List of restriction enzyme cutting sites: A

Main articles: List of restriction enzyme cutting sites and Restriction enzyme

Legend of nucleobases
Code	Nucleotide represented
A	Adenine (A)
C	Cytosine (C)
G	Guanine (G)
T	Thymine (T)
N	A, C, G or T
M	A or C
R	A or G
W	A or T
Y	C or T
S	C or G
K	G or T
H	A, C or T
B	C, G or T
V	A, C or G
D	A, G or T

This article contains a list of restriction enzymes whose names start with A and have a clearly defined cutting site.

The following information is given for each enzyme:

• Name of Restriction Enzyme : Accepted name of the molecule, according to the internationally adopted nomenclature, ^{[1] [2]} and bibliographical references. Note: When alphabetizing, enzymes are first ordered alphabetically by the acronyms (everything before the roman numeral); then enzymes of a given acronym are ordered alphabetically by the roman numeral, treating the numeral as a number and not a string of letters. This helps keep the entries ordered hierarchically while also alphabetic.(Further reading: see the section "Nomenclature" in the article "Restriction enzyme".)
• PDB code: Code used to identify the structure of a protein in the PDB database of protein structures. The 3D atomic structure of a protein provides highly valuable information to understand the intimate details of its mechanism of action. ^{[3] [4]}
• REBASE Number: Number used to identify restriction enzymes in the REBASE restriction enzyme database. This database includes important information about the enzyme such as Recognition sequence, source, and Isoschizomers, as well as other data, such as the commercial suppliers of the enzyme.
• Source: Organism that naturally produces the enzyme.
• Recognition sequence : Sequence of DNA recognized by the enzyme and to which it specifically binds.
• Cut: Displays the cut site and pattern and products of the cut. The recognition sequence and the cut site usually match, but sometimes the cut site can be dozens of nucleotides away from the recognition site. ^{[5] [6]}
• Isoschizomers and neoschizomers : An isoschizomer is a restriction enzyme that recognizes the same sequence as another. A neoschizomer is a special type of isoschizomer that recognizes the same sequence as another, but cuts in a different manner. A maximum number of 8–10 most common isoschizomers are indicated for every enzyme but there may be many more. Neoschizomers are shown in bold and green color font (e.g.: BamHI). When "None as of [date]" is indicated, that means that there were no registered isoschizomers in the databases on that date with a clearly defined cutting site. Isoschizomers indicated in white font and grey background correspond to enzymes not listed in the current lists, as in this not listed enzyme:  Abc123I 

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Restriction enzymes

A

Enzyme	PDB code	REBASE Number	Source	Recognition sequence	Cut	Isoschizomers
AaaI		1	Acetobacter aceti	5' CGGCCG 3' GCCGGC	5' ---C   GGCCG--- 3' 3' ---GCCGG   C--- 5'	BseX3I, BstZI, EagI, EclXI, Eco52I, SenPT16I, XmaIII
AagI		4	Achromobacter agile	5' ATCGAT 3' TAGCTA	5' ---AT   CGAT--- 3' 3' ---TAGC   TA--- 5'	BanIII, BavCI, Bsa29I, BseCI, BspDI, Bsu15I, BsuTUI, ClaI
AanI		15358	Arthrobacter aurescens RFL2	5' TTATAA 3' AATATT	5' ---TTA   TAA--- 3' 3' ---AAT   ATT--- 5'	PsiI, Csp1BORF7380P
AarI [7]		2892	Arthrobacter aurescens SS2-322	5' CACCTGC 3' GTGGACG	5' ---CACCTGCN3N   NNNN--- 3' 3' ---GTGGACGN3NNNNN   --- 5'	PaqCI
AasI		5465	Arthrobacter aurescens RFL3	5' GACN6GTC 3' CTGN6CAG	5' ---GACNNNN   NNGTC--- 3' 3' ---CTGNN   NNNNCAG--- 5'	DrdI, DseDI
AatI [8]		6	Acetobacter aceti	5' AGGCCT 3' TCCGGA	5' ---AGG   CCT--- 3' 3' ---TCC   GGA--- 5'	AspMI, Eco147I,  Eco1524I,  PceI, Pme55I, SarI, Sru30DI, SteI
AatII [8] [9] [10] [11]		7	Acetobacter aceti	5' GACGTC 3' CTGCAG	5' ---GACGT   C--- 3' 3' ---C   TGCAG--- 5'	Ssp5230I, ZraI
AauI		3010	Arthrobacter aurescens	5' TGTACA 3' ACATGT	5' ---T   GTACA--- 3' 3' ---ACATG   T--- 5'	BsmRI,  Bsp1407I, BsrGI, BstAUI, Ssp4800I, SspBI
AbaI		3029	Azospirillum brasilense UQ 1796	5' TGATCA 3' ACTAGT	5' ---T   GATCA--- 3' 3' ---ACTAG   T--- 5'	BclI, BsiQI, BspXII, BstT7I, FbaI, Ksp22I,  ParI
AbeI		3097	Azotobacter beijerinckii Slo 54-028	5' CCTCAGC 3' GGAGTCG	5' ---CC   TCAGC--- 3' 3' ---GGAGT   CG--- 5'	BbvCI
AbrI		8	Azospirillum brasilense	5' CTCGAG 3' GAGCTC	5' ---C   TCGAG--- 3' 3' ---GAGCT   C--- 5'	BluI, BspAAI, BssHI, EscI, PaeR7I, SciI, Sfr274I, Sol10179I, StrI, TliI
AbsI		14594	Arthrobacter sp. 7M06	5' CCTCGAGG 3' GGAGCTCC	5' ---CC   TCGAGG--- 3' 3' ---GGAGCT   CC--- 5'	None as of 4 Apr. 2019
AccI [12] [13] [14] [15]		18	Acinetobacter calcoaceticus	5' GTMKAC 3' CAKMTG	5' ---GT   MKAC--- 3' 3' ---CAKM   TG--- 5'	FblI, XmiI
AccII [12] [16]		19	Acinetobacter calcoaceticus	5' CGCG 3' GCGC	5' ---CG   CG--- 3' 3' ---GC   GC--- 5'	Bsh1236I, Bsp50I, BstFNI, BstUI, MvnI, SelI, BceBI, BepI, Bpu95I
AccIII [17]		20	Acinetobacter calcoaceticus	5' TCCGGA 3' AGGCCT	5' ---T   CCGGA--- 3' 3' ---AGGCC   T--- 5'	Aor13HI, BbvAIII, BlfI, BseAI, BsiMI, BspEI, CauB3I, Kpn2I, MroI, PtaI
Acc16I		2638	Acinetobacter calcoaceticus 16	5' TGCGCA 3' ACGCGT	5' ---TGC   GCA--- 3' 3' ---ACG   CGT--- 5'	AosI, AviII, FdiII, FspI, MstI, NsbI, PamI, Pun14627I
Acc36I [18]		4162	Acinetobacter calcoaceticus 36	5' ACCTGC 3' TGGACG	5' ---ACCTGCN3N   NNNN--- 3' 3' ---TGGACGN3NNNNN   --- 5'	BfuAI, BspMI, BveI
Acc65I [19]		14	Acinetobacter calcoaceticus 65	5' GGTACC 3' CCATGG	5' ---G   GTACC--- 3' 3' ---CCATG   G--- 5'	AhaB8I, Asp718I, KpnI, SthI
Acc113I		2665	Acinetobacter calcoaceticus 113	5' AGTACT 3' TCATGA	5' ---AGT   ACT--- 3' 3' ---TCA   TGA--- 5'	AssI,  BmcAI, Bpa34I,  DpaI, Eco255I, RflFII, ScaI, ZrmI
AccB1I		15	Acinetobacter calcoaceticus B1	5' GGYRCC 3' CCRYGG	5' ---G   GYRCC--- 3' 3' ---CCRYG   G--- 5'	BanI, BbvBI, BshNI, BspT107I, Eco64I, HgiCI, HgiHI, MspB4I
AccB2I		2666	Acinetobacter calcoaceticus B2	5' RGCGCY 3' YCGCGR	5' ---RGCGC   Y--- 3' 3' ---Y   CGCGR--- 5'	BfoI, Bme142I, Bsp143II, BstH2I, HaeII, LpnI
AccB7I [20]		16	Acinetobacter calcoaceticus B7	5' CCAN5TGG 3' GGTN5ACC	5' ---CCANNNN   NTGG--- 3' 3' ---GGTN   NNNNACC--- 5'	AcpII, Asp10HII, BasI, Esp1396I, PflBI, PflMI, Van91I
AccBSI [21]		2733	Acinetobacter calcoaceticus BS	5' CCGCTC 3' GGCGAG	5' ---CCG   CTC--- 3' 3' ---GGC   GAG--- 5'	BsrBI, BstD102I, Bst31NI, MbiI
AccEBI		17	Acinetobacter calcoaceticus EBF 65/65	5' GGATCC 3' CCTAGG	5' ---G   GATCC--- 3' 3' ---CCTAG   G--- 5'	AsiI, BamHI, Bce751I, Bsp98I, BspAAIII, CelI, OkrAI, Uba4009I
AceI		2571	Anabaena cedrorum	5' GCWGC 3' CGWCG	5' ---G   CWGC--- 3' 3' ---CGWC   G--- 5'	ApeKI, SuiI, Taq52I, TseI
AceII		2570	Anabaena cedrorum	5' GCTAGC 3' CGATCG	5' ---GCTAG   C--- 3' 3' ---C   GATCG--- 5'	AsuNHI, BmtI,  BspOI, , LlaG2I, NheI, PstNHI
AceIII		2569	Anabaena cedrorum	5' CAGCTC 3' GTCGAG	5' ---CAGCTCN5N   NNNN--- 3' 3' ---GTCGAGN5NNNNN   --- 5'	— None as of May 2010 —
AciI [11] [22]		21	Arthrobacter citreus	5' CCGC 3' GGCG	5' ---C   CGC--- 3' 3' ---GGC   G--- 5'	SsiI
AclI [23]		2181	Acinetobacter calcoaceticus M4	5' AACGTT 3' TTGCAA	5' ---AA   CGTT--- 3' 3' ---TTGC   AA--- 5'	Psp1406I
AclNI		2667	Acinetobacter calcoaceticus N20	5' ACTAGT 3' TGATCA	5' ---A   CTAGT--- 3' 3' ---TGATC   A--- 5'	AhlI, BcuI, SpeI
AclWI		2668	Acinetobacter calcoaceticus W2131	5' GGATC 3' CCTAG	5' ---GGATCN3N   N--- 3' 3' ---CCTAGN3NN   --- 5'	AlwI, BinI,  BpuFI, BsrWI,  BspPI, BstH9I,  Bst31TI,  EacI,  Ral8I
AcoI		11822	Acinetobacter calcoaceticus	5' YGGCCR 3' RCCGGY	5' ---Y   GGCCR--- 3' 3' ---RCCGG   Y--- 5'	EaeI, Bfi89I, CfrI, EcoHK31I
AcpI		22	Acidiphilium cryptum 25H	5' TTCGAA 3' AAGCTT	5' ---TT   CGAA--- 3' 3' ---AAGC   TT--- 5'	Asp10HI, Bpu14I, Bsp119I, BstBI, Csp45I, FspII, MlaI, NspV, SspRFI
AcpII		23	Acidiphilium cryptum 25H	5' CCAN5TGG 3' GGTN5ACC	5' ---CCANNNN   NTGG--- 3' 3' ---GGTN   NNNNACC--- 5'	AccB7I, Asp10HII, BasI, Esp1396I, PflBI, PflMI, Van91I
AcrII		25	Anabaenopsis circularis	5' GGTNACC 3' CCANTGG	5' ---G   GTNACC--- 3' 3' ---CCANTG   G--- 5'	AspAI, Bse64I, BseT9I, BstEII, BstPI, Eco91I, EcoO65I, PspEI
AcsI [24]		2184	Arthrobacter citreus 310	5' RAATTY 3' YTTAAR	5' ---R   AATTY--- 3' 3' ---YTTAA   R--- 5'	ApoI,  CfaI,  FsiI, XapI
AcuI		5534	Acinetobacter calcoaceticus	5' CTGAAG 3' GACTTC	5' ---CTGAAGN13NNN   --- 3' 3' ---GACTTCN13N   NN--- 5'	BspKT5I, Eco57I
AcvI		5359	Aeromonas caviae	5' CACGTG 3' GTGCAC	5' ---CAC   GTG--- 3' 3' ---GTG   CAC--- 5'	BbrPI, BcoAI, Eco72I, PmaCI, PmlI, PspCI
AcyI [25]		31	Anabaena cylindrica	5' GRCGYC 3' CYGCRG	5' ---GR   CGYC--- 3' 3' ---CYGC   RG--- 5'	AhaII, AosII, BbiII, BsaHI, BstACI, Hin1I, HgiI, Hsp92I, Msp17I
AdeI		2991	Alcaligenes denitrificans Ss 3-028	5' CACNNNGTG 3' GTGNNNCAC	5' ---CACNNN   GTG--- 3' 3' ---GTG   NNNCAC--- 5'	BstIZ316I, DraIII
AeuI		33	Achromobacter eurydice	5' CCWGG 3' GGWCC	5' ---CC   WGG--- 3' 3' ---GGW   CC--- 5'	AglI, AjnI, BseBI, BstNI, BstOI, Bst2UI, EcoRII, SleI, SspAI
AfaI [26]		37	Acidiphilium facilis 28H	5' GTAC 3' CATG	5' ---GT   AC--- 3' 3' ---CA   TG--- 5'	Csp6I, CviQI, CviRII, HpyBI, PabI, PlaAII, RsaI, RsaNI
Afa16RI		34	Acidiphilium sp. 16R	5' CGATCG 3' GCTAGC	5' ---CGAT   CG--- 3' 3' ---GC   TAGC--- 5'	Afa22MI, BspCI, EagBI, MvrI, NblI, Ple19I, PvuI, Psu161I, RshI, XorII
Afa22MI		35	Acidocella facilis	5' CGATCG 3' GCTAGC	5' ---CGAT   CG--- 3' 3' ---GC   TAGC--- 5'	Afa16RI, BspCI, EagBI, ErhB9I, NblI, Ple19I, Psu161I, PvuI, RshI
AfeI [27]		2669	Alcaligenes faecalis T2774	5' AGCGCT 3' TCGCGA	5' ---AGC   GCT--- 3' 3' ---TCG   CGA--- 5'	AitI, Aor51H, Eco47III, FunI
AfiI		10489	Anoxybacillus flavithermus	5' CCN7GG 3' GGN7CC	5' ---CCNNNNN   NNGG--- 3' 3' ---GGNN   NNNNNCC--- 5'	Bsc4I, BseLI, BslI, BflI, Bsc107I, BsiYI, Bst22I
AflI [28]			Anabaena flos-aquae	5' GGWCC 3' CCWGG	5' ---G   GWCC--- 3' 3' ---CCWG   G--- 5'	Asp745I, BamNI, BcuAI, CauI, Csp68KI, DsaIV, Eco47I, SinI
AflII [28] [29] [30]		39	Anabaena flos-aquae	5' CTTAAG 3' GAATTC	5' ---C   TTAAG--- 3' 3' ---GAATT   C--- 5'	BfrI, BspTI, Bst98I, BstAFI, BstPZ740I, Esp4I, MspCI, Vha464I
AflIII [28] [10]		40	Anabaena flos-aquae	5' ACRYGT 3' TGYRCA	5' ---A   CRYGT--- 3' 3' ---TGYRC   A--- 5'	Asp90I
AgeI [11] [31]		42	Agrobacterium gelatinovorum	5' ACCGGT 3' TGGCCA	5' ---A   CCGGT--- 3' 3' ---TGGCC   A--- 5'	AsiAI, AsiGI, BshTI, CsiAI, CspAI, PinAI
AglI [32]		6652	Arthrobacter globiformis	5' CCWGG 3' GGWCC	5' ---CC   WGG--- 3' 3' ---GGW   CC--- 5'	AeuI, Bse16I, Bse17I, Bse24I, BshGI, EcoRII, SleI, SniI, SslI
AgsI			Agrococcus sp. 25	5' TTSAA 3' AASTT	5' ---TTS   AA--- 3' 5' ---AA   STT--- 3'	None as of 4 May 2019
AhaI		45	Alteromonas haloplanktis B8	5' CCSGG 3' GGSCC	5' ---CC   SGG--- 3' 3' ---GGS   CC--- 5'	AseII, BcnI,  BpuMI,  CauII, Eco1831I, EcoHI, HgiS22I, NciI
AhaII			Aphanothece halophytica	5' GRCGYC 3' CYGCRG	5' ---GR   CGYC--- 3' 3' ---CYGC   RG--- 5'	AcyI, AstWI, AsuIII, BsaHI, BstACI, Hin1I, HgiI, HgiDI, HgiHII, PamII
AhaIII [14] [29] [30] [33]			Aphanothece halophytica	5' TTTAAA 3' AAATTT	5' ---TTT   AAA--- 3' 3' ---AAA   TTT--- 5'	DraI, PauAII, SruI
AhaB8I			Aphanothece halophytica B8	5' GGTACC 3' CCATGG	5' ---G   GTACC--- 3' 3' ---CCATG   G--- 5'	Acc65I, Asp718I, KpnI, SthI
AhdI [34] [35]			Aeromonas hydrophila	5' GACN5GTC 3' CTGN5CAG	5' ---GACNNN   NNGTC--- 3' 3' ---CTGNN   NNNCAG--- 5'	AspEI,  BmeRI,  BspOVI, DriI, Eam1105I, EclHKI, NruGI
AhlI		4838	Alteromonas haloplanktis SP	5' ACTAGT 3' TGATCA	5' ---A   CTAGT--- 3' 3' ---TGATC   A--- 5'	AclNI, BcuI, SpeI
AhyI		49	Aeromonas hydrophila	5' CCCGGG 3' GGGCCC	5' ---C   CCGGG--- 3' 3' ---GGGCC   C--- 5'	Cfr9I, CfrJ4I, EaeAI, EclRI, PaeBI, SmaI, TspMI, XmaI, XmaCI
AitI		54	Aquaspirillum itersonii	5' AGCGCT 3' TCGCGA	5' ---AGC   GCT--- 3' 3' ---TCG   CGA--- 5'	AfeI, Aor51H, Eco47III, FunI
AjiI		10919	Acinetobacterjohnsonii RFL47	5' CACGTC 3' GTGCAG	5' ---CAC   GTC--- 3' 3' ---GTG   CAG--- 5'	BmgBI, BtrI
AjnI		7185	Acinetobacter johnsonii R2	5' CCWGG 3' GGWCC	5' ---   CCWGG--- 3' 3' ---GGWCC   --- 5'	AorI, ApaORI, ApyI, EcoRII, MvaI, Psp6I, PspGI, SleI, SspAI
AjoI		2604	Acinetobacter johnsonii 35	5' CTGCAG 3' GACGTC	5' ---CTGCA   G--- 3' 3' ---G   ACGTC--- 5'	ApiI, BloHII, BspMAI, CfrA4I, CfuII, PstI, SalPI, SflI, Srl5DI
AjuI		7740	Acinetobacter junii RFL46	5' GAAN7TTGG 3'CTTN7AACC	5' ---NNNNN   NN6GAAN7TTGGN5NNNNNN   --- 3' 3' ---   NNNNNNN6CTTN7AACCN5N   NNNNN--- 5'	None as of 28 Oct. 2020
AleI		5791	Aureobacterium liquefaciens	5' CACN4GTG 3' GTGN4CAC	5' ---CACNN   NNGTG--- 3' 3' ---GTGNN   NNCAC--- 5'	OliI
AlfI		6110	Acinetobacter lwoffii BH 32	5' GCAN6TGC 3' CGTN6ACG	5' ---GCAN6TGCN9NNN   --- 3' 3' ---CGTN6ACGN9N   NN--- 5'	None as of May 2010
AliI			Acetobacter liquefaciens	5' GGATCC 3' CCTAGG	5' ---G   GATCC--- 3' 3' ---CCTAG   G--- 5'	AccEBI, BamHI, Bce751I, Bsp98I, BspAAIII, Nsp29132II, Pfl8I
AliAJI		59	Acetobacter liquefaciens AJ 2881	5' CTGCAG 3' GACGTC	5' ---CTGCA   G--- 3' 3' ---G   ACGTC--- 5'	ApiI, Asp713I, BspMAI, CflI, CstI, MhaAI, PstI, SalPI, Sst12I, YenI
AloI [36] [37]		2812	Acinetobacter lwoffii Ks 4-8	5' GAACN6TCC 3' CTTGN6AGG	5' ---GAACN6TCCN6NNNNNN   --- 3' 3' ---CTTGN6AGGN6N   NNNNN--- 5'	None as of May 2010
AluI [12] [14] [38] [39] [40] [41]		61	Arthrobacter luteus	5' AGCT 3' TCGA	5' ---AG   CT--- 3' 3' ---TC   GA--- 5'	AluBI, MltI
AluBI		16189	Arthrobacter luteus B	5' AGCT 3' TCGA	5' ---AG   CT--- 3' 3' ---TC   GA--- 5'	AluI, MltI
AlwI		65	Acinetobacter lwoffii	5' GGATC 3' CCTAG	5' ---GGATCN3N   N--- 3' 3' ---CCTAGN3NN   --- 5'	AclWI, BinI, BspPI,  BsrWI,  BstH9I,  BthII, Bth617I,  EacI
Alw21I			Acinetobacter lwoffii RFL21	5' GWGCWC 3' CWCGWG	5' ---GWGCW   C--- 3' 3' ---C   WCGWG--- 5'	AspHI, Bbv12I, Bsh45I, BsiHKAI, Bsm6I,  HgiAI, MspV281I
Alw26I [42]		63	Acinetobacter lwoffii RFL26	5' GTCTC 3' CAGAG	5' ---GTCTCN   NNNN--- 3' 3' ---CAGAGNNNNN   --- 5'	BcoDI, BscQII,   BsmAI, BsoMAI,  BstMAI
Alw44I			Acinetobacter lwoffii RFL44	5' GTGCAC 3' CACGTG	5' ---G   TGCAC--- 3' 3' ---CACGT   G--- 5'	ApaLI, SnoI, VneI
AlwNI [43]			Acinetobacter lwoffii N	5' CAGNNNCTG 3' GTCNNNGAC	5' ---CAGNNN   CTG--- 3' 3' ---GTC   NNNGAC--- 5'	CaiI
AlwXI		67	Acinetobacter lwoffii X	5' GCAGC 3' CGTCG	5' ---GCAGCN7N   NNNN--- 3' 3' ---CGTCGN7NNNNN   --- 5'	BbvI, BseKI, BseXI, Bsp423I, Bst12I, Bst71I, BstV1I
Ama87I			Alteromonas macleodii 87	5' CYCGRG 3' GRGCYC	5' ---C   YCGRG--- 3' 3' ---GRGCY   C--- 5'	AquI, AvaI,  BmeT110I,  BsiHKCI, BsoBI, Eco88I, Nli3877I, NspSAI
AmaCSI		26714	Arthrospira maxima CS-328	5' GCTCCA 3' CGAGGT	5' ---GCTCCAN8NNN   --- 3' 3' ---CGAGGTN8N   NN--- 5'	None as of 4 May 2018
AocI		74	Anabaena sp.	5' CCTNAGG 3' GGANTCC	5' ---CC   TNAGG--- 3' 3' ---GGANT   CC--- 5'	AyI, Bse21I, Bsu36I, Eco81I, Lmu60I, OaNI, MstII, SauI, SshAI
AocII			Anabaena sp.	5' GDGCHC 3' CHCGDG	5' ---GDGCH   C--- 3' 3' ---C   HCGDG--- 5'	BmyI, BsoCI, Bsp1286I, BspLS2I, MhlI, NspII, SduI
AorI		77	Acetobacter aceti orleanensis	5' CCWGG 3' GGWCC	5' ---CC   WGG--- 3' 3' ---GGW   CC--- 5'	BseBI, BstNI, BstOI, Bst2UI, EcoRII, MvaI, Sth117I, Tai
Aor13HI [44]			Acidiphilium organovorum 13H	5' TCCGGA 3' AGGCCT	5' ---T   CCGGA--- 3' 3' ---AGGCC   T--- 5'	AccIII, BbvAIII, BlfI, BseAI, BsiMI, BspEI, CauB3I, Kpn2I, MroI, PtaI
Aor51HI [45]		76	Acidiphilium organovorum 51H	5' AGCGCT 3' TCGCGA	5' ---AGC   GCT--- 3' 3' ---TCG   CGA--- 5'	AfeI, AitI, Eco47III, FunI
AosI			Anabaena oscillarioides	5' TGCGCA 3' ACGCGT	5' ---TGC   GCA--- 3' 3' ---ACG   CGT--- 5'	Acc16I, AviII, FdiII, FspI, MstI, NsbI, PamI, Pun14627I
AosII			Anabaena oscillarioides	5' GRCGYC 3' CYGCRG	5' ---GR   CGYC--- 3' 3' ---CYGC   RG--- 5'	AcyI, AstWI, BbiII, BsaHI, BstACI, Hin1I, HgiI, HgiGI, Msp17I, PamII
ApaI [11] [30] [46]			Acetobacter pasteurianus pasteurianus	5' GGGCCC 3' CCCGGG	5' ---GGGCC   C--- 3' 3' ---C   CCGGG--- 5'	Bsp120I, PpeI, PspOMI
ApaBI [47]			Acetobacter pasteurianus B	5' GCAN5TGC 3' CGTN5ACG	5' ---GCANNNNN   TGC--- 3' 3' ---CGT   NNNNNACG--- 5'	BstAPI
ApaCI			Acetobacter pasteurianus C	5' GGATCC 3' CCTAGG	5' ---G   GATCC--- 3' 3' ---CCTAG   G--- 5'	AliI, BamHI, BnaI, Bsp4009I, BstI, NspSAIV, Pfl8I, SolI, SurI
ApaLI [48] [49]			Acetobacter pasteurianus	5' GTGCAC 3' CACGTG	5' ---G   TGCAC--- 3' 3' ---CACGT   G--- 5'	Alw44I, SnoI, VneI
ApaORI		86	Acetobacter pasteurianus	5' CCWGG 3' GGWCC	5' ---CC   WGG--- 3' 3' ---GGW   CC--- 5'	AjnI, BstNI, BstOI, Bst1I, Bst2I, Fsp1604I, MvaI, Psp6I, PspGI
ApeKI [50]			Aeropyrum pernix K1	5' GCWGC 3' CGWCG	5' ---G   CWGC--- 3' 3' ---CGWC   G--- 5'	AceI, SuiI, Taq52I, TseI
ApiI		2315	Arthrobacter picolinophilus	5' CTGCAG 3' GACGTC	5' ---CTGCA   G--- 3' 3' ---G   ACGTC--- 5'	Asp713I, Bsp63I, CfrA4I, PaePI, Pfl21I, Psp23I, PstI, SflI, Sst12I
ApoI [51]			Arthrobacter protophormiae	5' RAATTY 3' YTTAAR	5' ---R   AATTY--- 3' 3' ---YTTAA   R--- 5'	AcsI, CfaI,  FsiI, XapI, EcoRI
AplI		25962	Arthrospira platensis NIES-39	5' CTGCAG 3' GACGTC	5' ---CTGCA   G--- 3' 3' ---G   ACGTC--- 5'	See this site for a complete list.
ApyI		93	Arthrobacter pyridinolis	5' CCWGG 3' GGWCC	5' ---CC   WGG--- 3' 3' ---GGW   CC--- 5'	BciBII, BptI, BseBI, BstNI, BstOI, Bst2UI, Bst38I, Bst100I, MvaI
ApyPI		14756	Arcanobacterium pyogenes	5' ATCGAC 3' TAGCTG	5' ---ATCGACN17NNN   --- 3' 3' ---TAGCTGN17N   NN--- 5'	None as of 4 August 2019
AquI			Agmenellum quadruplicatum PR-6	5' CYCGRG 3' GRGCYC	5' ---C   YCGRG--- 3' 3' ---GRGCY   C--- 5'	BcoI,  BmeT110I,  BsmAI, BsoMAI, BsoBI, BstSI, Eco27kI, OfoI
AquII		20238	Agmenellum quadruplicatum PR-6	5' GCCGNAC 3' CGGCNTG	5' ---GCCGNACN17NNN   --- 3' 3' ---CGGCNTGN17N   NN--- 5'	None as of 4 August 2019
AquIII		20239	Agmenellum quadruplicatum PR-6	5' GAGGAG 3' CTCCTC	5' ---GAGGAGN17NNN   --- 3' 3' ---CTCCTCN17N   NN--- 5'	BseRI
AquIV		20240	Agmenellum quadruplicatum PR-6	5' GRGGAAG 3' CYCCTTC	5' ---GRGGAAGN16NNN   --- 3' 3' ---CYCCTTCN16N   NN--- 5'	None as of 4/9/19
ArsI		19405	Arthrobacter sp. NTS	5' GACN6TTYG 3' CTGN6AARC	5' ---NNNNN   NN7GACN6TTYGN5NNNNNN   --- 3' 3' ---   NNNNNNN7CTGN6AARCN5N   NNNNN--- 5'	None as of Oct. 28 2020
AscI [11] [52]			Arthrobacter sp.	5' GGCGCGCC 3' CCGCGCGG	5' ---GG   CGCGCC--- 3' 3' ---CCGCGC   GG--- 5'	PalAI, SgsI
AseI [53]		96	Aquaspirillum serpens	5' ATTAAT 3' TAATTA	5' ---AT   TAAT--- 3' 3' ---TAAT   TA--- 5'	AsnI, BpoAI, PshBI, Sru4DI, VspI
AseII [53]		97	Aquaspirillum serpens	5' CCSGG 3' GGSCC	5' ---CC   SGG--- 3' 3' ---GGS   CC--- 5'	AhaI, AsuC2I, BcnI, CauII, EcoHI, HgiS22I, Kpn49kII, Mgl14481I, NciI
AsiI			Azotobacter sp.	5' GGATCC 3' CCTAGG	5' ---G   GATCC--- 3' 3' ---CCTAG   G--- 5'	ApaCI, BamHI, BnaI, Bsp4009I, BstI, OkrAI, Pfl8I, SurI, Uba4009I
AsiAI		2853	Arthrobacter sp. A7359	5' ACCGGT 3' TGGCCA	5' ---A   CCGGT--- 3' 3' ---TGGCC   A--- 5'	AgeI, AsiGI, BshTI, CsiAI, CspAI, PinAI
AsiGI		10828	Arthrobacter sp. G	5' ACCGGT 3' TGGCCA	5' ---A   CCGGT--- 3' 3' ---TGGCC   A--- 5'	AgeI, AsiAI, BshTI, CsiAI, CspAI, PinAI
AsiSI			Arthrobacter sp.	5' GCGATCGC 3' CGCTAGCG	5' ---GCGAT   CGC--- 3' 3' ---CGC   TAGCG--- 5'	RgaI, SfaAI, , SgfI
Asi256I		18472	Arthrobacter sp. Ck256	5' GATC 3' CTAG	5' ---G   ATC--- 3' 3' ---CTA   G--- 5'	See this site for a complete list.
Asi372I		15803	Arthrobacter sp. Mn372	5' ATGCAT 3' TACGTA	5' ---ATGCA   T--- 3' 3' ---T   ACGTA--- 5'	Ppu10I, EcoT22I, Mph1103I, NsiI, Zsp2I, BfrBI, Csp68KIII, PinBI, SepI, SspD5II
AsnI [54]		98	Arthrobacter sp. N-CM	5' ATTAAT 3' TAATTA	5' ---AT   TAAT--- 3' 3' ---TAAT   TA--- 5'	AseI, BpoAI, PshBI, Sru4DI, VspI
AspI [55]			Achromobacter sp. 699	5' GACNNNGTC 3' CTGNNNCAG	5' ---GACN   NNGTC--- 3' 3' ---CTGNN   NCAG--- 5'	AtsI, PflFI, PsyI, TelI, Tth111I
Asp10HI			Acidiphilium sp. 10H	5' TTCGAA 3' AAGCTT	5' ---TT   CGAA--- 3' 3' ---AAGC   TT--- 5'	AsuII, BspT104I, BstBI, CbiI, Csp68KII, PlaII, PpaAI, Ssp1I
Asp10HII		100	Acidiphilium sp. 10H	5' CCAN5TGG 3' GGTN5ACC	5' ---CCANNNN   NTGG--- 3' 3' ---GGTN   NNNNACC--- 5'	AccB7I, AcpII, BasI, Esp1396I, PflBI, PflMI, Van91I
Asp26HI		111	Acidiphilium sp. 26H	5' GAATGC 3' CTTACG	5' ---GAATGCN   --- 3' 3' ---CTTAC   GN--- 5'	Asp27HI, Asp35HI, Asp36HI, BsaMI, BscCI, BsmI, PctI
Asp27HI		112	Acidiphilium sp. 27H	5' GAATGC 3' CTTACG	5' ---GAATGCN   --- 3' 3' ---CTTAC   GN--- 5'	Asp35HI, Asp36HI, Asp40HI,  BmaHI,  BsaMI, BscCI, BsmI
Asp35HI		117	Acidiphilium sp. 35H	5' GAATGC 3' CTTACG	5' ---GAATGCN   --- 3' 3' ---CTTAC   GN--- 5'	Asp36HI, Asp40HI, Asp50HI, BsaMI, BscCI, BsmI, Mva1269I
Asp36HI		118	Acidiphilium sp. 36H	5' GAATGC 3' CTTACG	5' ---GAATGCN   --- 3' 3' ---CTTAC   GN--- 5'	Asp40HI, Asp50HI,  BmaHI,  BscCI, BsmI, Mva1269I, PctI
Asp40HI		120	Acidiphilium sp. 40H	5' GAATGC 3' CTTACG	5' ---GAATGCN   --- 3' 3' ---CTTAC   GN--- 5'	Asp27HI, Asp36HI, Asp50HI, BsaMI, BscCI, BsmI, Mva1269I
Asp50HI		122	Acidiphilium sp. 50H	5' GAATGC 3' CTTACG	5' ---GAATGCN   --- 3' 3' ---CTTAC   GN--- 5'	Asp26HI, Asp35HI, Asp36HI, BsaMI, BscCI, BsmI, Mva1269I
Asp700I [56]			Achromobacter sp. 700	5' GAAN4TTC 3' CTTN4AAG	5' ---GAANN   NNTTC--- 3' 3' ---CTTNN   NNAAG--- 5'	BbvAI, MroXI, PdmI, XmnI
Asp713I		131	Achromobacter sp. 713	5' CTGCAG 3' GACGTC	5' ---CTGCA   G--- 3' 3' ---G   ACGTC--- 5'	AjoI, AliAJI, BloHII, CfrA4I, Ecl37kI, MhaAI, PstI, SflI, Srl5DI, YenI
Asp718I [57]			Achromobacter sp. 718	5' GGTACC 3' CCATGG	5' ---G   GTACC--- 3' 3' ---CCATG   G--- 5'	Acc65I, AhaB8I, KpnI, SthI
Asp745I			Achromobacter sp. 745	5' GGWCC 3' CCWGG	5' ---G   GWCC--- 3' 3' ---CCWG   G--- 5'	Bme18I, BsrAI, CauI, Eco47I, ErpI, FdiI, SinI, VpaK11AI, VpaK11BI
AspAI			Alcaligenes sp.	5' GGTNACC 3' CCANTGG	5' ---G   GTNACC--- 3' 3' ---CCANTG   G--- 5'	AcrII, Bse64I, BseT10I, BstEII, BstPI, Eco91I, EcoO65I, PspEI
AspA2I		6959	Arthrobacter sp. A2	5' CCTAGG 3' GGATCC	5' ---C   CTAGG--- 3' 3' ---GGATC   C--- 5'	AvrBII, AvrII, BlnI, BspA2I, XmaJI
AspEI [58]			Aureobacterium sp.	5' GACN5GTC 3' CTGN5CAG	5' ---GACNNN   NNGTC--- 3' 3' ---CTGNN   NNNCAG--- 5'	AhdI,  BmeRI,  BspOVI, DriI, Eam1105I, EclHKI, NruGI
AspHI [59]			Achromobacter sp. H	5' GWGCWC 3' CWCGWG	5' ---GWGCW   C--- 3' 3' ---C   WCGWG--- 5'	Alw21I, Bbv12I, Bsh45I, BsiHKAI,  Bsm6I,  HgiAI, MspV281I
AspLEI			Arthrobacter sp. LE3860	5' GCGC 3' CGCG	5' ---GCG   C--- 3' 3' ---C   GCG--- 5'	BspLAI, BstHHI, CfoI, FnuDIII, HhaI, Hin6I, HinP1I, HsoI, HspAI, SciNI
AspMI		2977	Acinetobacter sp. M	5' AGGCCT 3' TCCGGA	5' ---AGG   CCT--- 3' 3' ---TCC   GGA--- 5'	AatI, Eco147I, GdiI, PceI, SarI, Sru30DI, SseBI, SteI, StuI
AspMDI			Alcaligenes sp. MD1	5' GATC 3' CTAG	5' ---   GATC--- 3' 3' ---CTAG   --- 5'	BfuCI, Bsp143I, BstMBI, DpnII, Kzo9I, MboI, NdeII, Sau3AI
AspNI			Anabaena sp. J3	5' GGNNCC 3' CCNNGG	5' ---GGN   NCC--- 3' 3' ---CCN   NGG--- 5'	BmiI,  BscBI, BspLI, NlaIV, PspN4I
AspS9I			Arthrobacter sp. S9	5' GGNCC 3' CCNGG	5' ---G   GNCC--- 3' 3' ---CCNG   G--- 5'	AsuI, AvcI, Bac36I, Bal228I, FmuI, NspIV, PspPI, Sau96I
AssI		4930	Arthrobacter sp.	5' AGTACT 3' TCATGA	5' ---AGT   ACT--- 3' 3' ---TCA   TGA--- 5'	Acc113I,  BmcAI, Bpa34I,  DpaI, Eco255I, RflFII, ScaI, ZrmI
AstWI			Anabaena sp.	5' GRCGYC 3' CYGCRG	5' ---GR   CGYC--- 3' 3' ---CYGC   RG--- 5'	AcyI, AsuIII, BsaHI, BstACI, Hin1I, HgiI, HgiDI, HgiGI, Msp17I
AsuI [60]			Anabaena subcylindrica	5' GGNCC 3' CCNGG	5' ---G   GNCC--- 3' 3' ---CCNG   G--- 5'	AspS9I, AvcI, CcuI, Cfr13I, FmuI, MaeK81II, Nsp7121I, PspPI, UnbI
AsuII [61]			Anabaena subcylindrica	5' TTCGAA 3' AAGCTT	5' ---TT   CGAA--- 3' 3' ---AAGC   TT--- 5'	AcpI, Bpu14I, Bsp119I, BspT104I, Csp45I, FspII, LspI, NspV, SfuI
AsuIII			Anabaena subcylindrica	5' GRCGYC 3' CYGCRG	5' ---GR   CGYC--- 3' 3' ---CYGC   RG--- 5'	AcyI, AsuIII, BbiII, BsaHI, BstACI, Hin1I, HgiHII, Hsp92I, Msp17I
AsuC2I		2901	Actinobacillus suis C2	5' CCSGG 3' GGSCC	5' ---CC   SGG--- 3' 3' ---GGS   CC--- 5'	AhaI, AseII, BcnI, Eco1831I, EcoHI, Kpn49kII, Mgl14481I, NciI
AsuHPI [62]		2811	Actinobacillus suis HP	5' GGTGA 3' CCACT	5' ---GGTGAN6NN   --- 3' 3' ---CCACTN6N   N--- 5'	HphI, SspD5I
AsuNHI [62]			Actinobacillus suis NH	5' GCTAGC 3' CGATCG	5' ---G   CTAGC--- 3' 3' ---CGATC   G--- 5'	AceII, BmtI,  BspOI,  LlaG2I, NheI, PstNHI
AtsI			Aureobacterium testaceum 4842	5' GACNNNGTC 3' CTGNNNCAG	5' ---GACN   NNGTC--- 3' 3' ---CTGNN   NCAG--- 5'	AspI, PflFI, PsyI, TelI, Tth111I
AvaI [14] [63] [64]			Anabaena variabilis	5' CYCGRG 3' GRGCYC	5' ---C   YCGRG--- 3' 3' ---GRGCY   C--- 5'	AquI, Ama87I, BsiHKCI, BsoBI, BspLU4I, Eco88I, NspIII, PlaAI
AvaII [12] [14] [41] [63] [64]			Anabaena variabilis	5' GGWCC 3' CCWGG	5' ---G   GWCC--- 3' 3' ---CCWG   G--- 5'	Bme18I, Bme216I, BsrAI, Eco47I, Kzo49I, Psp03I, SmuEI, VpaK11AI
AvcI			Actinomyces violaceoniger cristalomycini	5' GGNCC 3' CCNGG	5' ---G   GNCC--- 3' 3' ---CCNG   G--- 5'	AspS9I, BshKI, BsiZI, Bsp1894I, BspBII, BspF4I, Bsu54I, Pde12I
AviII			Anabaena variabillis (halle)	5' TGCGCA 3' ACGCGT	5' ---TGC   GCA--- 3' 3' ---ACG   CGT--- 5'	Acc16I, AosI, FdiII, FspI, MstI, NsbI, PamI, Pun14627I
AvrII [11] [29]		173	Anabaena variabilis UW	5' CCTAGG 3' GGATCC	5' ---C   CTAGG--- 3' 3' ---GGATC   C--- 5'	AspA2I, AvrBII, BlnI, BspA2I, XmaJI
AvrBII		171	Arthrobacter variabilis	5' CCTAGG 3' GGATCC	5' ---C   CTAGG--- 3' 3' ---GGATC   C--- 5'	AspA2I, AvrII, BlnI, BspA2I, XmaJI
AxyI [65]		174	Acetobacter xylinus	5' CCTNAGG 3' GGANTCC	5' ---CC   TNAGG--- 3' 3' ---GGANT   CC--- 5'	AocI, BliHKI, Bse21I, BspR7I, Bsu36I, CvnI, Eco81I, Lmu60I

§ An HF version of this enzyme is available

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Notes

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