Provincial Trunk Highway 1 is Manitoba's section of the Trans-Canada Highway. It is a heavily used, 4-lane divided highway, with the exception of a short 18 km section in the southeastern corner of the province. It is the main link between southern Manitoba's largest cities, and also serves as the province's main transportation link to the neighbouring provinces of Saskatchewan and Ontario. The highway is the only major east-west divided highway in Manitoba, and carries a large majority of east-west traffic within and through the province. It has full freeway status sections at Portage la Prairie and Winnipeg. The total distance of the Trans-Canada Highway in Manitoba is approximately 490 km (300 mi).
Provincial Trunk Highway 6 is a provincial primary highway located in the Canadian province of Manitoba. It runs from the Perimeter Highway of Winnipeg to the Thompson south city limits. It is also the main highway connecting Winnipeg to northern Manitoba. The speed limit is 100 km/h. The route is also used to deliver nickel from the Thompson mine to the Royal Canadian Mint in Winnipeg. The section of highway between its southern terminus near Winnipeg and the second junction with PTH 68 near Eriksdale is part of the Northern Woods and Water Route. The portion of the highway between Ponton and Thompson was known as Highway 391 prior to 1986.
Provincial Trunk Highway 8 is a provincial primary highway located in the Canadian province of Manitoba. It runs from the north limit of the City of Winnipeg, where it meets with Route 180, north to Hecla-Grindstone Provincial Park. The highway between Winnipeg and PR 230 is known as McPhillips Street. At PR 230, McPhillips Street becomes McPhillips Road and continues along PR 230 to PTH 9. The route is a major road connecting Winnipeg with the communities of Winnipeg Beach and Gimli. The speed limit is 100 km/h (60 mph).
Provincial Trunk Highway 27 is a very short provincial highway in the Canadian province of Manitoba. It runs from PTH 8 to PTH 9.
Provincial Trunk Highway 60 is a provincial highway in the Canadian province of Manitoba. It runs from PTH 10 to PTH 6. Much of its length runs adjacent to the north shore of Lake Winnipegosis.
Provincial Trunk Highway 89 is a provincial highway in the Canadian province of Manitoba. The entire road lies within the Rural Municipality of Piney and is 10 kilometres long. It runs from PTH 12 south to Piney and the U.S. border. South of the border it becomes Minnesota State Highway 89.
Provincial Trunk Highway 3A is a provincial primary highway located in the Canadian province of Manitoba. It runs from PTH 3 to the same route concurrent with PTH 34. The highway continues as PR 423 from its eastern terminus.
Provincial Trunk Highway 3 (PTH 3) is a major provincial highway located in the Canadian province of Manitoba. It runs from the Saskatchewan boundary to the southwest city limits of Winnipeg, where it continues as Winnipeg Route 155. Prior before to the implementation of Winnipeg's City Route System, it extended to Pembina Highway.
Provincial Trunk Highway 39 is a provincial highway in the Canadian province of Manitoba. It runs from PTH 6 to PTH 10.
Provincial Trunk Highway 30 is a provincial highway in the Canadian province of Manitoba. It runs from the Neche–Gretna Border Crossing at the Canada–United States border to PTH 14.
Provincial Trunk Highway 32 is a provincial primary highway located in the Canadian province of Manitoba. It runs from PTH 14 at Winkler to the U.S. border, where it becomes North Dakota State Highway 32. Between its northern end and its intersection with PR 243, PTH 32 follows the Boundary Commission Trail.
Provincial Trunk Highway 52 is a provincial highway in the Canadian province of Manitoba. It runs east from PTH 59, through the city of Steinbach, to La Broquerie where it ends at its junction with PR 210 and PR 302. It is a two-lane highway, except from Mitchell to the eastern edge of Steinbach, where it is a divided, four-lane road.
Provincial Trunk Highway 10 is a provincial primary highway located in the Canadian province of Manitoba.
Provincial Trunk Highway 44 is an east-west provincial highway in the Eastman Region of the Canadian province of Manitoba.
Provincial Trunk Highway 22 is a short north-south provincial highway in the Canadian province of Manitoba. It runs from PTH 23 near Elgin to PTH 2 and PR 250 in Souris. This highway is the main access road to the renowned Souris Swinging Bridge.
Provincial Trunk Highway 25 is a provincial highway in the Canadian province of Manitoba. It is a short east-west route starting at PR 259 at Wheatland, east through Rivers, and terminating at PTH 10 six kilometres (3.7 mi) north of Forrest. PTH 25 serves as the major route, via PTH 10, between Rivers and Brandon.
Provincial Trunk Highway 83 is a 402 kilometres (250 mi) long, major north-south highway that runs in the far western region of the Canadian province of Manitoba. It travels from the North Dakota border south of Melita, north through Virden, Birtle, Russell, and Roblin to its northern terminus with PTH 10 in the town of Swan River. Along with US 83, PTH 83 is part of a continuously numbered north-south highway in North America with a combined distance of 3,450 kilometres (2,140 mi).
Provincial Trunk Highway 50 is a provincial highway in the south-central region of the Canadian province of Manitoba. It runs from PTH 16 to PTH 5 and PR 361 in the village of McCreary.
Provincial Trunk Highway 41 is a short provincial highway in the far southwest region of the Canadian province of Manitoba. It runs from PTH 1 and PR 542 in the village of Kirkella to PTH 16 and PTH 83 just south of Binscarth.
Provincial Trunk Highway 34 is a provincial primary highway located in the Canadian province of Manitoba. It runs from the U.S. border to PTH 16 at the town of Gladstone.
Hwy 48 at Manitoba – Saskatchewan border near Kola 
PR 542 in Kola 
PR 256 near Cromer 
PTH 83 in Virden
PTH 1 (TCH) near Virden 
