L-aminoadipate-semialdehyde dehydrogenase

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L-aminoadipate-semialdehyde dehydrogenase
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Alpha-aminoadipic semialdehyde dehydrogenase tetramer, Human
Identifiers
EC no. 1.2.1.31
CAS no. 9067-87-2
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In enzymology, a L-aminoadipate-semialdehyde dehydrogenase (EC 1.2.1.31) is an enzyme that catalyzes the chemical reaction

L-2-aminoadipate 6-semialdehyde + NAD(P)+ + H2O L-2-aminoadipate + NAD(P)H + H+

The 4 substrates of this enzyme are L-2-aminoadipate 6-semialdehyde, NAD+, NADP+, and H2O, whereas its 4 products are L-2-aminoadipate, NADH, NADPH, and H+.

This enzyme participates in lysine biosynthesis and biodegradation.

Nomenclature

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-2-aminoadipate-6-semialdehyde:NAD(P)+ 6-oxidoreductase. Other names in common use include:

Related Research Articles

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References