rubber cis-polyprenylcistransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.5.1.20 | ||||||||
CAS no. | 62213-41-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a rubber cis-polyprenylcistransferase (EC 2.5.1.20) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are poly-cis-polyprenyl diphosphate and isopentenyl diphosphate, whereas its two products are diphosphate and poly-cis-polyprenyl diphosphate longer by one C5 unit.
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is poly-cis-polyprenyl-diphosphate:isopentenyl-diphosphate polyprenylcistransferase. Other names in common use include rubber allyltransferase, rubber transferase, isopentenyl pyrophosphate cis-1,4-polyisoprenyl transferase, cis-prenyl transferase, rubber polymerase, and rubber prenyltransferase. This enzyme participates in biosynthesis of steroids.
Isoprene, or 2-methyl-1,3-butadiene, is a common volatile organic compound with the formula CH2=C(CH3)−CH=CH2. In its pure form it is a colorless volatile liquid. It is produced by many plants and animals (including humans) and its polymers are the main component of natural rubber. C. G. Williams named the compound in 1860 after obtaining it from the pyrolysis of natural rubber; he correctly deduced the empirical formula C5H8.
Farnesyl pyrophosphate (FPP), also known as farnesyl diphosphate (FDP), is an intermediate in the biosynthesis of terpenes and terpenoids such as sterols and carotenoids. It is also used in the synthesis of CoQ, as well as dehydrodolichol diphosphate.
Isopentenyl pyrophosphate isomerase, also known as Isopentenyl-diphosphate delta isomerase, is an isomerase that catalyzes the conversion of the relatively un-reactive isopentenyl pyrophosphate (IPP) to the more-reactive electrophile dimethylallyl pyrophosphate (DMAPP). This isomerization is a key step in the biosynthesis of isoprenoids through the mevalonate pathway and the MEP pathway.
In enzymology, a 4-hydroxybenzoate polyprenyltransferase is an enzyme that catalyzes the chemical reaction
Diphosphomevalonate decarboxylase (EC 4.1.1.33), most commonly referred to in scientific literature as mevalonate diphosphate decarboxylase, is an enzyme that catalyzes the chemical reaction
In enzymology, a 1-deoxy-d-xylulose-5-phosphate synthase (EC 2.2.1.7) is an enzyme in the non-mevalonate pathway that catalyzes the chemical reaction
In enzymology, an adenylate dimethylallyltransferase (EC 2.5.1.27) is an enzyme that catalyzes the chemical reaction
In enzymology, a dimethylallylcistransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a di-trans,poly-cis-decaprenylcistransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a farnesyltranstransferase is an enzyme that catalyzes the chemical reaction.
In enzymology, a geranyltranstransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a heptaprenyl diphosphate synthase is an enzyme that catalyzes the chemical reaction
In enzymology, an anthranilate phosphoribosyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a glucose-1-phosphate thymidylyltransferase is an enzyme that catalyzes the chemical reaction
TRNA dimethylallyltransferase is an enzyme with systematic name dimethylallyl-diphosphate: tRNA dimethylallyltransferase. This enzyme catalyses the following chemical reaction
Trans,polycis-decaprenyl diphosphate synthase is an enzyme with systematic name (2Z,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesylcistransferase . This enzyme catalyses the following chemical reaction
Ditrans,polycis-polyprenyl diphosphate synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase . This enzyme catalyses the following chemical reaction
Trans,polycis-polyprenyl diphosphate synthase is an enzyme with systematic name (2Z,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase . This enzyme catalyses the following chemical reaction
Tritrans,polycis-undecaprenyl-diphosphate synthase is an enzyme with systematic name geranylgeranyl-diphosphate:isopentenyl-diphosphate cistransferase . This enzyme catalyses the following chemical reaction
(2Z,6Z)-farnesyl diphosphate synthase is an enzyme with systematic name dimethylallyl-diphosphate:isopentenyl-diphosphate cistransferase . This enzyme catalyses the following chemical reaction