Polio vaccines are vaccines used to prevent poliomyelitis (polio). Two types are used: an inactivated poliovirus given by injection (IPV) and a weakened poliovirus given by mouth (OPV). The World Health Organization (WHO) recommends all children be fully vaccinated against polio. The two vaccines have eliminated polio from most of the world, and reduced the number of cases reported each year from an estimated 350,000 in 1988 to 33 in 2018.
March of Dimes is a United States nonprofit organization that works to improve the health of mothers and babies. The organization was founded by President Franklin D. Roosevelt in 1938, as the National Foundation for Infantile Paralysis, to combat polio. The name "March of Dimes" was coined by Eddie Cantor. After funding Jonas Salk's polio vaccine, the organization expanded its focus to the prevention of birth defects and infant mortality. In 2005, as preterm birth emerged as the leading cause of death for children worldwide, research and prevention of premature birth became the organization's primary focus.
Albert Bruce Sabin was a Polish-American medical researcher, best known for developing the oral polio vaccine, which has played a key role in nearly eradicating the disease. In 1969–72, he served as the president of the Weizmann Institute of Science in Israel.
Leonard Andrew Scheele was an American physician and public servant. He was appointed the seventh Surgeon General of the United States from 1948 to 1956.
Herald Rea Cox (1907–1986) was an American bacteriologist. The bacterial family Coxiellaceae and the genus Coxiella, which include the organism that causes Q fever, are named after him.
Parke-Davis is a subsidiary of the pharmaceutical company Pfizer. Although Parke, Davis & Co. is no longer an independent corporation, it was once America's oldest and largest drug maker, and played an important role in medical history. In 1970 Parke-Davis was acquired by Warner–Lambert, which in turn was acquired by Pfizer in 2000.
The Michigan Daily, also known as 'The Daily,' is the independent student newspaper of the University of Michigan published in Ann Arbor, Michigan. Established on September 29, 1890, the newspaper is financially as well as editorially independent from the university. The Daily is managed by two editors-in-chief and a business manager who oversee a staff of over 500 undergraduate students.
Thomas Francis Jr. was an American physician, virologist, and epidemiologist who guided the discovery and development of the polio vaccine being worked on by his student Jonas Salk. Francis was the first person to isolate influenza virus in the United States, and in 1940 showed that there are other strains of influenza, and took part in the development of influenza vaccines.
University of Michigan Medicine is the academic medical center of the University of Michigan in Ann Arbor. It consists of the University of Michigan Medical School, university hospitals, and affiliated healthcare centers.
The Wayne State University School of Medicine (WSUSOM) is the medical school of Wayne State University, a public research university in Detroit, Michigan. It enrolls more than 1,500 students in undergraduate medical education, master's degree, Ph.D., and M.D.-Ph.D. WSUSOM traces its roots through four predecessor institutions since its founding in 1868.
The University of Michigan College of Pharmacy is the pharmacy school of the University of Michigan. Situated on the university's central campus in Ann Arbor, Michigan, the school is tied for the third-ranked pharmacy school in the United States as of 2023.
The history of polio (poliomyelitis) infections began during prehistory. Although major polio epidemics were unknown before the 20th century, the disease has caused paralysis and death for much of human history. Over millennia, polio survived quietly as an endemic pathogen until the 1900s when major epidemics began to occur in Europe. Soon after, widespread epidemics appeared in the rest of the world. By 1910, frequent epidemics became regular events throughout the developed world primarily in cities during the summer months. At its peak in the 1940s and 1950s, polio would paralyze or kill over half a million people worldwide every year.
Jonas Edward Salk was an American virologist and medical researcher who developed one of the first successful polio vaccines. He was born in New York City and attended the City College of New York and New York University School of Medicine.
The University of Michigan Institute for Social Research (ISR) is the largest academic social research and survey organization in the world, established in 1949. ISR includes more than 300 scientists from a variety of academic disciplines – including political science, psychology, sociology, economics, demography, history, anthropology, and statistics. The institute is a unit that houses five separate but interdependent centers which conduct research and maintain data archives. In 2021, Kathleen Cagney became the first woman in its history to be named Director of the institute.
Herbert Spencer Ratner, was an American physician. He taught and wrote on the philosophy and history of medicine and was a popular lecturer on marriage and the family. Ratner was the director of public health for the community of Oak Park, Illinois, for twenty-five years. An advocate of preventive family medicine based on natural norms, he was also a long-time proponent of informed medical consent, and played a pivotal role in the polio vaccine controversy beginning in 1955. For more than twenty-nine years Ratner was editor of Child and Family Quarterly, a paramedical journal which ran articles on the Hippocratic Oath, infant development, women’s health, and other topics related to family health.
The University of Michigan School of Social Work is a professional school within the University of Michigan located in Ann Arbor, Michigan.
Henry Frieze Vaughan was an American epidemiologist with a strong discipline in environmental health, an academic professor, and an administrator. Among the positions he held, he was the Health Commissioner for the City of Detroit (1919–1941), editor for “American Journal of Public Health” (1922–1924), President of American Public Health in 1925, trustee of the W. K. Kellogg Foundation (1933–1978), President of Council at the Michigan Department of Council (1939–1960), founder and Dean of the University of Michigan School of Public Health (1941–1960), and the co-founder and first president of the National Sanitation Foundation (1944–1966). Vaughan was born in Michigan and stayed in Michigan for most of his life contributing to the development and innovation of medical and health services in Michigan.
Howard Atkinson Howe was an American physician, whose work at the Johns Hopkins medical institutions helped to lay the groundwork for the Salk polio vaccine.
Herdis von Magnus was a Danish virologist and polio expert. After working with Jonas Salk, she and her husband directed the first polio vaccination program in Denmark. She also researched encephalitis.
The announcement of the polio vaccine's safety and effectiveness was on April 12, 1955, by Thomas Francis, Jr., of the University of Michigan, the monitor of the test results. Within minutes of his announcement to the audience of scientists and reporters, news of the event was carried coast to coast by wire services and radio and television newscasts. When the vaccine was announced as successful, it led to spontaneous celebrations across the United States. It was the world's first successful polio vaccine, declared "safe, effective, and potent." It was possibly the most significant biomedical advance of the past century.
