Metabolic typing is a pseudoscience whose proponents believe that each person has a unique metabolism, and that the proportion of macromolecules (proteins, carbohydrates and fats) which are optimal for one person may not be for a second, and could even be detrimental to them.
Metabolic typing uses common visible symptoms related to the skin, eyes, and other parts of the body to assess different aspects of a person's metabolism and categorize them into broad metabolic types. In addition, some proponents of metabolic typing use tests such as hair analysis to determine a person's metabolic type. [1]
A number of somewhat different metabolic typing diet plans are currently marketed, though the validity and effectiveness of metabolic typing have yet to be established. [2]
Metabolic typing was introduced by William Donald Kelley, a dentist, in the 1960s. Kelley advocated basing dietary choices on the activity of one's sympathetic and parasympathetic nervous systems. In 1970, Kelley was convicted of practicing medicine without a license, as he had diagnosed a patient with lung cancer based on a fingerstick blood test and prescribed nutritional therapy. He continued to promote a metabolic typing diet through the 1980s. [3] The practice has been further developed by others including Harold J. Kristal and William Wolcott.
Some metabolic typing companies[ which? ] use a battery of blood and urine tests performed by reputable laboratories, but interpret the results in an unconventional and medically questionable fashion. [2] During a 1985 investigation into one such firm, an investigator sent two separate samples of his own blood and urine for analysis. He received two drastically different "metabolic typing" reports and dietary plans. Both plans involved the purchase of dietary supplements costing several dollars per day. [2]
"Metabolic therapy", including administration of laetrile, was promoted for cancer patients by John Richardson in the San Francisco Bay Area in the 1970s, until his arrest for violating the California Cancer Law and revocation of his license by the California Board of Medical Quality Assurance. [4]
The Memorial Sloan-Kettering Cancer Center (MSKCC) website describes metabolic therapies as "strict dietary and detoxification regimens touted to prevent and treat cancer and degenerative diseases", a term and definition different from that used for metabolic typing in this Wikipedia article. The MSKCC website notes, in relation to three such anti-cancer therapies, that "...retrospective reviews of the Gerson, Kelley, and Contreras metabolic therapies show no evidence of efficacy." [5]
William Donald Kelley, in his book [ citation needed ], classified the Metabolism of an individual into three categories. Few are fast oxidizer, few are a slow oxidizer. Some have a normal rate of food oxidization called mixed oxidizer. Based on this rate of oxidization the Diet (nutrition) for an individual varies. Since fast oxidizers oxidize food quickly, they are advised to rely more on fat protein efficient diet. This diet will help them to bear hunger. Meanwhile, slow oxidizers are given carbohydrate efficient diet. Eating more proteins or fats can cause Abdominal pain in them. Mixed oxidizer eat a mixture of fat and protein efficient diet. [6]
A carbohydrate is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 and thus with the empirical formula Cm(H2O)n, which does not mean the H has covalent bonds with O. However, not all carbohydrates conform to this precise stoichiometric definition, nor are all chemicals that do conform to this definition automatically classified as carbohydrates.
In nutrition, biology, and chemistry, fat usually means any ester of fatty acids, or a mixture of such compounds, most commonly those that occur in living beings or in food.
The following is a glossary of diabetes which explains terms connected with diabetes.
Ketone bodies are water-soluble molecules or compounds that contain the ketone groups produced from fatty acids by the liver (ketogenesis). Ketone bodies are readily transported into tissues outside the liver, where they are converted into acetyl-CoA – which then enters the citric acid cycle and is oxidized for energy. These liver-derived ketone groups include acetoacetic acid (acetoacetate), beta-hydroxybutyrate, and acetone, a spontaneous breakdown product of acetoacetate.
Isoleucine (symbol Ile or I) is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+3 form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO− form under biological conditions), and a hydrocarbon side chain with a branch (a central carbon atom bound to three other carbon atoms). It is classified as a non-polar, uncharged (at physiological pH), branched-chain, aliphatic amino acid. It is essential in humans, meaning the body cannot synthesize it. Essential amino acids are necessary in the human diet. In plants isoleucine can be synthesized from threonine and methionine. In plants and bacteria, isoleucine is synthesized from a pyruvate employing leucine biosynthesis enzymes. It is encoded by the codons AUU, AUC, and AUA.
Ketosis is a metabolic state characterized by elevated levels of ketone bodies in the blood or urine. Physiological ketosis is a normal response to low glucose availability. In physiological ketosis, ketones in the blood are elevated above baseline levels, but the body's acid–base homeostasis is maintained. This contrasts with ketoacidosis, an uncontrolled production of ketones that occurs in pathologic states and causes a metabolic acidosis, which is a medical emergency. Ketoacidosis is most commonly the result of complete insulin deficiency in type 1 diabetes or late-stage type 2 diabetes. Ketone levels can be measured in blood, urine or breath and are generally between 0.5 and 3.0 millimolar (mM) in physiological ketosis, while ketoacidosis may cause blood concentrations greater than 10 mM.
Food energy is chemical energy that animals derive from their food to sustain their metabolism, including their muscular activity.
Low-carbohydrate diets restrict carbohydrate consumption relative to the average diet. Foods high in carbohydrates are limited, and replaced with foods containing a higher percentage of fat and protein, as well as low carbohydrate foods.
Inborn errors of metabolism form a large class of genetic diseases involving congenital disorders of enzyme activities. The majority are due to defects of single genes that code for enzymes that facilitate conversion of various substances (substrates) into others (products). In most of the disorders, problems arise due to accumulation of substances which are toxic or interfere with normal function, or due to the effects of reduced ability to synthesize essential compounds. Inborn errors of metabolism are often referred to as congenital metabolic diseases or inherited metabolic disorders. Another term used to describe these disorders is "enzymopathies". This term was created following the study of biodynamic enzymology, a science based on the study of the enzymes and their products. Finally, inborn errors of metabolism were studied for the first time by British physician Archibald Garrod (1857–1936), in 1908. He is known for work that prefigured the "one gene–one enzyme" hypothesis, based on his studies on the nature and inheritance of alkaptonuria. His seminal text, Inborn Errors of Metabolism, was published in 1923.
Max Gerson was a German-born American physician who developed the Gerson therapy, a dietary-based alternative cancer treatment that he claimed could cure cancer and most chronic, degenerative diseases. Gerson therapy involves a plant-based diet with coffee enemas, ozone enemas, dietary supplements and raw calf liver extract, the latter was discontinued in the 1980s after patients were hospitalized for bacterial infections.
A healthy diet is a diet that maintains or improves overall health. A healthy diet provides the body with essential nutrition: fluid, macronutrients such as protein, micronutrients such as vitamins, and adequate fibre and food energy.
Ketonuria is a medical condition in which ketone bodies are present in the urine.
William Donald Kelley was an American orthodontist who developed "non-specific metabolic therapy," an alternative cancer treatment, now known to be ineffective, which he based on his personal belief that "wrong foods [cause] malignancy to grow, while proper foods [allow] natural body defenses to work."
Isomaltulose is a disaccharide carbohydrate composed of glucose and fructose. It is naturally present in honey and sugarcane extracts and is also produced industrially from table sugar (sucrose) and used as a sugar alternative.
Sports nutrition is the study and practice of nutrition and diet with regards to improving anyone's athletic performance. Nutrition is an important part of many sports training regimens, being popular in strength sports and endurance sports. Sports nutrition focuses its studies on the type, as well as the quantity of fluids and food taken by an athlete. In addition, it deals with the consumption of nutrients such as vitamins, minerals, supplements and organic substances that include carbohydrates, proteins and fats.
A diabetic diet is a diet that is used by people with diabetes mellitus or high blood sugar to minimize symptoms and dangerous complications of long-term elevations in blood sugar.
A protein-sparing modified fast or PSMF diet is a type of a very-low-calorie diet with a high proportion of protein calories and simultaneous restriction of carbohydrate and fat. It includes a protein component, fluids, and vitamin and mineral supplementation.
A bland diet is a diet consisting of foods that are generally soft, low in dietary fiber, cooked rather than raw, and not spicy. It is an eating plan that emphasizes foods that are easy to digest. It is commonly recommended for people recovering from surgery, diarrhea, gastroenteritis, or other conditions affecting the gastrointestinal tract. Such a diet is called bland because it is soothing to the digestive tract; it minimizes irritation of tissues. It can also be bland in the sense of "lacking flavor", but it does not always have to be so; nonirritating food can be appetizing food, depending on preparation and individual preferences.
The Oasis of Hope Hospital is a clinic in Tijuana, Mexico providing alternative cancer treatments to its customers. The clinic was founded by the physician Ernesto Contreras. After his death in 2003, the management of the hospital was taken over by his son, Francisco Contreras, and nephew, Daniel Kennedy.