Keratosis

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Keratosis
Keratosis pilaris arm.jpg
Upper arm showing keratosis pilaris
Specialty Dermatology, medical genetics   OOjs UI icon edit-ltr-progressive.svg

Keratosis (from kerat- + -osis ) [1] is a growth of keratin on the skin or on mucous membranes stemming from keratinocytes, the prominent cell type in the epidermis. More specifically, it can refer to:

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Keratosis pilaris Skin condition characterized by small bumps caused by overproduction of keratin

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Actinic cheilitis Medical condition

Actinic cheilitis is cheilitis caused by long term sunlight exposure. Essentially it is a burn, and a variant of actinic keratosis which occurs on the lip. It is a premalignant condition, as it can develop into squamous cell carcinoma.

An arsenical keratosis is a growth of keratin on the skin caused by arsenic, which occurs naturally in the earth's crust and is widely distributed in the environment, Arsenical compounds are used in industrial, agricultural, and medicinal substances. Arsenic is also found to be an environmental contaminant in drinking water and an occupational hazard for miners and glass workers. Arsenic may also causes other conditions including: Bowen's disease, cardiovascular diseases, developmental abnormalities, neurologic and neurobehavioral disorders, diabetes, hearing loss, hematologic disorders, and various types of cancer. Arsenical keratoses may persist indefinitely, and some may develop into invasive squamous cell carcinoma. Metastatic arsenic squamous cell carcinoma and arsenic-induced malignancies in internal organs such as the bladder, kidney, skin, liver, and colon, may result in death.

A Reactional keratosis is a premalignant keratotic skin lesion that may arise in a variety of long-standing, nonscarring, inflammatory processes such as cutaneous lupus erythematosus for example.

References

  1. Merriam-Webster, Merriam-Webster's Unabridged Dictionary, Merriam-Webster.