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This is a list of singles that charted in the top ten of the Billboard Hot 100 during 2001.
Ja Rule and Destiny's Child each had four top-ten hits in 2001, tying them for the most top-ten hits during the year.
| Top ten entry date | Single | Artist(s) | Peak | Peak date | Weeks in top ten |
|---|---|---|---|---|---|
| Singles from 2000 | |||||
| November 18 | "The Way You Love Me" | Faith Hill | 6 | January 13 | 13 |
| December 2 | "It Wasn't Me" | Shaggy featuring Rikrok | 1 | February 3 | 16 |
| December 16 | "Ms. Jackson" | Outkast | 1 | February 17 | 12 |
| December 30 | "If You're Gone" (#6) | Matchbox Twenty | 5 | January 27 | 10 |
| "Dance with Me" | Debelah Morgan | 8 | January 6 | 3 | |
| Singles from 2001 | |||||
| January 6 | "Liquid Dreams" | O-Town | 10 | January 6 | 1 |
| January 20 | "Again" (#9) | Lenny Kravitz | 4 | February 17 | 14 |
| "Love Don't Cost a Thing" | Jennifer Lopez | 3 | February 24 | 10 | |
| February 3 | "Don't Tell Me" | Madonna | 4 | February 3 | 8 |
| "Stutter" | Joe featuring Mystikal | 1 | February 24 | 14 | |
| February 17 | "Angel" | Shaggy featuring Rayvon | 1 | March 31 | 14 |
| February 24 | "Put It on Me" | Ja Rule featuring Lil' Mo and Vita | 8 | March 24 | 7 |
| March 10 | "Butterfly" | Crazy Town | 1 | March 24 | 8 |
| "It's Over Now" | 112 | 6 | March 17 | 3 | |
| "Promise" | Jagged Edge | 9 | March 10 | 3 | |
| March 24 | "All for You" (#3) | Janet Jackson | 1 | April 14 | 14 |
| March 31 | "Thank You" (#8) | Dido | 3 | April 28 | 11 |
| "Survivor" | Destiny's Child | 2 | April 14 | 11 | |
| "Get Over Yourself" ↑ | Eden's Crush | 8 | March 31 | 3 | |
| "Jaded" | Aerosmith | 7 | April 7 | 3 | |
| April 14 | "Missing You" | Case | 4 | April 28 | 5 |
| "Stranger in My House" | Tamia | 10 | April 14 | 2 | |
| April 21 | "Hanging by a Moment" (#1) | Lifehouse | 2 | June 16 | 20 |
| April 28 | "Ride wit Me" | Nelly featuring City Spud | 3 | June 23 | 12 |
| May 5 | "Follow Me" | Uncle Kracker | 5 | June 9 | 8 |
| "Lady Marmalade" | Christina Aguilera, Lil' Kim, Mýa and Pink | 1 | June 2 | 12 | |
| May 12 | "Never Had a Dream Come True" | S Club 7 | 10 | May 12 | 2 |
| May 19 | "What Would You Do?" | City High | 8 | May 26 | 4 |
| May 26 | "I'm Like a Bird" | Nelly Furtado | 9 | May 26 | 1 |
| "Get Ur Freak On" | Missy Elliott | 7 | June 30 | 7 | |
| June 2 | "Fiesta" | R. Kelly featuring Jay-Z | 6 | June 23 | 6 |
| June 9 | "My Baby" | Lil' Romeo | 3 | June 30 | 5 |
| June 16 | "Drops of Jupiter (Tell Me)" (#4) | Train | 5 | June 23 | 14 |
| "Peaches & Cream" | 112 | 4 | July 7 | 8 | |
| June 30 | "Let Me Blow Ya Mind" (#7) | Eve featuring Gwen Stefani | 2 | August 18 | 17 |
| "There You'll Be" | Faith Hill | 10 | June 30 | 1 | |
| July 7 | "U Remind Me" | Usher | 1 | July 7 | 16 |
| July 14 | "Hit 'Em Up Style (Oops!)" | Blu Cantrell | 2 | July 21 | 16 |
| "Bootylicious" | Destiny's Child | 1 | August 4 | 6 | |
| "Drive" | Incubus | 9 | July 28 | 3 | |
| July 21 | "All or Nothing" | O-Town | 3 | July 28 | 6 |
| August 4 | "Loverboy" | Mariah Carey featuring Cameo | 2 | August 4 | 3 |
| "Fallin'" (#2) | Alicia Keys | 1 | August 18 | 19 | |
| August 11 | "I'm Real" (#5) | Jennifer Lopez featuring Ja Rule | 1 | September 8 | 19 |
| "Where the Party At" | Jagged Edge featuring Nelly | 3 | September 15 | 13 | |
| August 25 | "It's Been Awhile" | Staind | 5 | October 20 | 12 |
| September 1 | "Someone to Call My Lover" | Janet Jackson | 3 | September 1 | 6 |
| September 22 | "Family Affair" | Mary J. Blige | 1 | November 3 | 19 |
| "You Rock My World" | Michael Jackson | 10 | September 22 | 1 | |
| September 29 | "Izzo (H.O.V.A.)" | Jay-Z | 8 | October 20 | 5 |
| October 13 | "Differences" | Ginuwine | 4 | October 27 | 15 |
| October 27 | "The Star Spangled Banner" | Whitney Houston | 6 | October 27 | 1 |
| "Hero" | Enrique Iglesias | 3 | November 17 | 14 | |
| November 3 | "Turn Off the Light" | Nelly Furtado | 5 | November 10 | 8 |
| "U Got It Bad" | Usher | 1 | December 15 | 20 | |
| "Livin' It Up" | Ja Rule featuring Case | 6 | December 8 | 9 | |
| November 10 | "Only Time" | Enya | 10 | November 10 | 3 |
| November 17 | "How You Remind Me" | Nickelback | 1 | December 22 | 23 |
| December 1 | "Emotion" | Destiny's Child | 10 | December 1 | 1 |
| December 8 | "Get the Party Started" | Pink | 4 | December 29 | 12 |
| December 15 | "Whenever, Wherever" | Shakira | 6 | December 29 | 8 |
| Top ten entry date | Single | Artist(s) | Peak | Peak date | Weeks in top ten |
|---|---|---|---|---|---|
| September 30 | "With Arms Wide Open" | Creed | 1 | November 11 | 18 |
| November 4 | "This I Promise You" | 'N Sync | 5 | December 2 | 9 |
| "Independent Women Part I" (#10) | Destiny's Child | 1 | November 18 | 17 | |
| "Case of the Ex" | Mýa | 2 | December 2 | 13 | |
| December 16 | "He Loves U Not" | Dream | 2 | December 30 | 11 |
| Top ten entry date | Single | Artist(s) | Peak | Peak date | Weeks in top ten |
|---|---|---|---|---|---|
| December 22 | "Always on Time" | Ja Rule featuring Ashanti | 1 | February 23 | 16 |
| December 29 | "My Sacrifice" | Creed | 4 | February 9 | 11 |
| Artist | Numbers of songs |
|---|---|
| Destiny's Child | 4 |
| Ja Rule | |
| Shaggy | 2 |
| Faith Evans | |
| 112 | |
| O-Town | |
| Jennifer Lopez | |
| Jagged Edge | |
| Nelly | |
| Janet Jackson | |
| Jay-Z | |
| Nelly Furtado | |
| Usher | |
| Case | |
| Pink | |
| Creed | |
This is a list of songs that have peaked at number one on the Billboard Hot 100 and the magazine's national singles charts that preceded it. Introduced in 1958, the Hot 100 is the pre-eminent singles chart in the United States, currently monitoring the most popular singles in terms of popular radio play, single purchases and online streaming.