to the Iberian Peninsula of Europe, occurring also in certain localities in Morocco and Algeria in the Atlas Mountains of North Africa. The Rif and the Baetic System, which face each other across the Alboran Sea, together constitute one of the finest of the Mediterranean biodiversity hotspots – rich in endemic species, of which Atropa baetica is a notable example..

<span class="mw-page-title-main">Ernest Ayscoghe Floyer</span> English colonial official and explorer

Ernest Ayscoghe Floyer (1852–1903) was a British colonial official, and explorer in Baluchistan and the Sudan. He explored the economically useful plants and materials of interest along his travels. He was put in charge of extracting nitrate of soda after discovering a deposit of it in Egypt and later served as inspector general of telegraphs in Egypt.

<i>Physochlaina</i> Genus of flowering plants in the nightshade family Solanaceae

Physochlaina is a small genus of herbaceous perennial flowering plants belonging to the nightshade family, Solanaceae, found principally in the north-western provinces of China although one species occurs in Western Asia, while another is found as far east as those regions of Siberia abutting the eastern borders of Mongolia and, furthermore, not only in Mongolia itself, but also in the Chinese autonomous region of Inner Mongolia. Some sources maintain that the widespread species P. physaloides is found also in Japan, but the species is not recorded as being native in one of the few English-language floras of the country. The genus is a valuable one, since its species are not only of considerable medicinal value, being rich in tropane alkaloids, but also of ornamental value, three species having been grown for the purpose, although hitherto infrequently outside botanical gardens. Furthermore, the genus contains a species formerly used as an entheogen in Siberia.

<span class="mw-page-title-main">Paul Flatters</span> French soldier (1832-1881)

Paul Flatters was a French soldier who spent a long period as a military administrator in Algeria. He is known as leader of the Flatters expedition, an ill-fated attempt to explore the route of a proposed Trans-Saharan railway from Algeria to the Sudan. Almost all members of the expedition were massacred by hostile Tuaregs. The survivors resorted to eating grass and to cannibalism on the long retreat through the desert. After a brief outburst of public indignation the fiasco was forgotten.

<span class="mw-page-title-main">Bir el-Garama</span> Well in Tamanrasset, Algeria

Bir el-Garama is a well in the south of Algeria in Tamanrasset Province, 150 kilometres (93 mi) northeast of Tamanrasset, known as the site where a large part of the French colonial Flatters Expedition was wiped out by Tuaregs. It is better known on French maps by its Tamahaq language name: Tagmout T-an Koufar, or 'well of the foreigner'.

References

  1. 1 2 3 4 Fern 2014.
  2. Cornish 1912.
  3. Hyoscyamus muticus – EOL.
  4. 1 2 Wilkinson 2011.
  5. Brower 2011, p. 240.
  6. Ney 1891, p. 636.
  7. Ney 1891, p. 637.

Sources