S-Adenosyl methionine (SAM), also known under the commercial names of SAMe, SAM-e, or AdoMet, is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver. More than 40 methyl transfers from SAM are known, to various substrates such as nucleic acids, proteins, lipids and secondary metabolites. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase. SAM was first discovered by Giulio Cantoni in 1952.
In enzymology, a 3,7-dimethylquercetin 4'-O-methyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a 3-demethylubiquinone-9 3-O-methyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a 3-methylquercetin 7-O-methyltransferase is an enzyme that catalyzes the chemical reaction
Amine N-methyltransferase, also called indolethylamine N-methyltransferase, and thioether S-methyltransferase, is an enzyme that is ubiquitously present in non-neural tissues and catalyzes the N-methylation of tryptamine and structurally related compounds. More recently, it was discovered that this enzyme can also catalyze the methylation of thioether and selenoether compounds, although the physiological significance of this biotransformation is not yet known.
In enzymology, a caffeate O-methyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a cyclopropane-fatty-acyl-phospholipid synthase is an enzyme that catalyzes the chemical reaction
In enzymology, a hexaprenyldihydroxybenzoate methyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a methionine S-methyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a mRNA (2'-O-methyladenosine-N6-)-methyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, an adenosylmethionine hydrolase (EC 3.3.1.2) is an enzyme that catalyzes the chemical reaction
In enzymology, an adenosylhomocysteine nucleosidase (EC 3.2.2.9) is an enzyme that catalyzes the chemical reaction
In enzymology, lovastatin nonaketide synthase (EC 2.3.1.161) is an enzyme that catalyzes the chemical reaction
In enzymology, an adenosylmethionine cyclotransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a discadenine synthase (EC 2.5.1.24) is an enzyme that catalyzes the chemical reaction
In enzymology, a nicotianamine synthase is an enzyme that catalyzes the chemical reaction
In enzymology, a tRNA-uridine aminocarboxypropyltransferase is an enzyme that catalyzes the chemical reaction
16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase (EC 2.1.1.182, S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase, KsgA, ksgA methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase. This enzyme catalyses the following chemical reaction
Acyl-homoserine-lactone synthase is an enzyme with systematic name acyl-(acyl-carrier protein):S-adenosyl-L-methionine acyltranserase . This enzyme catalyses the following chemical reaction
5′-Methylthioadenosine is S-methyl derivative of the adenosine. It is an intermediate in the methylthioadenosine (MTA) cycle, also known as the methionine salvage pathway that is universal to aerobic life.
