See also
- Instrumentation
- Instrumentalism, a philosophic theory
- List of collectibles
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The dictionary definition of -tron at Wiktionary, a suffix to denote a complex scientific instrument, like in cyclotron, phytotron, synchrotron, ...
A scientific instrument is a device or tool used for scientific purposes, including the study of both natural phenomena and theoretical research. [1]
Historically, the definition of a scientific instrument has varied, based on usage, laws, and historical time period. [1] [2] [3] Before the mid-nineteenth century such tools were referred to as "natural philosophical" or "philosophical" apparatus and instruments, and older tools from antiquity to the Middle Ages (such as the astrolabe and pendulum clock) defy a more modern definition of "a tool developed to investigate nature qualitatively or quantitatively." [1] [3] Scientific instruments were made by instrument makers living near a center of learning or research, such as a university or research laboratory. Instrument makers designed, constructed, and refined instruments for purposes, but if demand was sufficient, an instrument would go into production as a commercial product. [4] [5]
In a description of the use of the eudiometer by Jan Ingenhousz to show photosynthesis, a biographer observed, "The history of the use and evolution of this instrument helps to show that science is not just a theoretical endeavor but equally an activity grounded on an instrumental basis, which is a cocktail of instruments and techniques wrapped in a social setting within a community of practitioners. The eudiometer has been shown to be one of the elements in this mix that kept a whole community of researchers together, even while they were at odds about the significance and the proper use of the thing." [6]
By World War II, the demand for improved analyses of wartime products such as medicines, fuels, and weaponized agents pushed instrumentation to new heights. [7] Today, changes to instruments used in scientific endeavors — particularly analytical instruments — are occurring rapidly, with interconnections to computers and data management systems becoming increasingly necessary. [8] [9]
Scientific instruments vary greatly in size, shape, purpose, complication and complexity. They include relatively simple laboratory equipment like scales, rulers, chronometers, thermometers, etc. Other simple tools developed in the late 20th century or early 21st century are the Foldscope (an optical microscope), the SCALE(KAS Periodic Table), [10] the MasSpec Pen (a pen that detects cancer), the glucose meter, etc. However, some scientific instruments can be quite large in size and significant in complexity, like particle colliders or radio-telescope antennas. Conversely, microscale and nanoscale technologies are advancing to the point where instrument sizes are shifting towards the tiny, including nanoscale surgical instruments, biological nanobots, and bioelectronics. [11] [12]
Instruments are increasingly based upon integration with computers to improve and simplify control; enhance and extend instrumental functions, conditions, and parameter adjustments; and streamline data sampling, collection, resolution, analysis (both during and post-process), and storage and retrieval. Advanced instruments can be connected as a local area network (LAN) directly or via middleware and can be further integrated as part of an information management application such as a laboratory information management system (LIMS). [13] [14] Instrument connectivity can be furthered even more using internet of things (IoT) technologies, allowing for example laboratories separated by great distances to connect their instruments to a network that can be monitored from a workstation or mobile device elsewhere. [15]
The dictionary definition of -tron at Wiktionary, a suffix to denote a complex scientific instrument, like in cyclotron, phytotron, synchrotron, ...
An optical spectrometer is an instrument used to measure properties of light over a specific portion of the electromagnetic spectrum, typically used in spectroscopic analysis to identify materials. The variable measured is most often the irradiance of the light but could also, for instance, be the polarization state. The independent variable is usually the wavelength of the light or a closely derived physical quantity, such as the corresponding wavenumber or the photon energy, in units of measurement such as centimeters, reciprocal centimeters, or electron volts, respectively.
The W. M. Keck Observatory is an astronomical observatory with two telescopes at an elevation of 4,145 meters (13,600 ft) near the summit of Mauna Kea in the U.S. state of Hawaii. Both telescopes have 10 m (33 ft) aperture primary mirrors, and, when completed in 1993 and 1996, they were the largest optical reflecting telescopes in the world. They have been the third and fourth largest since 2006.
The Michelson interferometer is a common configuration for optical interferometry and was invented by the 19/20th-century American physicist Albert Abraham Michelson. Using a beam splitter, a light source is split into two arms. Each of those light beams is reflected back toward the beamsplitter which then combines their amplitudes using the superposition principle. The resulting interference pattern that is not directed back toward the source is typically directed to some type of photoelectric detector or camera. For different applications of the interferometer, the two light paths can be with different lengths or incorporate optical elements or even materials under test.
Tweezers are small hand tools used for grasping objects too small to be easily handled with the human fingers. Tweezers are thumb-driven forceps most likely derived from tongs used to grab or hold hot objects since the dawn of recorded history. In a scientific or medical context, they are normally referred to as just "forceps", a name that is used together with other grasping surgical instruments that resemble pliers, pincers and scissors-like clamps.
Plate readers, also known as microplate readers or microplate photometers, are instruments which are used to detect biological, chemical or physical events of samples in microtiter plates. They are widely used in research, drug discovery, bioassay validation, quality control and manufacturing processes in the pharmaceutical and biotechnological industry and academic organizations. Sample reactions can be assayed in 1-1536 well format microtiter plates. The most common microplate format used in academic research laboratories or clinical diagnostic laboratories is 96-well with a typical reaction volume between 100 and 200 μL per well. Higher density microplates are typically used for screening applications, when throughput and assay cost per sample become critical parameters, with a typical assay volume between 5 and 50 μL per well. Common detection modes for microplate assays are absorbance, fluorescence intensity, luminescence, time-resolved fluorescence, and fluorescence polarization.
X-ray spectroscopy is a general term for several spectroscopic techniques for characterization of materials by using x-ray radiation.
Ames National Laboratory, formerly Ames Laboratory, is a United States Department of Energy national laboratory located in Ames, Iowa, and affiliated with Iowa State University. It is a top-level national laboratory for research on national security, energy, and the environment. The laboratory conducts research into areas of national concern, including the synthesis and study of new materials, energy resources, high-speed computer design, and environmental cleanup and restoration. It is located on the campus of Iowa State University.
The UCL Mullard Space Science Laboratory (MSSL) is the United Kingdom's largest university space research group. MSSL is part of the Department of Space and Climate Physics at University College London (UCL), one of the first universities in the world to conduct space research. Since its establishment, MSSL has participated in 35 satellite missions, 10 of which are currently in operation, and in over 200 sounding rocket experiments.
Hinode, formerly Solar-B, is a Japan Aerospace Exploration Agency Solar mission with United States and United Kingdom collaboration. It is the follow-up to the Yohkoh (Solar-A) mission and it was launched on the final flight of the M-V rocket from Uchinoura Space Center, Japan on 22 September 2006 at 21:36 UTC. Initial orbit was perigee height 280 km, apogee height 686 km, inclination 98.3 degrees. Then the satellite maneuvered to the quasi-circular Sun-synchronous orbit over the day/night terminator, which allows near-continuous observation of the Sun. On 28 October 2006, the probe's instruments captured their first images.
The European X-Ray Free-Electron Laser Facility is an X-ray research laser facility commissioned during 2017. The first laser pulses were produced in May 2017 and the facility started user operation in September 2017. The international project with twelve participating countries; nine shareholders at the time of commissioning, later joined by three other partners, is located in the German federal states of Hamburg and Schleswig-Holstein. A free-electron laser generates high-intensity electromagnetic radiation by accelerating electrons to relativistic speeds and directing them through special magnetic structures. The European XFEL is constructed such that the electrons produce X-ray light in synchronisation, resulting in high-intensity X-ray pulses with the properties of laser light and at intensities much brighter than those produced by conventional synchrotron light sources.
Rigaku Corporation is an international manufacturer and distributor of scientific, analytical and industrial instrumentation specializing in X-ray related technologies, including X-ray crystallography, X-ray diffraction (XRD), X-ray reflectivity, X-ray fluorescence (XRF), automation, cryogenics and X-ray optics.
The technique of vibrational analysis with scanning probe microscopy allows probing vibrational properties of materials at the submicrometer scale, and even of individual molecules. This is accomplished by integrating scanning probe microscopy (SPM) and vibrational spectroscopy. This combination allows for much higher spatial resolution than can be achieved with conventional Raman/FTIR instrumentation. The technique is also nondestructive, requires non-extensive sample preparation, and provides more contrast such as intensity contrast, polarization contrast and wavelength contrast, as well as providing specific chemical information and topography images simultaneously.
The following outline is provided as an overview of and topical guide to biophysics:
A spectrometer is a scientific instrument used to separate and measure spectral components of a physical phenomenon. Spectrometer is a broad term often used to describe instruments that measure a continuous variable of a phenomenon where the spectral components are somehow mixed. In visible light a spectrometer can separate white light and measure individual narrow bands of color, called a spectrum. A mass spectrometer measures the spectrum of the masses of the atoms or molecules present in a gas. The first spectrometers were used to split light into an array of separate colors. Spectrometers were developed in early studies of physics, astronomy, and chemistry. The capability of spectroscopy to determine chemical composition drove its advancement and continues to be one of its primary uses. Spectrometers are used in astronomy to analyze the chemical composition of stars and planets, and spectrometers gather data on the origin of the universe.
Robert Emmet Finnigan was an American pioneer in the development of gas chromatography–mass spectrometry equipment (GC/MS). Finnigan founded the Scientific Instruments Division of Electronic Associates, Inc., producing the first commercial quadrupole mass spectrometer in 1964. He then formed Finnigan Instruments Corporation to combine a computer system with a quadrupole mass spectrometer and gas chromatograph. Finnigan's GC/MS/computer systems are used to detect and identify trace organic compounds, making them important instruments for the monitoring and protection of the environment. They were adopted by the United States Environmental Protection Agency as a standard instrument for monitoring water quality and were fundamental to the work of the EPA.
Origins Space Telescope (Origins) is a concept study for a far-infrared survey space telescope mission. A preliminary concept in pre-formulation, it was presented to the United States Decadal Survey in 2019 for a possible selection to NASA's large strategic science missions. Origins would provide an array of new tools for studying star formation and the energetics and physical state of the interstellar medium within the Milky Way using infrared radiation and new spectroscopic capabilities.
John Michael Ramsey is an American analytical chemist at the University of North Carolina at Chapel Hill. He currently holds the position of Minnie N. Goldby Distinguished Professor of Chemistry. His current research with the university focuses on microscale and nanoscale devices such as microchip electrospray, microscale Ion trap mass spectrometers, and microfluidic point of care devices. He is ranked #2 in the "Giants of Nano" field on The Analytical Scientist Power List.
Michael Morris is an American biochemist, oceanographer and businessman, who has designed, developed and marketed new applications of optical sensing technology and spectroscopy. He has founded several companies including pHish Doctor, Ocean Optics Inc. (OOI), and SpectrEcology.
