Painful bruising syndrome

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Painful bruising syndrome
Other namesAutoerythrocyte sensitization, Gardner–Diamond syndrome, and psychogenic purpura.
Specialty Dermatology

Painful bruising syndrome, also known as autoerythrocyte sensitization, Gardner–Diamond syndrome, and psychogenic purpura, is an idiopathic trauma-induced condition seen in young to middle-aged women who sometimes manifest personality disorders. [1] :829 It is characterized by a distinctive localized purpuric reaction occurring primarily on the legs, face and trunk, with recurring painful ecchymoses variably accompanied by syncope, nausea, vomiting, gastrointestinal and intracranial bleeding. [2] Patients with this condition can experience frequent painful bruising around joints and muscles. Because of the rarity of the disorder, there are few methods of support in place for patients. [3]

Contents

Many patients are labelled with the stigma of having a psychological condition without this having a specifically proven link. There have been cases of painful bruising syndrome reported where there are no additional psychological disorders. This has been known to be put into remission with chemotherapy. It was characterized in 1955 by Frank Gardner and Louis Diamond. [4] [5]

See also

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References

  1. James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN   978-0-7216-2921-6.
  2. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN   978-1-4160-2999-1.
  3. Ivanov, OL; Lvov, AN; Michenko, AV; Künzel, J; Mayser, P; Gieler, U (2009). "Autoerythrocyte sensitization syndrome (Gardner-Diamond syndrome): review of the literature**". Journal of the European Academy of Dermatology and Venereology. 23 (5): 499–504. doi: 10.1111/j.1468-3083.2009.03096.x . ISSN   0926-9959. PMID   19192020. S2CID   27542376.
  4. synd/3229 at Who Named It?
  5. GARDNER FH, DIAMOND LK (July 1955). "Autoerythrocyte sensitization; a form of purpura producing painful bruising following autosensitization to red blood cells in certain women". Blood. 10 (7): 675–90. doi: 10.1182/blood.V10.7.675.675 . PMID   14389381.

Further reading