2-dehydropantoate aldolase

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2-dehydropantoate aldolase
Identifiers
EC no. 4.1.2.12
CAS no. 9024-51-5
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The enzyme 2-dehydropantoate aldolase (EC 4.1.2.12) catalyzes the chemical reaction:

2-dehydropantoate 3-methyl-2-oxobutanoate + formaldehyde

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-dehydropantoate formaldehyde-lyase (3-methyl-2-oxobutanoate-forming). Other names in common use include ketopantoaldolase, and 2-dehydropantoate formaldehyde-lyase.

Related Research Articles

2-Hydroxyphytanoyl-CoA lyase is a peroxisomal enzyme involved in the catabolism of phytanoic acid by α-oxidation. It requires thiamine diphosphate (ThDP) as cofactor.

<span class="mw-page-title-main">Cystathionine gamma-lyase</span> Protein-coding gene in the species Homo sapiens

The enzyme cystathionine γ-lyase (EC 4.4.1.1, CTH or CSE; also cystathionase; systematic name L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming)) breaks down cystathionine into cysteine, 2-oxobutanoate (α-ketobutyrate), and ammonia:

The enzyme homocysteine desulfhydrase (EC 4.4.1.2) catalyzes the chemical reaction

<span class="mw-page-title-main">Methionine gamma-lyase</span>

The enzyme methionine γ-lyase (EC 4.4.1.11, MGL) is in the γ-family of PLP-dependent enzymes. It degrades sulfur-containing amino acids to α-keto acids, ammonia, and thiols:

The enzyme S-(hydroxymethyl)glutathione synthase catalyzes the reaction

<span class="mw-page-title-main">Threonine ammonia-lyase</span>

Threonine ammonia-lyase (EC 4.3.1.19, systematic name L-threonine ammonia-lyase (2-oxobutanoate-forming), also commonly referred to as threonine deaminase or threonine dehydratase, is an enzyme responsible for catalyzing the conversion of L-threonine into α-ketobutyrate and ammonia:

In enzymology, a 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) is an enzyme that catalyzes the chemical reaction

The enzyme 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase (EC 4.1.1.51) catalyzes the chemical reaction

The enzyme 3-hydroxy-3-isohexenylglutaryl-CoA lyase catalyzes the chemical reaction

The enzyme 4-hydroxy-4-methyl-2-oxoglutarate aldolase catalyzes the chemical reaction

The enzyme acetolactate decarboxylase (EC 4.1.1.5) catalyzes the chemical reaction

The enzyme branched-chain-2-oxoacid decarboxylase (EC 4.1.1.72) catalyzes the chemical reaction

The enzyme dimethylaniline-N-oxide aldolase catalyzes the chemical reaction

The enzyme ketotetrose-phosphate aldolase catalyzes the chemical reaction

The enzyme trimethylamine-oxide aldolase catalyzes the chemical reaction

The enzyme dihydroxy-acid dehydratase (EC 4.2.1.9) catalyzes the chemical reaction

In enzymology, a 2-ethylmalate synthase (EC 2.3.3.6) is an enzyme that catalyzes the chemical reaction

In enzymology, a 2-isopropylmalate synthase (EC 2.3.3.13) is an enzyme that catalyzes the chemical reaction

In enzymology, a [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] is an enzyme that catalyzes the chemical reaction

(3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring))-phosphatase (EC 3.1.3.52, branched-chain oxo-acid dehydrogenase phosphatase, branched-chain 2-keto acid dehydrogenase phosphatase, branched-chain α-keto acid dehydrogenase phosphatase, BCKDH', [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase, [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphate phosphohydrolase) is an enzyme with systematic name (3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring))-phosphate phosphohydrolase. This enzyme catalyses the following chemical reaction

References


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