MYO1B

MYO1B
Identifiers
Aliases	MYO1B , myr1, myosin IB, MMIa, MMI-alpha, MYH-1c
External IDs	OMIM: 606537 MGI: 107752 HomoloGene: 7856 GeneCards: MYO1B
Gene location (Human)
Chr.	Chromosome 2 (human)
End	191,425,389 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	51,955,230 bp
RNA expression pattern
	Top expressed in
	visceral pleura; ; liver; ; right lobe of liver; ; islet of Langerhans; ; lower lobe of lung; ; right lung; ; hair follicle; ; stromal cell of endometrium; ; tibia; ; parietal pleura;
	Top expressed in
	right lung; ; lens; ; right lung lobe; ; seminal vesicula; ; left lung; ; left lobe of liver; ; calvaria; ; sciatic nerve; ; maxillary prominence; ; ganglionic eminence;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding ; calmodulin binding ; microfilament motor activity ; actin binding ; phosphatidylinositol-4,5-bisphosphate binding ; cytoskeletal motor activity ; ATP binding ; phosphatidylinositol-3,4,5-trisphosphate binding ; actin filament binding ; cadherin binding ;
Cellular component	cytoplasm ; trans-Golgi network membrane ; filopodium ; early endosome ; brush border ; actin filament ; perinuclear region of cytoplasm ; endosome membrane ; extracellular exosome ; cell periphery ; myosin complex ; plasma membrane ; apical part of cell ;
Biological process	actin filament organization ; actin filament-based movement ; actin filament bundle assembly ; post-Golgi vesicle-mediated transport ;
	Sources:Amigo / QuickGO
Orthologs
	4430
	17912
	ENSG00000128641
	ENSMUSG00000018417
	O43795
	P46735
	NM_001130158 ; NM_001161819 ; NM_012223 ; NM_001330237 ; NM_001330238
	NM_001161817 ; NM_001290982 ; NM_010863
	NP_001123630 ; NP_001155291 ; NP_001317166 ; NP_001317167 ; NP_036355
	NP_001155289 ; NP_001277911 ; NP_034993
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated April 12, 2024

Myosin-Ib is a protein that in humans is encoded by the MYO1B gene.^[5]^[6]^[7]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000128641 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000018417 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Bement WM, Hasson T, Wirth JA, et al. (Aug 1994). "Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types". Proc Natl Acad Sci U S A. 91 (14): 6549–53. Bibcode:1994PNAS...91.6549B. doi: 10.1073/pnas.91.14.6549 . PMC 44240 . PMID 8022818.
↑ Ruppert C, Kroschewski R, Bahler M (Apr 1993). "Identification, characterization and cloning of myr 1, a mammalian myosin-I". J Cell Biol. 120 (6): 1393–403. doi:10.1083/jcb.120.6.1393. PMC 2119751 . PMID 8449985.
↑ "Entrez Gene: MYO1B myosin IB".

Ruppert C, Godel J, Müller RT, et al. (1997). "Localization of the rat myosin I molecules myr 1 and myr 2 and in vivo targeting of their tail domains". J. Cell Sci. 108 (12): 3775–86. doi:10.1242/jcs.108.12.3775. PMID 8719884.
Tang N, Ostap EM (2001). "Motor domain-dependent localization of myo1b (myr-1)". Curr. Biol. 11 (14): 1131–5. Bibcode:2001CBio...11.1131T. doi: 10.1016/S0960-9822(01)00320-7 . PMID 11509238. S2CID 2678512.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Dumont RA, Zhao YD, Holt JR, et al. (2003). "Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia". J. Assoc. Res. Otolaryngol. 3 (4): 375–89. doi:10.1007/s101620020049. PMC 3202438 . PMID 12486594.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Salas-Cortes L, Ye F, Tenza D, et al. (2006). "Myosin Ib modulates the morphology and the protein transport within multi-vesicular sorting endosomes". J. Cell Sci. 118 (Pt 20): 4823–32. doi:10.1242/jcs.02607. PMID 16219689. S2CID 14698224.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948 . PMID 17353931.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000128641 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000018417 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8022818-5] Bement WM, Hasson T, Wirth JA, et al. (Aug 1994). "Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types". Proc Natl Acad Sci U S A. 91 (14): 6549–53. Bibcode:1994PNAS...91.6549B. doi: 10.1073/pnas.91.14.6549 . PMC 44240 . PMID 8022818.

[pmid8449985-6] Ruppert C, Kroschewski R, Bahler M (Apr 1993). "Identification, characterization and cloning of myr 1, a mammalian myosin-I". J Cell Biol. 120 (6): 1393–403. doi:10.1083/jcb.120.6.1393. PMC 2119751 . PMID 8449985.

[entrez-7] "Entrez Gene: MYO1B myosin IB".

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MYO1B

Related Research Articles

References

Further reading