John Jacob Abel was an American biochemist and pharmacologist. He established the pharmacology department at Johns Hopkins University School of Medicine in 1893, and then became America's first full-time professor of pharmacology. During his time at Hopkins, he made several important medical advancements, especially in the field of hormone extraction. In addition to his laboratory work, he founded several significant scientific journals such as the Journal of Biological Chemistry and the Journal of Pharmacology and Experimental Therapeutics.
Virgil Craig Jordan,, is a scientist with American and British citizenship specializing in drugs for breast cancer treatment and prevention. Currently, he is Professor of Breast Medical Oncology, and Professor of Molecular and Cellular Oncology at the University of Texas MD Anderson Cancer Center, Houston, Texas. Previously, he was Scientific Director and Vice Chairman of Oncology at the Lombardi Comprehensive Cancer Center of Georgetown University. Jordan was the first to discover the breast cancer prevention properties of tamoxifen and the scientific principles for adjuvant therapy with antihormones. More recently his work has branched out into the prevention of multiple diseases in women with the discovery of the drug group, selective estrogen receptor modulator (SERMs). Currently, he plans to develop a new Hormone Replacement Therapy (HRT) for post-menopausal women that prevents breast cancer and does not increase the risk of breast cancer.
G protein-coupled receptor 35 also known as GPR35 is a G protein-coupled receptor which in humans is encoded by the GPR35 gene. Heightened expression of GPR35 is found in immune and gastrointestinal tissues, including the crypts of Lieberkühn.
Andarine is an investigational selective androgen receptor modulator (SARM) developed by GTX, Inc for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy (BPH), using the nonsteroidal antiandrogen bicalutamide as a lead compound.
SB-612,111 is an opioid receptor ligand which is a potent and selective antagonist for the nociceptin receptor (ORL-1), several times more potent than the older drug J-113,397. It does not have analgesic effects in its own right, but prevents the development of hyperalgesia, and also shows antidepressant effects in animal studies.
The American Society for Pharmacology and Experimental Therapeutics (ASPET) is a scientific society founded in late 1908 by John Jacob Abel of Johns Hopkins University, with the aim of promoting the growth of pharmacological research. Many society members are researchers in basic and clinical pharmacology who help develop disease-fighting medications and therapeutics. ASPET is one of the constituent societies of the Federation of American Societies for Experimental Biology (FASEB). The society's headquarters are in Rockville, MD. The current president is Michael F. Jarvis.
Molecular Pharmacology is a peer-reviewed scientific journal published by the American Society for Pharmacology and Experimental Therapeutics since 1965. It is indexed in MEDLINE, Meta, Scopus, and other databases.
4-Methylamphetamine is a stimulant and anorectic drug of the phenethylamine and amphetamine chemical classes.
Pharmacological Reviews is a quarterly peer-reviewed scientific journal publishing review articles on all aspects of pharmacology and related topics. It is published by the American Society for Pharmacology and Experimental Therapeutics. The editor-in-chief is Eric Barker.
Clinical and Translational Science is a bimonthly peer-reviewed open-access medical journal covering translational medicine. It is published by Wiley-Blackwell and is an official journal of the American Society for Clinical Pharmacology and Therapeutics. The journal was established in 2008 and the editor-in-chief is John A. Wagner.
Drug Metabolism and Disposition is a peer-reviewed scientific journal covering the fields of pharmacology and toxicology. It was established in 1973 and is published monthly by the American Society for Pharmacology and Experimental Therapeutics. The journal publishes articles on in vitro and in vivo studies of the metabolism, transport, and disposition of drugs and environmental chemicals, including the expression of drug-metabolizing enzymes and their regulation. As of 2022, the editor-in-chief is XinXin Ding.
Hopeaphenol is a stilbenoid. It is a resveratrol tetramer. It has been first isolated from Dipterocarpaceae like Shorea ovalis. It has also been isolated from wines from North Africa.
The John J. Abel Award is an annual award presented by the American Society for Pharmacology and Experimental Therapeutics (ASPET). The award is given for outstanding research in the field of pharmacology and/or experimental therapeutics; which comes with a $5000 prize, An engraved plaque, and all travel expenses paid to attend the ASPET Annual Meeting at Experimental Biology. The Award is named after American biochemist and pharmacologist, John Jacob Abel.
Dihexa, also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. The compound has been found to potently improve cognitive function in animal models of Alzheimer's disease-like mental impairment. In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor.
Dixon Miles Woodbury (1921–1991) was an American epilepsy researcher and distinguished professor of Physiology and Pharmacology at the University of Utah School of Medicine. His research helped clarify the causes of seizure disorders and the mechanisms of anticonvulsant drugs. He published over 300 scientific articles and edited several books on epilepsy, including the first two volumes of Antiepileptic Drugs. His awards include the John Jacob Abel Award from the American Society for Pharmacology and Experimental Therapeutics (ASPET); the Epilepsy Research Award from the International League Against Epilepsy; Research Career Award from the National Institutes of Health; and William G. Lennox Award for outstanding research in epilepsy from the American Epilepsy Society.
Namandjé N. Bumpus is an American pharmacologist and the Chief Scientist of the Food and Drug Administration. She was previously director of the department of pharmacology and molecular sciences at Johns Hopkins University School of Medicine, where she holds the E.K. Marshall and Thomas H. Maren professorship in pharmacology. Bumpus is known for her research on the metabolism of antiviral drugs used to treat HIV-1 and how genetic variations in drug-processing enzymes may impact these drugs' efficacy. Bumpus received a Presidential Early Career Award for Scientists and Engineers in 2016.
Lee Limbird is a pharmacologist, Dean of the School of Natural Science, Mathematics and Business & Professor in the Department of Life and Physical Sciences at Fisk University, Nashville, Tennessee.
Eva King Killam was a research pharmacologist who studied the activity of drugs on the brain and behavior, developing animal models for epilepsy and opiate dependence.
John Stephen Lazo is an American pharmacologist noted for his work discovering the fundamental mechanisms of action of small molecule therapeutics and the factors that confer drug resistance. He is a professor emeritus of pharmacology at University of Virginia.
