Provincial Trunk Highway 1 is Manitoba's section of the Trans-Canada Highway. It is a heavily used, 4-lane divided highway, with the exception of a short 18 km section in the southeastern corner of the province. It is the main link between southern Manitoba's largest cities, and also serves as the province's main transportation link to the neighbouring provinces of Saskatchewan and Ontario. The highway is the only major east-west divided highway in Manitoba, and carries a large majority of east-west traffic within and through the province. It has full freeway status sections at Portage la Prairie and Winnipeg. The total distance of the Trans-Canada Highway in Manitoba is approximately 490 km (300 mi).
Provincial Trunk Highway 4 is a provincial highway in the Canadian province of Manitoba. The highway connects the city of Selkirk to PTH 59, the main route to Grand Beach and cottage country on the east side of Lake Winnipeg.
Provincial Trunk Highway 6 is a provincial primary highway located in the Canadian province of Manitoba. It runs from the Perimeter Highway of Winnipeg to the Thompson south city limits. It is also the main highway connecting Winnipeg to northern Manitoba. The speed limit is 100 km/h. The route is also used to deliver nickel from the Thompson mine to the Royal Canadian Mint in Winnipeg. The section of highway between its southern terminus near Winnipeg and the second junction with PTH 68 near Eriksdale is part of the Northern Woods and Water Route. The portion of the highway between Ponton and Thompson was known as Highway 391 prior to 1986.
Provincial Trunk Highway 8 is a provincial primary highway located in the Canadian province of Manitoba. It runs from the north limit of the City of Winnipeg, where it meets with Route 180, north to Hecla-Grindstone Provincial Park. The highway between Winnipeg and PR 230 is known as McPhillips Street. At PR 230, McPhillips Street becomes McPhillips Road and continues along PR 230 to PTH 9. The route is a major road connecting Winnipeg with the communities of Winnipeg Beach and Gimli. The speed limit is 100 km/h (60 mph).
Provincial Trunk Highway 2 is a 315-kilometre (196-mile) highway in the Canadian province of Manitoba. It runs from Highway 13 at the Manitoba-Saskatchewan border to Winnipeg's Perimeter Highway near Oak Bluff.
Provincial Trunk Highway 60 is a provincial highway in the Canadian province of Manitoba. It runs from PTH 10 to PTH 6. Much of its length runs adjacent to the north shore of Lake Winnipegosis.
Provincial Trunk Highway 3 (PTH 3) is a major provincial highway located in the Canadian province of Manitoba. It runs from the Saskatchewan boundary to the southwest city limits of Winnipeg, where it continues as Winnipeg Route 155. Prior before to the implementation of Winnipeg's City Route System, it extended to Pembina Highway.
Provincial Trunk Highway 77 is a provincial highway in the Canadian province of Manitoba. It runs from the Saskatchewan boundary near Westgate to PTH 10 near Baden. It was designated in 1987, replacing PR 277.
Provincial Trunk Highway 5 is a provincial primary highway located in the Canadian province of Manitoba.
The Northern Woods and Water Route is a 2,400-kilometre (1,500 mi) route through northern British Columbia, Alberta, Saskatchewan and Manitoba in Western Canada. As early as the 1950s, community groups came together to establish a northern travel route; this was proposed as the Northern Yellowhead Transportation Route. The Northern Woods and Water Route Association was established in 1974, and encouraged promotion of the route with the promise of an increase in tourist travel. The route was designated in 1974 and is well signed throughout its component highways. The route starts at Dawson Creek as the Spirit River Highway and ends at the Perimeter of Winnipeg, Manitoba, after running through the northern regions of the western provinces. From west to east, the Northern Woods and Water Route (NWWR) incorporates portions of British Columbia Highway 49; Alberta Highways 49, 2A, 2, & 55; Saskatchewan Highways 55 & 9; Manitoba Provincial Road 283 and Trunk Highways 10, 5, 68 & 6. The halfway point of the NWWR is approximately at Goodsoil, Saskatchewan.
Provincial Trunk Highway 10 is a provincial primary highway located in the Canadian province of Manitoba.
Provincial Trunk Highway 44 is an east-west provincial highway in the Eastman Region of the Canadian province of Manitoba.
Provincial Road 268, known locally as the Lenswood Highway, is a 44.7-kilometre-long (27.8 mi) north-south provincial road in the Swan River Valley of the Parkland Region of Manitoba. It serves the town of Birch River and the hamlet of Lenswood, while also acting as a shortcut for travelers along PTH 10 wishing to bypass the town of Swan River.
Provincial Road 266, is a short 24.0-kilometre-long (14.9 mi) north-south provincial road in the Swan River Valley of the Parkland Region of Manitoba. It serves as a connection between the town of Bowsman and Birch River as well as a longer alternative to PTH 10 between the same two communities.
Provincial Trunk Highway 24 is a provincial highway in the Canadian province of Manitoba. It is an east–west route that runs from PTH 83 near Miniota, east through Oak River and Rapid City to the junction of PTH 10 and PR 262 between Brandon and Minnedosa.
Provincial Trunk Highway 25 is a provincial highway in the Canadian province of Manitoba. It is a short east-west route starting at PR 259 at Wheatland, east through Rivers, and terminating at PTH 10 six kilometres (3.7 mi) north of Forrest. PTH 25 serves as the major route, via PTH 10, between Rivers and Brandon.
Provincial Trunk Highway 50 is a provincial highway in the south-central region of the Canadian province of Manitoba. It runs from PTH 16 to PTH 5 and PR 361 in the village of McCreary.
Provincial Trunk Highway 41 is a short provincial highway in the far southwest region of the Canadian province of Manitoba. It runs from PTH 1 and PR 542 in the village of Kirkella to PTH 16 and PTH 83 just south of Binscarth.
Provincial Trunk Highway 20 is a provincial highway in the Canadian province of Manitoba. It runs from PTH 5 and PR 582 just south of Ochre River to PTH 10 in the village of Cowan. The highway provides an eastern alternative access option to Dauphin along with PTH 20A.
Provincial Road 243 is an east-west provincial road in the Pembina Valley Region of the Canadian province of Manitoba. It runs from PTH 75 near Emerson to PTH 32 near Friedensfeld West. Along the route, it passes north of Gretna using a small concurrence with PTH 30.
Highway 9 at Saskatchewan boundary
PTH 10 in The Pas 
