General Hospital is a long-running American television serial drama, airing on ABC. [1] Created by Frank and Doris Hursley, the series premiered on April 1, 1963. Former cast member Rachel Ames was previously the series' longest-running cast member, portraying Audrey Hardy from 1964 to 2007, and making guest appearances in 2009 and 2013, the latter for the series' fiftieth anniversary. [2] Ames made a special appearance on October 30, 2015. [3] [4] Anthony Geary, who has portrayed Luke Spencer, was the fourth longest-running cast member, having joined General Hospital in November 1978. [5] Geary made his last appearance on May 4, 2017. [6] This is a list of previous cast members.
| Actor | Character | Duration |
|---|---|---|
| Julie Adams | Denise Wilton | 1969 |
| Marla Adams | Mildred Deal | 1963 |
| R. J. Adams | Frank | 1980–1983 |
| Robert Adamson | Michael Corinthos | 2022, 2024 |
| Lexi Ainsworth | Kristina Davis | 2009–2011, 2015–2023 |
| Crispin Alapag | Heavy | 2014–15 |
| Christian Alexander | Kiefer Bauer | 2009–10 |
| Denise Alexander | Lesley Webber | 1973–84, 1996–2009, 2013, 2017, 2019, 2021 |
| Kristen Alderson | Starr Manning | 2012–13 |
| Kiki Jerome | 2013–15 | |
| Aki Aleong | Mr. Wu | 1985 |
| Jed Allan | Edward Quartermaine | 2004–05 |
| Christopher Allen | CPO Hicks | 2013 |
| Tessa Allen | Molly Farrell | 2004 |
| Lulu Spencer | 2004–2005 | |
| Cristela Alonzo | Natalia Rodriguez | 2015 |
| George Alvarez | Alex Garcia | 1992-99 |
| Rachel Ames | Audrey Hardy | 1964–2007, 2009, 2013, 2015 |
| Richard Dean Anderson | Jeff Webber | 1976–81 |
| Lori and Sevan Andonian | Scout Cain | 2017 |
| Starr Andreeff | Jessica Holmes | 1991–93 |
| Réal Andrews | Marcus Taggert | 1996–2003, 2020–23 |
| Gerald Anthony | Marco Dane | 1992–93 |
| Vinessa Antoine | Jordan Ashford | 2014–18 |
| Ashton Arbab | Dev Cerci | 2019–20 |
| Michelle Argyris | Kendra Lennon | 2019 |
| India Arie | Herself | 2015 [7] |
| Dimitra Arliss | Helena Cassadine | 1996 |
| Tom Arnold | Billy Boggs | 1994 |
| Senait Ashenafi | Keesha Ward | 1994–98 |
| Matthew Ashford | Tom Hardy | 1995–97 |
| Barry Atwater | John Prentice | 1964–67 |
| Jerry Ayres | David Hamilton | 1977–78 |
| Donna Baccala | Gina Dante-Lansing | 1978–79 |
| Philip Baker Hall | Judge Simpson | 1983 |
| Scott Thompson Baker | Colton Shore | 1988–91 |
| Stacey Baldwin | Laura Spencer | 1974–76 |
| Brandon Barash | Johnny Zacchara | 2007–16 |
| Harper Rose Barash | Georgie Spinelli | 2015 |
| Adrienne Barbeau | Suzanne Stanwyck | 2010–11 |
| Roseanne Barr | Jennifer Smith | 1994 |
| Majel Barrett | Bea | 1983 |
| William H. Bassett | Norton Carter | 1983 |
| Wolfgang Von Schuler | 1987 | |
| Jennifer Bassey | Quinn Danvers | 2017 |
| Susan Batten | Flora Gardens | 2022–23 |
| Nicolas Bechtel | Spencer Cassadine | 2013–20 |
| Kabir Bedi | Rama | 1983 |
| Gregory Beecroft | Jonathan Paget | 1990 |
| Brandon Beemer | Seth | 2005–06 |
| Chris Beetem | Nikolas Cassadine | 2005 |
| Sam Behrens | Jake Meyer | 1983–88 |
| Robert Beitzel | Steven Webber | 1977 |
| Shari Belafonte | Janice Lomax | 2016–17 |
| Felecia Bell | Simone Ravelle Hardy | 1993–96 |
| Joshua Benard | Sonny Corinthos | 2018 |
| Adam Wright | 2022–23 | |
| Fran Bennett | Flora Johnston | 1983 |
| Meg Bennett | Allegra Montenegro | 2005 |
| Shaun Benson | Steven Webber | 2004–05 |
| Daniel Benzali | Theo Hoffman | 2010–11 |
| John Beradino | Steve Hardy | 1963–96 |
| Milton Berle | Mickey Miller | 1981–82 |
| Julie Marie Berman | Lulu Spencer | 2005–13 |
| Robyn Bernard | Terry Brock | 1984–90 |
| Kevin Bernhardt | Frisco Jones | 1984 |
| Kevin O'Connor | 1985–86 | |
| Corbin Bernsen | John Durant | 2004–06 |
| Blake Berris | Damian Spinelli | 2017 |
| Jack Betts | Ken Martin | 1963 |
| AnaSofia Bianchi [8] | Charlotte Cassadine | 2023 |
| Casey Biggs [9] [10] | Chad Wainwright | 1990 |
| Dr Lasaris | 2018 | |
| Patricia Bethune | Nurse Mary Pat | 2018 |
| Loanne Bishop | Rose Kelly | 1980–84 |
| Martin Blaine | Dr. Lyons | 1965 |
| Andrea Bogart | Abby Haver | 2010–11 |
| John Bolger | Prescott Floyd | 2006–12 |
| Steve Bond | Jimmy Lee Holt | 1983–87 |
| Nazanin Boniadi | Leyla Mir | 2007–09 |
| Jay Bontatibus | Andy Capelli | 2002–04 |
| Angel Boris | Angel Sorel Ellis | 2001 |
| Wil Bowers | Ward Administrator | 2002 |
| Doctor | 2005 | |
| Maitre'd | 2013 | |
| Ferncliff Aide | 2014 | |
| Eileen April Boylan | Sage Alcazar | 2003 |
| Chad Brannon | Zander Smith | 2000–04, 2021 |
| Aaron | 2009 | |
| Jennifer Bransford | Carly Corinthos | 2005 |
| Tamara Braun | Carly Corinthos | 2001–05, 2014 |
| Kim Nero | 2017–19 | |
| Patricia Breslin | Meg Baldwin | 1965–69 |
| Marc Brett | Zander Smith | 2000 |
| Brianna Brown | Lisa Niles | 2010–11 |
| Kimberly J. Brown | Chloe Jennings | 2021 |
| Kimberlin Brown | Rachel Locke | 1999–2002 |
| Sarah Joy Brown | Carly Corinthos | 1996–2001, 2014 |
| Claudia Zacchara | 2008–09 | |
| Susan Brown | Gail Adamson Baldwin | 1977–85, 1989–90, 1992–2002, 2004 |
| Tom Brown | Al Weeks | 1963–65, 1970–74 |
| Argentina Brunetti | Filomena Soltini | 1985–88 |
| Breck Bruns | Georgie Jones | 1997–2002 |
| Ian Buchanan | Duke Lavery | 1986–89, 2012–17, 2020 |
| Cesar Faison | 2012 | |
| Jensen Buchanan | Melissa Bedford | 2001–02 |
| Rebecca Budig | Hayden Barnes | 2015–17, 2019 |
| Paulina Bugembe | Valerie Spencer | 2019–20 |
| Brooke Bundy | Diana Taylor | 1977–81 |
| Dan Buran [11] | Linc Brown | 2020, 2022–23 |
| Richard Burgi | Paul Hornsby | 2015–16 |
| Molly Burnett | Maxie Jones [12] [13] [14] | 2016, 2018 |
| Bonnie Burroughs | Gladys Corbin | 2019–23 |
| Lindsay Bushman | Kate Howard | 2011 |
| Nathin Butler | Ewen Keenan | 2011–12 |
| Caitlyn Buton | Hope Manning-Thornhart | 2012 |
| Martha Byrne | Andrea Floyd | 2009 |
| Kurt Caceres | Javier | 2011 |
| Inga Cadranel | Harmony Miller | 2019–23 |
| Erin Cahill | Cassandra | 2007 |
| John Cahill | Bartender | 2016–19 |
| Tony Camp | Scott Baldwin | 1969–72 |
| John Callahan [15] | Leo Russell | 1984–85 |
| Mary Grace Canfield | Lucille March Weeks | 1978 |
| John Capodice | Carmine Cerullo | 1994-95 |
| Gloria Carlin | Charity Gatlin | 1986 |
| Steve Carlson | Gary Lansing | 1977–79 |
| Ryan Carnes | Lucas Jones | 2004–05, 2014–20 |
| Phil Brewer | 2015 | |
| Veronica Cartwright | Sibley Gamble | 2019 |
| Paul Carr | Peter Taylor | 1967 |
| Milton Stanus | 1994 | |
| Tia Carrere | Jade Soong Chung | 1985–87 |
| Laura Carrington | Simone Ravelle Hardy | 1987–89 |
| Crystal Carson | Julia Barrett | 1991–93, 1997–98 |
| Sharon Case | Dawn Winthrop | 1989–90 |
| Dylan Cash | Michael Corinthos | 2002–08 |
| Rosalind Cash | Mary Mae Ward | 1994–95 |
| Shaun Cassidy | Dusty Walker | 1987–88 |
| Gerald Castillo | Judge Davis Wagner | 1992-94 |
| Teresa Castillo | Sabrina Santiago | 2012–16 |
| Amy Castle | Tara | 2009 |
| Jonathan Carter | Jason Vining | 1975–76 |
| Lisa Cerasoli | Venus Ardanowski | 1997–99 |
| Erin Chambers | Siobhan McKenna | 2010–11 |
| Brett Chapin | Roger Barstow | 2021 |
| District Attorney | 2021 | |
| Judith Chapman | Ginny Blake | 1984–86 |
| Leslie Charleson | Monica Quartermaine | 1977–2023 |
| Mary Butler | 2020 | |
| Don Chastain | Tom Baldwin | 1967–77 |
| Nicholas Chavez | Spencer Cassadine | 2021–24 |
| Maree Cheatham | Charlene Simpson | 1987–91, 1997 |
| Nick Chinlund | Mickey Diamond | 2014 |
| Paul Chirico | Jason Morgan | 2017 |
| Maksim Chmerkovskiy | Anton Ivanov | 2013 |
| Valentin Chmerkovskiy | Boxer | 2012 |
| Robin Christopher | Abby Mitchell | 1993 |
| Skye Chandler | 2001–08, 2010–12 | |
| Tyler Christopher | Nikolas Cassadine | 1996–99, 2003–11, 2013–16 |
| Connor Bishop | 2004–05 | |
| Christie Clark | Cindy | 1992 |
| Brian Patrick Clarke | Grant Andrews | 1983–85 |
| Grant Putnam | 1983, 1985–88 | |
| Don Clarke | Scott Baldwin | 1973–74 |
| Robert Clarke | Roy Lansing | 1963 |
| Robert Clary | French Man | 1985 |
| Tamara Clatterbuck | Tammy Hansen | 2000–01 |
| Scott Clifton | Dillon Quartermaine | 2003–07 |
| Gina Coconato | Alicia | 2015–16 |
| Claire Coffee | Nadine Crowell | 2007–09 |
| Matt Cohen | Griffin Munro | 2016–19 |
| Bradley Cole | Warren Bauer | 2010 |
| Michael Cole | Harlan Barrett | 1991 |
| Booth Colman | Prof. Hector Jerrold | 1983 |
| John Colicos | Mikkos Cassadine | 1981 |
| Petros Cassadine | 1984–85 | |
| Marcus Coloma | Nikolas Cassadine | 2019–23 |
| Jason Connery | Sebastian Leeds | 2013 |
| Norma Connolly | Ruby Anderson | 1979–98 |
| Jason Cook | Matt Hunter | 2008–12 |
| Cami Cooper | Nikki Langton | 1992–93 |
| Aneta Corsaut | Jessie Brewer | 1976 |
| Joseph Cortese | Frank Smith | 2015 |
| Ward Costello | Martin Drake | 1983–89 |
| Katie Couric | Kelly Curtis | 2013 |
| Christopher Cousins | Warren Kirk | 2020 |
| Nikki Cox | Gina Cates | 1993–95 |
| Patrick Cox [10] | Rupert Watson | 2018 |
| Josh Coxx | Brendan Byrne | 2020, 2022 |
| Bryan Craig | Morgan Corinthos | 2013–16, 2018, 2024 |
| Gianna Marie Crane | Lila Rae Alcazar | 2006–08 |
| Pat Crowley | Mary Scanlon | 1997 |
| Denise Crosby | Carolyn Webber | 2022–23 |
| Jason Culp | Julian Jerome | 1988–90 |
| Daniel Cummings | Taylor Wallace | 2010–11 |
| Augusta Dabney | Caroline Chandler Baldwin | 1975–76 |
| Tyne Daly | Caroline Beale | 1968 |
| Stuart Damon | Alan Quartermaine | 1977–2008, 2011–13 |
| Tiffany Daniels | Jordan Ashford | 2021 |
| Shell Danielson | Dominique Baldwin | 1991–93 |
| Henry Darrow | Ambassador Tabris | 1982 |
| DVX-backed Colonel | 1987 | |
| Jason David | Aiden Spencer | 2012–13, 2015–21 |
| Lane Davies | Cameron Lewis | 2002–04 |
| Kristin Davis | Betsy Chilson | 1991 |
| Sammy Davis, Jr. | Eddie Phillips | 1983 |
| Todd Davis | Bryan Phillips | 1978–87 |
| Bruce Davison | Wilhelm VonSchlagel | 2010 |
| Davey Davison | Diana Taylor | 1977 |
| Trent Dawson | Huxley Lynch | 2016–17 |
| Enzo De Angelis | Aiden Spencer | 2021–24 |
| Celesta DeAstis [16] | Avery Corinthos | 2018 |
| Francesca Cavallo | 2018 | |
| Diane Delano | Margarethe | 2016 |
| Michael Delano | Mark Dante | 1976 |
| Isaiah Dell | Leo Falconeri | 2022 |
| Kassie DePaiva | Blair Cramer | 2012, 2023 |
| James DePaiva | David Bensch | 2017–18 |
| Robb Derringer | Kyle Sloane | 2014–15 |
| Jimmy Deshler | Rafe Kovich | 2013–14 |
| William deVry | Julian Jerome | 2013–20 |
| Stephanie Dicker | Gina Cates | 1996–97 |
| Eileen Dietz | Sarah Abbott | 1981–83 |
| Susan Diol [17] | Alexis Davis | 2001–2002 |
| Clara | 2023 | |
| Jeff Donnell | Stella Fields | 1979–88 |
| Jack Donner | Alfred | 2006–2010 |
| Tony Dow | Ross Jeanelle | 1975 |
| Lieux Dressler | Alice Grant | 1978–1983 |
| Chad Duell | Michael Corinthos | 2010–2025 |
| Josh Duhon | Logan Hayes | 2007–2008 |
| Linda Dona | Nancy Eckert | 1991 |
| Michael Easton | John McBain | 2012–2013 |
| Stephen Clay | 2013 | |
| Silas Clay | 2013–2015 | |
| Hamilton Finn | 2016–2024 | |
| Ted Eccles | Bobby Chandler Baldwin | 1975–1976 |
| Sonya Eddy | Epiphany Johnson | 2006–2022 |
| Hilary Edson | Tania Jones | 1984–1987 |
| Evan Ellingson | Young Luke Spencer | 2001 |
| Ross Elliott | Lee Baldwin | 1963–65 |
| Saidah Arrika Ekulona | Janice Lomax | 2012–13, 2015 |
| Gideon Emery | Jasper Jacks | 2008 |
| Kyler and Caleb Ends [18] | James West | 2019 |
| Wiley Cooper-Jones | 2021 | |
| Stephanie Erb | Alexis Davis | 2022 |
| Ethan Erickson | Patrick Drake | 2008 |
| Kristen Erickson | Alexis Davis | 2006 |
| Hayley Erin | Kiki Jerome | 2015–19 |
| Mary Beth Evans | Katherine Bell | 1993–99 |
| Greg Evigan [19] | Jim Harvey | 2017–18 |
| Morgan Fairchild | Sydney Chase | 1996 |
| Haven de Havilland | 2022–23 | |
| Rick Falk | Phil Brewer | 1966 |
| Richard Fancy | Bennie Abrahms | 1997–03 |
| Bernie Abrahms | 2006–12 | |
| Gene Farber [20] | Richard Klein | 2017 |
| Bianca Ferguson | Claudia Johnston Phillips | 1978–87 |
| Sandra Ferguson | Felicia Jones | 2005 |
| Charlotte Cassadine | 2016–2021, 2023–2025 | |
| Jessica Ferrarone | Lydia Karenin | 2003 |
| Mitchell Fink | William Eichner | 2014 |
| Gail Fisher | Judge Heller | 1982 |
| Chrissie Fit | Mercedes Juarez | 2007–11 |
| Joe Flanigan [21] | Neil Byrne | 2019–20 |
| Eliza Frakes | Julie | 2023 |
| Betsy Franco | Betsy Frank | 2010, 2013–14 |
| James Franco | Franco | 2009–12 |
| Margarita Franco | Dolores Santiago | 1994 |
| Liam and Oliver Friedy | Rocco Falconeri | 2014–15 |
| Kelly Frye | Ivy Gatling | 2014–15 |
| Courtney Fulk [a] | Josslyn Jacks | 2023–24 |
| John Gabriel | Teddy Holmes | 1972–73 |
| Holly Gagnier | Jennifer Smith | 2015, 2022 |
| Max Gail | Mike Corbin | 2018–21 |
| Patrick Gallagher [23] | Prison guard | 2017 |
| Don Galloway | Buzz Stryker | 1985–1987 |
| Guy Gansert [24] | Geoffrey | 2025 |
| Leif Gantvoort [25] [26] | Carson | 2018 |
| Priscilla Garita | Lupe | 2011 |
| Harmony Miller | 2022 | |
| Zachary Garred | Levi Dunkleman | 2014 |
| Drew Garrett | Michael Corinthos | 2009–10 |
| David Gautreaux | Peter Harrell, Sr. | 2014 |
| George Gaynes | Frank Smith | 1980 |
| Anthony Geary | Luke Spencer | 1978–84, 1993–2015, 2017 |
| Bill Eckert | 1991–93 | |
| Cesar Faison | 2014 | |
| Tim Spencer | 2015 | |
| Jason Gerhardt | Cooper Barrett | 2007–08 |
| Jean Glaudé | Waiter | 1967 |
| Committee Member 2 | 1994 | |
| Thomas Anderson | 2013 | |
| Blake Gibbons | Coleman Ratcliffe | 2002–12, 2014 |
| Nigel Gibbs | Marcus Godfrey | 2018–20 |
| Mark Goddard | Derek Barrington | 1984–86 |
| Gerald Gordon | Mark Dante | 1976–78, 1982–83 |
| Amy Grabow | Rachel Adair | 2005 |
| Juliet Grainger | Lila Quartermaine | 2003–04 |
| Nathanyael Gray | Mason Gatlin | 2022–23 [27] |
| Mary-Pat Green | Nurse Fletcher | 2012 |
| David Greenman | Danny McCall | 2005–06 |
| Michael Gregory | Rick Webber | 1976–78 |
| David Groh | D. L. Brock | 1983–85 |
| Ben Guillory | David Walters | 2013 |
| Jennifer Guthrie | Dawn Winthrop | 1990–91 |
| Joyce Guy | Betty | 2011 |
| Phyllis Caulfield | 2020–2023 | |
| Ron Hale | Mike Corbin | 1995–10 |
| Carla Hall | Cook II | 2018 |
| Tamron Hall | Herself | 2019 |
| Courtney Halverson | Anna Donely | 2013 |
| Mark Hamill | Kent Murray | 1972–73 |
| George Hamilton [28] | Colonel Sanders | 2018 |
| Kim Hamilton | Tracy Adams | 1968–69 |
| Jennifer Hammon | Karen Wexler | 1997–99 |
| Peter Hansen | Lee Baldwin | 1965–86, 1989–90, 1992–2004 |
| Vanita Harbour | Dara Jensen | 1996–2003 |
| Eden Harker | Georgie Spinelli | 2023 |
| Adam J. Harrington | John Cates | 2024 |
| Glenn Walker Harris, Jr. | Sly Eckert | 1991–95 |
| Steve Richard Harris | Mikkos Cassadine | 2021 |
| Gregory Harrison | Gregory Chase | 2020–24 |
| Lindsay Hartley | Sam McCall | 2020, 2022, 2024 |
| Donald Patrick Harvey | Tom Baker | 2016 |
| Bob Hastings | Burt Ramsey | 1978–86 |
| Billie Hayes | Agent Brighton O'Reilly | 1981, 1985 |
| Ron Hayes | Phil Brewer | 1967 |
| Patricia Healy | Tammy Hansen | 1998–2000 |
| Gina Hecht [29] | Rachel Lasser | 2015–19 |
| Elizabeth Hendrickson | Margaux Dawson | 2018–19 |
| Briana Nicole Henry | Jordan Ashford | 2018–21 |
| 1920 voter | 2020 | |
| Kristin Herrera | Lourdes Del Torro | 2004–08 |
| Brighton Hertford | B.J. Jones | 1986–94, 2024 |
| Martin Hewitt | Steven Webber | 1979–81 |
| Shelby Hiatt | Jane Harland | 1968–75 |
| Alice Hirson | Mrs Van Gelder | 1982 |
| Evan Hofer | Dex Heller | 2022–24 [30] |
| Kara and Shelby Hoffman | Kristina Davis | 2003 |
| Robert Hogan | Phil Brewer | 1966 |
| Burt Marshall | 1973 | |
| Gerald Hopkins | A. J. Quartermaine | 1991–92 |
| Leslie Horan | Miranda Jameson | 1996–97 |
| Gavin Houston | Sly Thomas | 2010 |
| Zeke Robinson | 2023 | |
| Roger Howarth | Todd Manning | 2012–13 |
| Franco Baldwin | 2013–21 | |
| Drew Cain | 2019 | |
| Austin Gatlin-Holt | 2021–23 [31] | |
| Tina Huang | Linda Chu | 2013–14 |
| Janet Hubert | Yvonne Godfrey | 2018–20 |
| Craig Huebing | Phil Brewer | 1967 |
| Peter Taylor | 1969–79 | |
| Van Hughes | Cole Thornhart | 2012 |
| Duncan Hursley | Mechanic Bill | 2014 |
| Rif Hutton | Lenny Caulfield | 2021–22 |
| Julio Iglesias | Himself | 1994 |
| Mele Ihara | Reiko Finn | 2022 |
| Annie Ilonzeh | Maya Ward | 2010–11 |
| John Ingle | Edward Quartermaine | 1993–2004, 2006–12 |
| Steve Inwood | Moreno | Unknown |
| Conor Jackson | Physical Therapist | 2009 |
| Jonathan Jackson | Lucky Spencer | 1993–1999, 2009–2011, 2015, 2024–2025 |
| Titus Jackson | Aiden Spencer | 2011–12 |
| Kevin and Michael Jacobson | Dillon Quartermaine | 1992–93 |
| Donnie Jeffcoat | Craig | 1990 |
| Anne Jeffreys | Amanda Barrington | 1984–2004 |
| Johnny Jensen | Scott Baldwin | 1974–75 |
| Mikey Jerome | Eddie | 2021 |
| Arte Johnson | Finian O'Toole | 1991–92 |
| Sarah Johnson | Josslyn Jacks | 2012–13 |
| Ashley Jones | Parker Forsyth | 2016–17 |
| Asante Jones | Marcus Taggert | 2020–22 |
| Christine Jones | Tracy Quartermaine | 1989 |
| Jamison Jones | William Peavy | 2004–05 |
| Brady Bevin | 2016 | |
| Warren Kirk | 2020 | |
| Shirley Jones | Mrs McClain | 2014 |
| Kathryn Joosten | Ida Warren | 2002–03 |
| Bobbi Jordan | Terri Webber | 1976–77 |
| Patrick J Gibbons Jr. | Wyatt Hoover | 2018–19, 2021 |
| Stanley Kamel | Cody McCall | 2003–04 |
| Sean Kanan | A. J. Quartermaine | 1993–97, 2012–14 |
| Holly Kaplan | Monica Quartermaine | 2022 |
| Casey Kasem | Jack Collins | 1982 |
| Lesli Kay | Lois Cerullo | 2004–05 |
| Stephen Kay | Reginald Jennings | 1992–2004 |
| Braiden and Dylan Kazowski | Danny Morgan | 2015–16 |
| Robert Kelker-Kelly | Stavros Cassadine | 2001–03, 2013–14 |
| Jim Kelly [32] | Himself | 1992 |
| Sandy Kenyon | Guard | 2015 |
| Shell Kepler | Amy Vining | 1979–2002 |
| B.B. King | Himself | 1995 |
| Ted King | Luis Alcazar | 2002 |
| Lorenzo Alcazar | 2003–07 | |
| Nick Kiriazis | Ric Lansing | 2007 |
| Kodi Kitchen | Maggie Wurth | 2011–12 |
| Jeff Kober | Cyrus Renault | 2020–2025 |
| Walter Koenig | Charlie Turner | 1963 |
| Alla Korot | Nurse Darya | 2017 |
| Holiday Mia Kriegel | Molly Lansing | 2023 |
| Jaxon and Jakob Kring | Danny Morgan | 2012–14 |
| Ilene Kristen | Delia Ryan | 2013–15 |
| Michael Blake Kruse | Rory Cabrera | 2022 |
| Peter Kwong | The Psychiatrist | 2004 |
| Mary Laina | Reporter | 2000–02 |
| Sarah Laine | Sarah Webber | 2002 |
| Shayne Lamas | Carly Corinthos | 2003–05 |
| André Landzaat | Tony Cassadine | 1981 |
| Briana Lane | Brook Lynn Ashton | 2020, 2022 |
| Archie Lang | Forbes | 1982 |
| George Lako | Frankie | 2015–16 |
| Chloe Lanier | Pat Spencer | 2015 |
| Nelle Benson [33] | 2016–20, 2022 | |
| Georganne LaPiere [34] | Heather Webber | 1976–77 |
| Karleigh Larson | Josslyn Jacks | 2009–12 |
| Ken Lally | Greg | 2002-03 |
| Eva LaRue | Natalia Rogers-Ramirez | 2024–2025 |
| Robert LaSardo | Manny Ruiz | 2005–2006 |
| Mateo Ruiz | 2006–2007 | |
| Carol Lawrence | Angela Eckart | 1991–93 |
| Mark Lawson | Dustin Phillips | 2019–20 |
| George Lazenby | Reginald Durban | 1982 |
| Tiana Le | Trina Robinson | 2017–18 |
| Michael Learned | Shirley Smith | 2010 |
| Anna Lee | Lila Quartermaine | 1978–2003 |
| David S. Lee | Winston Rudge | 2016–17, 2020 |
| Andrew T. Lee | Marty Brown | 2006–09 |
| Damien Leeke | Marshall Ashford | 2022 |
| Edie Lehmann | Katherine Delafield | 1988–90 |
| Colby Lemmo | Holly Sutton-Scorpio | 2022 |
| Ella Lentini | Betty Rutherford | 2023 |
| Adrianne León | Brook Lynn Ashton | 2004–06, 2010–11 |
| Lindze Letherman | Georgie Jones | 2002–07, 2010, 2013, 2018 |
| David Lewis | Edward Quartermaine | 1978–93 |
| Judy Lewis | Barbara Vining | 1975–76, 1978 |
| Brit Lind | Miss Bixby | 1988 |
| Jen Lilley | Maxie Jones | 2011–12 |
| Natalia Livingston | Emily Quartermaine | 2003–09, 2013–14 |
| Rebecca Shaw | 2009 | |
| Bradley Lockerman | Casey Rogers | 1990 |
| Shep Casey | 1990 | |
| June Lockhart | Maria | 1991–94 |
| Samantha Logan | Taylor DuBois | 2013 |
| Mitch Longley | Matt Harmon | 1997–99 |
| Eva Longoria | Brenda Barrett Lookalike | 2000 |
| Jacqueline Grace Lopez [35] | unnamed babysitter | 2015–16 |
| Blaze | 2022–24 | |
| Charles and Ethan Losie | Rocco Falconeri | 2015–16 |
| Jophielle Love | Violet Finn | 2019–24 [36] |
| Christine Lozano | Christi Limg | 2012–18 |
| Florencia Lozano | Téa Delgado | 2012 |
| Henry Lubatti | Danny McCall | 2004 |
| Keye Luke | The Ancient One | 1985 |
| Joey Luthman | Luke Spencer | 2015 |
| Bill Eckert | 2015 | |
| Stephen Macht | Trevor Lansing | 2007–09 |
| Elizabeth MacRae | Meg Baldwin | 1969–73 |
| Sheila MacRae | Madelyn Richmond | 1991 |
| Martha Madison | Elizabeth Webber | 2011 |
| Christian Malmin | Fred Gray | 2016–17 |
| Rio Mangini | Oscar Nero | 2017 |
| Randolph Mantooth | Richard Halifax | 1991–93 |
| Mary Mara | Selma | 2014 |
| Gregory Marcel | Orderly Gordon | 2018 |
| Vanessa Marcil | Brenda Barrett | 1992–98, 2002–03, 2010–11, 2013 |
| Lisa Marie | Jennifer Smith | 1980 |
| Joe Marinelli | Joseph Sorel | 1999-2001 |
| Marcella Markham | Beatrice LeSeur | 1984 |
| Meghan Markle | Jill | 2002 |
| Ronnie Marmo | Ronnie Dimestico | 2009–12 |
| Matt Marraccini | Jesse Beaudry | 2005–06 |
| Jason Marsden | A. J. Quartermaine | 1986–88 |
| Mia Martin | Kristin Bergman | 2002 |
| Ricky Martin | Miguel Morez | 1994–96 |
| A Martinez | Roy DiLucca | 1999–02 |
| Cyndi Martino | Nurse | 2000 |
| John Martinuzzi | Stavros Cassadine | 1983 |
| Joseph Mascolo | Nicholas Van Buren | 1989 |
| Kerwin Mathews | Duncan Stewart | 1972 |
| Lee Mathis | John Hanley | 1995–96 |
| Eddie Matos | Pete Marquez | 2006–07 |
| DeLane Matthews | Janine Matthews | 2001–03 |
| Robin Mattson | Heather Webber | 1980–1983, 2004, 2012–2016 |
| Helena Mattsson | Sasha Gilmore | 2022 |
| Sofia Mattsson | Sasha Gilmore | 2018–2025 |
| Brad Maule | Tony Jones | 1984–2006, 2019 |
| Richard Mawe | Hospital Review Board Chairman | 2015 |
| Frank Maxwell | Dan Rooney | 1978–90 |
| Heather Mazur | Eileen Ashby | 2021–23 |
| Diane McBain | Claire Howard | 1988 |
| Amelie McClain | Charlotte Cassadine | 2021–23 |
| Leigh McCloskey | Damian Smith | 1993–96 |
| Judith McConnell | Augusta McLeod | 1973–75 |
| Patty McCormack | Monica Quartermaine | 2018 |
| Peyton McCormick | Penny | 2013 |
| Grayson McCouch | Kyle Sloane | 2015 |
| Kimberly McCullough | Robin Scorpio | 1985–2000, 2004–18, 2021 |
| Maura McGiveney | Audrey Hardy | 1971 |
| Beverlee McKinsey | Myrna Slaughter | 1994 |
| Kurt McKinney | Ned Ashton | 1988–91 |
| Amelie McLain | Charlotte Cassadine | 2021–23 |
| Coby Ryan McLaughlin | Shiloh | 2018–19 |
| Emily McLaughlin | Jessie Brewer | 1963–91 |
| Cade McWatt | Cameron Spencer | 2018 |
| Jeffrey Meek | Thomas Dade | 2002 |
| Ron Melendez | Andy Archer | 2007–09 |
| Lilly Melgar | Lily Rivera Corinthos | 1994–96, 2001, 2003 |
| Marcella Montoya | 2003 | |
| Bridgit Mendler | Lulu's Dream Daughter | 2006 |
| Dawn Merrick | Samantha Welles | 1985–89 |
| Charles Mesure | Jack Brennan | 2023–2025 |
| Katie Mewes | Bobbie Spencer | 2015 |
| Krys Meyer | TJ Ashford | 2012 |
| Robert Miano | Joe Scully Sr. | 1995 |
| Amanda Michalka | Ashley B | 2004 |
| Sydney Mikayla | Trina Robinson | 2019–22 |
| Allison Miller | Tracy Quartermaine | 2006 |
| Billy Miller | Jake Doe | 2014–15 |
| Jason Morgan | 2014–17 | |
| Drew Cain | 2017–19 | |
| J. Robin Miller | Lydia Karenin | 2003 |
| Mark Miller | Randy Washburn | 1965 |
| Alley Mills | Heather Webber | 2022–24 |
| Donna Mills | Madeline Reeves | 2014–2015, 2018 |
| Melanie Minichino | Kristin Bergman | 2021 |
| Mary Ann Mobley | Jonelle Andrews | 1979 |
| Kelly Monaco | Sam McCall | 2003–24 |
| Alicia Montenegro | 2005 | |
| Julie Mond | Lisa Niles | 2009 |
| Anthony Montgomery | Aaron | 2011 |
| Andre Maddox | 2015–19, 2022 | |
| Elizabeth Montgomery | Elizabeth Clarke Brown | 1986; 1991–94 |
| Rebeka Montoya | Delores Padilla | 2011–12 |
| Christian Monzon | Eddie Cabrera | 2012 |
| Lynne Moody | Florence Campbell | 2000–02 |
| Chris Moore | Himself | 1992 |
| Demi Moore | Jackie Templeton | 1982–84 |
| Camilla More | Anna Devane | 1991–92 |
| Debbi Morgan | Ellen Burgess | 1997–98 |
| Lindsey Morgan | Kristina Davis | 2012–13 |
| Ann Morrison | Peggy Nelson | 1971 |
| M'fundo Morrison | Justus Ward | 2003–06 |
| Ronn Moss | Himself | 2014 |
| Oliver Muirhead [37] | Larry Ashton | 2017 |
| Mandy Musgrave | Carol Lockhart | 2019 |
| Manuel Nardi | Jackie | 2006 |
| Guy Nardulli | Pete | 2016 |
| Hugo Napier | Larry Ashton | 1988–89, 1991–92, 2014, 2016 |
| Jaime Ray Newman | Kristina Cassadine | 2001–03 |
| Robert Newman | Prescott Harrell | 1985 |
| Stephen Nichols | Stefan Cassadine | 1996–2003 |
| James Nigbor | Jake Spencer | 2009–11 |
| Leonard Nimoy | Bernie Smith | 1963 |
| Minae Noji | Kelly Lee | 2006–12, 2015–16 |
| Hannah Nordberg | Josslyn Jacks | 2014–15 |
| Jay North | Al Barker | 1981 |
| Noshir Dalal | Raj | 2015, 2019 |
| Mary O'Brien | Heather Webber | 1977–79 |
| Alyshia Ochse | Irina Cassadine | 2011–12 |
| John O'Hurley | Greg Bennett | 1992 |
| Ronan O'Reilly | 2010 | |
| Jonathan Ohye | Dr Andy | 2015–19 |
| Agnes Olech | Larisa | 2017 |
| Ron Ostrow | Pilot | 1996–2001 |
| Dr Austin | 2008 | |
| David Otunga | Himself | 2014 |
| Janis Paige | Aunt Iona Huntington | 1980-90 |
| Johnny Palermo | Bus Boy | 2005 |
| Vinnie | 2007 | |
| Ken Parham | Fireman Hawkeye | 1998–99 |
| Jeffrey Vincent Parise | Carlos Rivera | 2013–16 |
| Joe Rivera | 2016 | |
| Palmer and Poe Parker [38] | Scout Cain | 2017–19 |
| Nathan Parsons | Ethan Lovett | 2009–13, 2015, 2020 |
| Rick Pasqualone | Vincent Marino | 2018 |
| Vincent Pastore | Maximus Giambetti | 2008 |
| Alina Patra | Susan Hornsby | 2016 |
| Ciera Payton | Grace | 2017 |
| Lindsey Pearlman | Margaret McMorris | 2020 |
| Andrea Pearson | Gia Campbell | 2002–03 |
| Nia Peeples | Carla Escobar | 1983–84 |
| Thaao Penghlis | Victor Cassadine | 1981, 2014 |
| George Pennacchio | George | 2013–18 |
| Christopher Pennock | Mitch Williams | 1979–80 |
| Melissa Peterman | Mel | 2015 |
| Beth Peters | Agnes Whitaker | 1982-84 |
| Joseph C. Phillips | Justus Ward | 1994–98 |
| Jay Pickett | Lorenzo Alcazar | 2006 |
| David Harper | 2007–08 | |
| Cara Pifko | Louise Addison | 2009 |
| Edward Platt | Dr Miller | 1963 |
| Avery Kristen Pohl | Esme Prince | 2021–24 |
| Larry Poindexter | Asher Thomas | 2005 |
| Ely Pouget | Jeannette Marino | 2018 |
| Brittney Powell | Summer Halloway | 2002–03 |
| Haley Pullos | Molly Lansing | 2009–23 |
| Susan Pratt | Anne Logan | 1978–82 |
| Erin Hershey Presley | Alison Barrington | 2013 |
| Cynthia Preston | Faith Rosco | 2002–05 |
| Nicholas Pryor | Victor Collins | 1997–2003 |
| Teddy Quinn | Scott Baldwin | 1966 |
| Alan Rachins | Judge James Horowitz | 2016-18 |
| Brooke Radding | Brook Lynn Ashton | 1996–2001 |
| Patsy Rahn | Monica Quartermaine | 1976–77 |
| Marisa Ramirez | Gia Campbell | 2000–02 |
| Trish Ramish | Herself | 2011, 2019 |
| Gail Ramsey | Susan Moore | 1978–83 |
| Wes Ramsey | Peter August | 2017–22 |
| Lak Rana | Lak Rashi | 2013 |
| Lou Rawls | Himself | 1995 |
| Jen Ray | Chelsea Lambas | 2019 |
| James Read | Gregory Chase | 2018 |
| Scott Reeves | Steven Webber | 2009–13, 2024 |
| Caitlin Reilly | Anna Donely | 2021 |
| John Reilly | Sean Donely | 1984–95, 2013 |
| Peter Renaday | John Jacks | 1996–2003, 2012 |
| Robyn Richards | Maxie Jones | 1993–2004 |
| Cheryl Richardson | Jenny Eckert | 1991–94, 1996 |
| Tequan Richmond | TJ Ashford | 2012–18 |
| Matt Riedy | Matthew Mayes | 2016 |
| Tristan Riggs | Aiden Spencer | 2024 |
| Robin Riker | Naomi Dreyfus | 2016 |
| Zakary Risinger [39] | Danny Morgan | 2021 |
| Renie Rivas | Gallery assistant | 2017 |
| Alexia Robinson | Meg Lawson | 1990–94 |
| Chris Robinson | Rick Webber | 1978–86, 2002, 2013 |
| Sebastian Roché | Jerry Jacks | 2007–10, 2012–15 |
| Michael Rodrick | Seth Baker | 2016 |
| Kali Rodriguez | Kristina Davis | 2005–2008 |
| Tristan Rogers | Robert Scorpio | 1980–1992, 1995, 2006, 2008, 2012–2016, 2018–2025 |
| Willa Rose | Nelle Benson | 2020 |
| Ricco Ross | Sterling Robinson | 2023 |
| Paul Rosilli | David Grey | 1981–82 |
| Caden and Corben Rothweiler | Danny Morgan | 2014–15 |
| Curtis & James Rufca [40] | James West | 2019 |
| Tim Russ | Dr Trent | 2006–07 |
| Richard Rust | James Vining | 1975 |
| James Ryan | Ethan Lovett | 2023 |
| Mitchell Ryan | Frank Smith | 1993–94 |
| Roz Ryan | Esther Love | 2012 |
| Emme Rylan | Lulu Spencer | 2013–20 |
| Antonio Sabàto Jr. | Jagger Cates | 1992–95 |
| Dahlia Salem | Claire Walsh | 2010–11 |
| Emma Samms | Holly Sutton-Scorpio | 1982–1985, 1992–1993, 2006, 2009, 2012–2013, 2015, 2020, 2022–2024 |
| Paloma Stuart | 1992–1993 | |
| David Sampen | Photographer/ Port Charles Resident | 2014–19 |
| Brytni Sarpy | Valerie Spencer | 2015–19 |
| Richard Sarradet | Howard Lansing | 1978–81 |
| Paul Satterfield | Paul Hornsby | 1991–94 |
| Michael Saucedo | Juan Santiago | 1999–01, 2013–14 |
| Paul Savoir | Tom Baldwin | 1967–72 |
| Owen Saxon [41] | Carson's Henchman | 2018 |
| Travis Schuldt | Dr. Zajac | 2017 |
| Brad Schmidt | Brando Corbin | 2022 |
| Book | 2022–23 | |
| Coltin Scott | Nikolas Cassadine | 1999–03 |
| Ignacio Serricchio | Diego Alcazar | 2004–06, 2008 |
| Aaron Seville | Bradley Ward | 1994–96 |
| Paula Shaw | Records Nurse | 1981 |
| O.R. Nursing Supervisor | 1982 | |
| Monti Sharp | Justus Ward | 1998–99 |
| Charles Shaughnessy | Alistair Durban | 1984 |
| Victor Cassadine | 2021–23 | |
| Cari Shayne | Karen Wexler | 1992–94 |
| Doug Sheehan | Joe Kelly | 1979–82 |
| Blake Sheldon | Hale Garrett | 2016 |
| Graham Shiels | Cody Paul | 2007–08 |
| James Sikking | James Hobart | 1973–76 |
| Londyn Silzer | Bailey | 2017 |
| Richard Simmons | Himself | 1979–82, 2013 |
| Peggy Sinclair | Sister Ellen Chapman | 1972–73 |
| Brooklyn Rae Silzer | Emma Drake | 2011–18, 2020 |
| Jennifer Sky | Sarah Webber | 1997–98 |
| Tava Smiley | Chloe Morgan | 1999–2001 |
| Brooke Anne Smith | Molly Lansing | 2023 |
| Emma and Sarah Smith | Kristina Davis | 2003–05 |
| Hillary B. Smith | Nora Buchanan | 2017, 2019 |
| Justin Smith | Holt | 2016 |
| Rena Sofer | Lois Cerullo | 1993–1997, 2023–2025 |
| Rick Springfield | Noah Drake | 1981–83, 2005–08, 2012–13 |
| Eli Love | 2007–08 | |
| Himself | 2013 | |
| Nick Stabile | Nikolas Cassadine | 2016 |
| Kelly Stables | Bobbie Spencer | 2003 |
| Michelle Stafford | Nina Reeves | 2014–19 |
| John Stamos | Blackie Parrish | 1982–84 |
| Darby Stanchfield | Amelia Joffe | 2007 |
| Jonathan Stanley | Billy Pryce | 2019 |
| Anthony Starke | Kevin Collins | 2015 |
| Valerie Starrett | Diana Taylor | 1969–77 |
| Richard Steinmetz | Joe Scully, Jr. | 2012 |
| Stella Stevens | Jake | 1996-99 |
| Danica Stewart | Maxie Jones | 2002 |
| Garren Stitt | Oscar Nero | 2017–19 |
| Julian Stone | Jerry Jacks | 1998–99 |
| Deborah Strang | Betsy Frank | 2017–18 |
| Sally Struthers | Jennifer Smith | 2002 |
| Anna Stuart | Gina Dante-Lansing | 1977–78 |
| Gloria Stuart | Catherine Flynn | 2002–03 |
| Katie Stuart | Sage Alcazar | 2003–04 |
| Coleen Sullivan | Herself | 2018 |
| Kelly Sullivan | Connie Falconeri | 2011–14 |
| Liam Sullivan | Roy Lansing | 1963–64 |
| Dr Wallace | 1988 | |
| Michael Sutton | Stone Cates | 1993–95, 2010, 2017 |
| Gable Swanlund | Alexis Davis | 2021 |
| George Takei | Mr Diem | 1985 |
| Amber Tamblyn | Emily Quartermaine | 1995–01 |
| Philip Tanzini | Jeremy Logan | 1978–82 |
| Barbara Tarbuck | Jane Jacks | 1996–2010 |
| Milt Tarver | Justice of the Peace | 2000 |
| Elizabeth Taylor | Helena Cassadine | 1981 |
| Jana Taylor | Angie Costello-Weeks | 1963–65, 1993 |
| Roy Thinnes | Phil Brewer | 1963–66 |
| Jason Thompson | Patrick Drake | 2005–16 |
| Steve Hardy | 2015 | |
| Pam Tillis | Herself | 1998 |
| Marcus Toji | Brad Cooper | 2013 |
| Constance Towers | Helena Cassadine | 1997–2007, 2009–17, 2019–20, 2022–23 |
| Daniel J. Travanti | Spence Andrews | 1979 |
| Les Tremayne | Edward Quartermaine | 1987–88 |
| Craig Tsuyumine | Dr Hillier | 2001 |
| Clerk | 2017 | |
| Jessica Tuck | Cassandra Pierce | 2017–19 |
| Janine Turner | Laura Templeton | 1982–83 |
| Michael Tylo | Charlie Prince | 1989 |
| Daya Vaidya | Martina Morales | 2017 |
| Erik Valdez | Trey Mitchell | 2012–13 |
| Chris Van Etten | Chet Driscoll | 2017–19, 2022 |
| Greg Vaughan | Lucky Spencer | 2003–09 |
| Reginald VelJohnson | Reverend Winston Love | 2012 |
| Nick Viall [42] [43] [44] | Himself | 2018 |
| Meredith Vieira | Bree Flanders | 2003, 2012 |
| Anthony Vitale | Aldo | 2015–16 |
| Danielle von Zerneck | Louisa "Lou" Swenson | 1983–84 |
| Lisa Vultaggio | Hannah Scott | 1999–2001 |
| Johnny Wactor | Brando Corbin | 2020–22 |
| Catherine Wadkins | Mary Bishop | 2004 |
| Chuck Wagner | Randall Thompson | 1981-1982 |
| Jack Wagner | Frisco Jones | 1984–91, 1994–95, 2013 |
| Tonja Walker | Olivia St. John | 1988–90, 2017 |
| Jamil Walker Smith | Jeffrey Scribner | 2014 |
| Braden Walkes | Cameron Spencer | 2006–2012 |
| Lucille Wall | Lucille Weeks | 1963–76, 1982 |
| David Wallace | Tom Hardy | 1987–93 |
| Dee Wallace | Pat Spencer | 2015 |
| Sydney Walsh | Maggie | 2021 |
| Kelsey Wang [45] | Daisy Kwan | 2018–20 |
| Burt Ward | Himself | 1991–94 |
| Megan Ward | Kate Howard | 2007–10, 2018, 2020 |
| Cari Ann Warder | Amy Vining | 1975 |
| Billy Warlock | A. J. Quartermaine | 1997–2003, 2005 |
| Lee Warrick | Mary Ellen Dante | 1976–77 |
| Tuc Watkins | Pierce Dorman | 1996–97 |
| Robert Palmer Watkins | Dillon Quartermaine | 2015–17 |
| Michael Watson | Decker Moss | 1989–91 |
| Kristina Wayborn | Greta Ingstorm | 1987–88 |
| TK Weaver | Danny Morgan | 2016–19 |
| Bruce Weitz | Anthony Zacchara | 2007–12 |
| Elmarie Wendel | Peg | 2008 |
| Annie Wersching | Amelia Joffe | 2007 |
| Adam West | Himself | 1991–94 |
| Martin West | Phil Brewer | 1967–75 |
| Justin Whalin | A. J. Quartermaine | 1989 |
| James Wheaton | Stahlman | 1978 |
| Johnny Whitaker | Scott Baldwin | 1965–66 |
| Betty White | Herself | 1991–94 |
| Dan White | Elijah Crowe | 2021 |
| Walt Willey | Jackson Montgomery | 2023 |
| Barry Williams | Hannibal | 1984 |
| Bergen Williams | Alice Gunderson | 2001–15 |
| Billy Dee Williams | Toussaint Dubois | 2009 |
| Stephanie Williams | Simone Ravelle Hardy | 1990–93 |
| Bree Williamson | Claudette Beaulieu | 2016–17 |
| Alicia Leigh Willis [46] | Courtney Matthews | 2001–06, 2015, 2020 |
| Chandra Wilson | Tina Estrada [47] | 2014 |
| Linda Massey [48] | 2018 | |
| Sydney Val Jean [49] | 2019, 2023 | |
| Emily Wilson | Ellie Trout | 2012–16, 2022 |
| Guy Wilson | Luke Spencer | 2006 |
| Lucky Spencer [50] | 2025 | |
| Marie Wilson | Karen Wexler | 1999–2003 |
| Jason Wingreen | Judge Mattson | 1991 |
| Time Winters | Arthur Cabot | 2019 |
| Sherilyn Wolter | Celia Quartermaine | 1983–86 |
| Lesley Woods | Edna Hadley | 1977–78, 1980 |
| Kari Wührer | Reese Marshall | 2005 |
| Sharon Wyatt | Tiffany Donely | 1981–84, 1986–95, 2021 |
| Meg Wyllie | Doris Roach | 1975 |
| Hester Frumpkin | 1982 | |
| Lila Quartermaine | 1994 | |
| Anne Wyndham | Caroline Murray | 1972–75 |
| Gwendoline Yeo | Kelly Lee | 2006 |
| Jacob Young | Lucky Spencer | 2000–03 |
| Tony Young | Herb Clark | 1963 |
| William Allen Young | David Walters | 2014–15, 2019−20 |
| Gregory Zarian | Julius | 2007–08 |
| Maysoon Zayid | Zahra Amir | 2019–20 |
| Joe Zee [51] [52] | Himself | 2016 |
| Jacklyn Zeman | Bobbie Spencer | 1977–2010, 2013–23 |
Dan Buran, who has played the role on and off since 2020, is leaving the ABC soap, as reported in this week's issue of Soap Opera Digest . As of yet, there is no word if he'll turn up again in the future.
{{cite web}}: CS1 maint: location (link)