Lassa fever, also known as Lassa hemorrhagic fever (LHF), is a type of viral hemorrhagic fever caused by the Lassa virus. Many of those infected by the virus do not develop symptoms. When symptoms occur they typically include fever, weakness, headaches, vomiting, and muscle pains. Less commonly there may be bleeding from the mouth or gastrointestinal tract. The risk of death once infected is about one percent and frequently occurs within two weeks of the onset of symptoms. Of those who survive, about a quarter have hearing loss, which improves within three months in about half of these cases.
Papillomaviridae is a family of non-enveloped DNA viruses whose members are known as papillomaviruses. Several hundred species of papillomaviruses, traditionally referred to as "types", have been identified infecting all carefully inspected mammals, but also other vertebrates such as birds, snakes, turtles and fish. Infection by most papillomavirus types, depending on the type, is either asymptomatic or causes small benign tumors, known as papillomas or warts. Papillomas caused by some types, however, such as human papillomaviruses 16 and 18, carry a risk of becoming cancerous.
The laboratory mouse or lab mouse is a small mammal of the order Rodentia which is bred and used for scientific research or feeders for certain pets. Laboratory mice are usually of the species Mus musculus. They are the most commonly used mammalian research model and are used for research in genetics, psychology, medicine and other scientific disciplines. Mice belong to the Euarchontoglires clade, which includes humans. This close relationship, the associated high homology with humans, their ease of maintenance and handling, and their high reproduction rate, make mice particularly suitable models for human-oriented research. The laboratory mouse genome has been sequenced and many mouse genes have human homologues.
The Old World rats and mice, part of the subfamily Murinae in the family Muridae, comprise at least 519 species. Members of this subfamily are called murines. In terms of species richness, this subfamily is larger than all mammal families except the Cricetidae and Muridae, and is larger than all mammal orders except the bats and the remainder of the rodents.
The blesmols, also known as mole-rats, or African mole-rats, are burrowing rodents of the family Bathyergidae. They represent a distinct evolution of a subterranean life among rodents much like the pocket gophers of North America, the tuco-tucos in South America, or the Spalacidae.
The Awash multimammate mouse or Awash mastomys is a species of rodent in the family Muridae found only in Ethiopia. Phylogentically the Awash multimammate mouse is the sister taxon of the Natal multimammate mouse, a species found almost everywhere in Africa south of the Sahara and considered a serious agricultural pest throughout its range.
Mastomys is a genus of rodent in the family Muridae endemic to Africa. It contains these species:
The Guinea multimammate mouse is a species of rodent in the family Muridae found in Benin, Burkina Faso, Burundi, Cameroon, the Central African Republic, Chad, the Republic of the Congo, the Democratic Republic of the Congo, Ivory Coast, Ethiopia, Gambia, Ghana, Guinea, Guinea-Bissau, Kenya, Liberia, Mali, Mauritania, Morocco, Niger, Nigeria, Rwanda, Senegal, Sierra Leone, Sudan, Togo, and Uganda. Its natural habitats are subtropical or tropical dry forests, dry savanna, moist savanna, subtropical or tropical dry shrubland, subtropical or tropical moist shrubland, arable land, rural gardens, urban areas, and irrigated land. They weigh between 12 and 105 grams.
The Natal multimammate mouse is a species of rodent in the family Muridae. It is also known as the Natal multimammate rat, the common African rat, or the African soft-furred mouse.
The dwarf multimammate mouse is a species of rodent in the family Muridae. It is the only member of the genus Serengetimys; it was formerly classified in the genus Mastomys.
Shortridge's multimammate mouse is a rodent species in the family Muridae. It is native to Angola, Botswana and Namibia. Its natural habitats are moist savanna, subtropical or tropical seasonally wet or flooded lowland grassland, and swamps.
The Angolan multimammate mouse is a species of rodent in the family Muridae. It is found in Angola and Democratic Republic of the Congo. It was formerly classified in the genus Myomyscus but has been reclassified into the genus Mastomys. Its natural habitats are dry savanna and moist savanna.
The tiny fat mouse is a species of rodent in the family Nesomyidae. It is found in Angola, Botswana, Ethiopia, Kenya, Mozambique, Namibia, South Sudan, Tanzania, Uganda, Zambia, and Zimbabwe. Its natural habitats are subtropical or tropical dry shrubland and subtropical or tropical dry lowland grassland.
Rodents are commonly used in animal testing, particularly mice and rats, but also guinea pigs, hamsters, gerbils and others. Mice are the most commonly used vertebrate species, due to their availability, size, low cost, ease of handling, and fast reproduction rate.
A humanized mouse is a mouse carrying functioning human genes, cells, tissues, and/or organs. Humanized mice are commonly used as small animal models in biological and medical research for human therapeutics.
A robovirus is a zoonotic virus that is transmitted by a rodent vector.
Pterygodermatites peromysci is an intestinal parasitic nematode in the genus Pterygodermatites of the family Rictulariidae.
Morogoro virus is an East African arenavirus infecting the multimammate mouse. The virus is genetically closely related to Lassa virus, known to cause Lassa fever in humans. Morogoro virus, however, does not seem to infect humans. Transmission of Morogoro virus between mice is assumed to occur via direct and indirect contact. Infected animals pass a latent period of 7 days and subsequently shed the virus for about 30 days, after which they recover and develop lifelong antibodies. Transmission may also be possible from infected mothers to offspring and through sexual contact, as this has been suggested for other arenaviruses.
