Stephania

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Stephania
Stephania cephalantha Yu Xiao Ge Teng  (Tian Wen ) 001.jpg
Stephania cephalantha
Scientific classification OOjs UI icon edit-ltr.svg
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Order: Ranunculales
Family: Menispermaceae
Genus: Stephania
Lour.

Stephania is a genus of flowering plants in the family Menispermaceae, native to eastern and southern Asia and Australia. They are herbaceous perennial vines, growing to around four metres tall, with a large tuber. The leaves are arranged spirally on the stem and are peltate, with the leaf petiole attached near the centre of the leaf. The name Stephania comes from the Greek, "a crown". This refers to the anthers being arranged in a crown-like manner. [1]

Contents

One species, S. tetrandra , is among the 50 fundamental herbs used in traditional Chinese medicine, where it is called han fang ji (漢防己, "Chinese fang ji"). Other plants named fang ji are sometimes substituted for it. Other varieties substituted include Cocculus thunbergii , C. trulobus , Aristolochia fangchi , Stephania tetrandria , and Sinomenium acutum . Notable among these is guang fang ji (廣防己, "(GuangDong, GuangXi) fang ji", Aristolochia fangchi. Because of its toxicity, it is used in TCM only with great caution.

Selected species

There are about 45 species in the genus Stephania, native to the Far East and Australasia. [2] Species include: [3]

Fossil species
Synonyms

Toxicity

Female flowers of Stephania delavayi Stephania-delavayi Menispermaceae flowers.jpg
Female flowers of Stephania delavayi

There is evidence that a few species of Stephania are toxic. [5] However, the most commonly available species in the United States, Stephania tetrandra , has not been shown to be toxic. Any confusion regarding the possible toxicity of Stephania tetrandra was entirely due to an inadvertent shipment of Aristolochia fangchi sent in its stead to a Belgian clinic in 1993. The errant batch of Aristolochia was later confirmed via phytochemical analysis. [6]

Chemistry

Chemical investigation of Stephania rotunda Lour. growing in Vietnam in 2005 led to the isolation and structural elucidation of three new alkaloids, 5-hydroxy-6,7-dimethoxy-3,4-dihydroisoquinolin-1(2H)-one, thaicanine 4-O-beta-D-glucoside, as well as (−)-thaicanine N-oxide (4-hydroxycorynoxidine), along with 23 known alkaloids. [7]

Related Research Articles

<span class="mw-page-title-main">Aristolochiaceae</span> Family of flowering plants

The Aristolochiaceae are a family, the birthwort family, of flowering plants with seven genera and about 400 known species belonging to the order Piperales. The type genus is Aristolochia L.

<i>Menispermum</i> Genus of flowering plants

Menispermum (moonseed) is a small genus of deciduous climbing woody vines in the moonseed family (Menispermaceae). Plants in this genus have small dioecious flowers, and clusters of small grape-like drupes. The name, moonseed, comes from the shape of the seed, which resembles a crescent moon. The word Menispermum is derived from the Greek words μήν (mēn), meaning (crescent) moon, and σπέρμα (sperma) meaning seed. The common name moonseed is also applied to some other species in the related genus Cocculus.

<i>Aristolochia</i> Genus of plants in the family Aristolochiaceae

Aristolochia is a large plant genus with over 500 species that is the type genus of the family Aristolochiaceae. Its members are commonly known as birthwort, pipevine or Dutchman's pipe and are widespread and occur in the most diverse climates. Some species, like A. utriformis and A. westlandii, are threatened with extinction.

<i>Olea</i> Genus of flowering plants

Olea is a genus of about 40 species in the family Oleaceae, native to warm temperate and tropical regions of the Middle East, southern Europe, Africa, southern Asia, and Australasia. They are evergreen trees and shrubs, with small, opposite, entire leaves. The fruit is a drupe. Leaves of Olea contain trichosclereids.

<i>Sanguinaria</i> Genus of flowering plants in the poppy family Papaveraceae

Sanguinaria canadensis, bloodroot, is a perennial, herbaceous flowering plant native to eastern North America. It is the only species in the genus Sanguinaria, included in the poppy family Papaveraceae, and is most closely related to Eomecon of eastern Asia.

<span class="mw-page-title-main">Menispermaceae</span> Family of flowering plants

Menispermaceae is a family of flowering plants. The alkaloid tubocurarine, a neuromuscular blocker and the active ingredient in the 'tube curare' form of the dart poison curare, is derived from the South American liana Chondrodendron tomentosum. Several other South American genera belonging to the family have been used to prepare the 'pot' and 'calabash' forms of curare. The family contains 68 genera with some 440 species, which are distributed throughout low-lying tropical areas with some species present in temperate and arid regions.

<i>Stemona</i> Genus of vines

Stemona is a genus of vines and subshrubs in the family Stemonaceae, described as a genus in 1790.

<i>Aristolochia rotunda</i> Species of vine

Aristolochia rotunda, commonly known as smearwort or round-leaved birthwort, is a herbaceous perennial plant native to Southern Europe.

<i>Eomecon</i> Genus of flowering plants

Eomecon is a monotypic genus of flowering plants in the poppy family containing the single species Eomecon chionantha. Its common names include snow-poppy and dawn-poppy. It is native to China.

<i>Lasianthus</i> Genus of flowering plants

Lasianthus is a genus of flowering plants in the family Rubiaceae. They are tropical subshrubs, shrubs, or rarely, small trees. They inhabit the understory of primary forests.

Stephania tetrandra is a herbaceous perennial vine of the family Menispermaceae native to China and Taiwan. It grows from a short, woody caudex, climbing to a height of around three meters. The leaves are arranged spirally on the stem, and are peltate, i.e. with the leaf petiole attached near the centre of the leaf. Its root is used in traditional Chinese medicine (TCM).

<i>Blumea</i> Genus of flowering plants

Blumea is a genus of flowering plants of the family Asteraceae.

<i>Chondrodendron tomentosum</i> Species of flowering plant

Chondrodendron tomentosum is one of six accepted species in the small genus Chondrodendron, belonging to the Moonseed family Menispermaceae. It is a large tropical liana native to Central and South America. It contains highly toxic alkaloids and is one of the sources of the arrow poison curare - specifically 'tube curare', the name of which is derived from the name of the medicinally valuable alkaloid tubocurarine.

<i>Anisomeles</i> Genus of flowering plants

Anisomeles is a genus of herbs of the family Lamiaceae and is native to China, the Indian Subcontinent, Southeast Asia, New Guinea, Australia, Madagascar, and some Pacific and Indian Ocean islands. Plants in the genus Anisomeles have small, flat, narrow elliptic to narrow e.g.-shaped leaves arranged in opposite pairs, the edges of the leaves sometimes wavy or serrated. The flowers are arranged in groups, with five sepals and five petals in two "lips", the lower lip with three lobes, the middle lobe much longer than the side lobes. There are four stamens that extend beyond the petals and a single style in a depression on top of the ovary. The fruit is a schizocarp with four nutlets containing small seeds.

<i>Aristolochia didyma</i> Species of vine

Aristolochia didyma, or yawar panga is a plant found in South America of the genus Aristolochia. It is a powerful purgative, sometimes used in traditional rites to purify the body a few days before an Ayahuasca session.

Stephania crebra is a herbaceous perennial vine in the genus Stephania of the family Menispermaceae. It is native to Southeast Asia and was first described in Thailand in 1988 by L. L. Forman. It is one of 15 Stephania found only in northern Thailand, specifically in the province of Chiang Mai. It has leaves 12–17 cm (4.7–6.7 in) long and 9–16 cm (3.5–6.3 in) wide. It resembles Stephania reticulata but S. crebra has larger flowers but smaller drupes and endocarps.

<i>Crotalaria retusa</i> Species of plant

Crotalaria retusa is a species of flowering plant in the legume family known by various common names including devil-bean, rattleweed, shack shack, and wedge-leaf rattlepod. It is poisonous to livestock, and contaminates human food. Its original native range is unclear, probably including tropical Asia, Africa and Australia. It has been introduced as a crop plant in many tropical areas and has escaped from cultivation to become a troublesome weed; it is listed as a noxious weed in several US states, Puerto Rico, the Virgin Islands, and is listed as an invasive weed in India, Cuba, and Cocos Island. Unlike some other species of Crotalaria, it is an annual plant.

Aristolochia fangchi, is a species of flowering plant in the family Aristolochiaceae, native to Vietnam and southeast and south-central China.

<i>Stephania cephalantha</i> Species of plant

Stephania cephalantha is a plant in the genus Stephania of the family Menispermaceae native to China, Taiwan and Vietnam.

Stephania pierrei, also known as Stephania erecta or binh voi in Vietnamese, is a caudiciform vine native to the Indo-Chinese Peninsula. It is cultivated as a houseplant; in commerce it is typically described as Stephania erecta. It was first described by Ludwig Diels in 1910. The root or caudex is used medicinally in Vietnam; the 2006 Vietnam Red List of Medicinal Plants lists Stephania pierrei as a vulnerable species within the country.

References

  1. Les Robinson (2003). Field Guide to the Native Plants of Sydney. p. 336. ISBN   978-0-7318-1211-0.
  2. Forman, L. L. (1988). "A Synopsis of Thai Menispermaceae". Kew Bulletin. Royal Botanic Gardens, Kew. 43 (3): 369–407. doi:10.2307/4118970. JSTOR   4118970.
  3. GRIN. "GRIN Species Records of genus Stephania". Taxonomy for Plants. National Germplasm Resources Laboratory, Beltsville, Maryland: USDA, ARS, National Genetic Resources Program. Retrieved September 29, 2013.
  4. William Grant Craib, Bull. Misc. Inform. Kew 1922(8): 229, 1922. http://biodiversitylibrary.org/page/11492328
  5. Journal of Ethnopharmacology 132 (2010). p. 380
  6. Nunez, Kelvin R. (2006). Trends in Kidney Cancer Research. Vol. 18. Hauppauge, New York: Nova Science Publishers. p. 78. ISBN   1-59454-141-8.
  7. Thuy, T. T; Porzel, A.; Franke, K.; Wessjohann, L.; Sung, T. V. (September 2005). "Isoquinolone and protoberberine alkaloids from Stephania rotunda". Die Pharmazie. 60 (9): 701–704. PMID   16222872.