 | This article needs additional citations for verification .(April 2009) |
| Necrobiosis | |
|---|---|
| Specialty | Pathology |
Necrobiosis is the physiological death of a cell, and can be caused by conditions such as basophilia, erythema, or a tumor. It is identified both with [1] and without necrosis.
Necrobiotic disorders are characterized by presence of necrobiotic granuloma on histopathology. Necrobiotic granuloma is described as aggregation of histiocytes around a central area of altered collagen and elastic fibers. Such a granuloma is typically arranged in a palisaded pattern. [2]
It is associated with necrobiosis lipoidica and granuloma annulare.
Necrobiosis differs from apoptosis, which kills a damaged cell to protect the body from harm.
