Anne Ridley

Last updated

Anne Ridley

Anne Ridley Royal Society.jpg
Anne Ridley at the Royal Society admissions day in London, July 2017
Born
Anne Jacqueline Ridley

1963 (age 5960) [1]
Alma mater University of Cambridge (BA)
University of London (PhD)
Awards
Scientific career
Fields
Institutions
Thesis Mechanisms of oncogene action and interaction in Schwann cells  (1989)
Doctoral advisor Hartmut Land [4]
Website research-information.bristol.ac.uk/en/persons/anne-j-ridley(68d1bf7e-4a1b-4bcb-abd8-316e35f5f768).html

Anne Jacqueline Ridley (born 1963) [1] FRS FRSB FMedSci FRMS [3] is professor of Cell Biology and Head of School for Cellular and Molecular Medicine at the University of Bristol. She was previously a professor at King's College London. [5] [4] [6] [7] [8]

Contents

Education

Ridley was educated at Clare College, Cambridge [1] and awarded a Bachelor of Arts degree in Natural Sciences (Biochemistry) from the University of Cambridge in 1985. After being encouraged by Tim Hunt to pursue a career in research [9] she moved to the University of London where she was awarded a Doctor of Philosophy degree in 1989 [10] for research investigating the regulation of oncogenes in Schwann cells supervised by Hartmut Land [9] [11] [12] at the Imperial Cancer Research Fund.

Career and research

Ridley started her career as a postdoctoral researcher at the Whitehead Institute in Cambridge, Massachusetts from 1989 to 1990 and the Institute of Cancer Research in London from 1990 to 1993. She was appointed research group leader at the Ludwig Institute for Cancer Research at University College London (UCL) from 1993 to 2007 and Professor of Cell Biology at UCL from 2003 to 2007.

Since 2007, she has been Professor at King's College London [6] and her research has made contributions to our understanding of cancer, tumour progression and inflammation through her work on cell migration and the Rho family of GTPases. [13] [14] [15] [16]

Work in her laboratory [17] [18] [19] has influenced many areas of medical science, from metastasis to cardiovascular disease and infection. Funding for her research has been provided by the Biotechnology and Biological Sciences Research Council (BBSRC), the Medical Research Council (MRC), [20] Cancer Research UK (CRUK) and Worldwide Cancer Research. [7] [21]

Awards and honours

Ridley was elected a Fellow of the Royal Society (FRS) in 2017. [3] She was also awarded the Robert Hooke Medal by the British Society of Cell Biology (BSCB) in 2000, [3] EMBO Membership in 2002 [2] and the Liliane Bettencourt Prize for the Life Sciences in 2004. [3] She was elected a Fellow of the Royal Society of Biology (FRSB) in 2009 and a Fellow of the Academy of Medical Sciences (FMedSci) in 2012. [3] She became an honorary fellow of the Royal Microscopical Society (FRMS) in 2014. [3]

Related Research Articles

Christopher John Leaver is an Emeritus Professorial Fellow of St John's College, Oxford who served as Sibthorpian Professor in the Department of Plant Sciences at the University of Oxford from 1990 to 2007.

Christopher John Marshall FRS FMedSci was a British scientist who worked as director of the Division for Cancer Biology at the Institute of Cancer Research. Marshall was distinguished for research in the field of tumour cell signalling. His track record includes the discovery of the N-Ras oncogene , the identification of farnesylation of Ras proteins, and the discovery that Ras signals through the MAPK/ERK pathway. These findings have led to therapeutic development of inhibitors of Ras farnesylation, MEK and B-Raf.

Frances Rosemary Balkwill is an English scientist, Professor of Cancer Biology at Queen Mary University of London, and author of children's books about scientific topics.

<span class="mw-page-title-main">Cathie Martin</span> British botanist

Catherine Rosemary Martin is a Professor of Plant Sciences at the University of East Anglia (UEA) and project leader at the John Innes Centre, Norwich, co-ordinating research into the relationship between diet and health and how crops can be fortified to improve diets and address escalating chronic disease globally.

<span class="mw-page-title-main">Jim Cuthbert Smith</span>

Sir James Cuthbert Smith is Director of Science at the Wellcome Trust, Senior Group Leader at the Francis Crick Institute and President of the Council at Zoological Society of London.

<span class="mw-page-title-main">Sarah Teichmann</span> German bioinformatician

Sarah Amalia Teichmann is a German scientist who is head of cellular genetics at the Wellcome Sanger Institute and a visiting research group leader at the European Bioinformatics Institute (EMBL-EBI). She serves as director of research in the Cavendish Laboratory, at the University of Cambridge and a senior research fellow at Churchill College, Cambridge.

<span class="mw-page-title-main">Wendy Bickmore</span> British genome biologist (born 1961)

Wendy Anne Bickmore is a British genome biologist known for her research on the organisation of genomic material in cells.

William Charles Earnshaw is Professor of Chromosome Dynamics at the University of Edinburgh where he has been a Wellcome Trust Principal Research Fellow since 1996.

<span class="mw-page-title-main">Christine Orengo</span> Professor of Bioinformatics

Christine Anne Orengo is a Professor of Bioinformatics at University College London (UCL) known for her work on protein structure, particularly the CATH database. Orengo serves as president of the International Society for Computational Biology (ISCB), the first woman to do so in the history of the society.

<span class="mw-page-title-main">Jonathon Pines</span> British oncologist (born 1961)

Jonathon Noë Joseph Pines is Head of the Cancer Biology Division at the Institute of Cancer Research in London. He was formerly a senior group leader at the Gurdon Institute at the University of Cambridge.

<span class="mw-page-title-main">Josephine Pemberton</span> British evolutionary biologist

Josephine M. Pemberton is a British evolutionary biologist. She is Chair of Natural History at the University of Edinburgh, where she conducts research in parentage analysis, pedigree reconstruction, inbreeding depression, parasite resistance, and quantitative trait locus (QTL) detection in natural populations. She has worked primarily on long-term studies of soay sheep on St Kilda, and red deer on the island of Rùm.

<span class="mw-page-title-main">E. Yvonne Jones</span> Director of the Cancer Research UK Receptor Structure Research Group

(Edith) Yvonne JonesFLSW is director of the Cancer Research UK Receptor Structure Research Group at the University of Oxford and a Fellow of Jesus College, Oxford. She is widely known for her research on the molecular biology of cell surface receptors and signalling complexes.

<span class="mw-page-title-main">Alison Noble</span> British engineer (born 1965)

Julia Alison Noble is a British engineer. She has been Technikos Professor of Biomedical Engineering at the University of Oxford and a fellow of St Hilda's College since 2011, and Associate Head of the Mathematical, Physical and Life Sciences Division at the university. As of 2017, she is the chief technology officer of Intelligent Ultrasound Limited, an Oxford spin-off in medical imaging that she cofounded. She was director of the Oxford Institute of Biomedical Engineering (IBME) from 2012 to 2016.In 2023 she became the Foreign Secretary of The Royal Society.

James Briscoe is a senior group leader at the Francis Crick Institute in London and editor-in-chief of the journal Development.

<span class="mw-page-title-main">Richard Marais</span> Cancer researcher

Richard Malcolm Marais is Director of the Cancer Research UK (CRUK) Manchester Institute and Professor of Molecular Oncology at the University of Manchester.

<span class="mw-page-title-main">Richard Treisman</span> British scientist

Sir Richard Henry Treisman is a British scientist specialising in the molecular biology of cancer. Treisman is a director of research at the Francis Crick Institute in London.

<span class="mw-page-title-main">Neil Brockdorff</span> British biochemist (born 1958)

Neil Alexander Steven Brockdorff is a Wellcome Trust Principal Research Fellow and professor in the department of biochemistry at the University of Oxford. Brockdorff's research investigates gene and genome regulation in mammalian development. His interests are in the molecular basis of X-inactivation, the process that evolved in mammals to equalise X chromosome gene expression levels in XX females relative to XY males.

<span class="mw-page-title-main">Charles Swanton</span>

(Robert) Charles Swanton is British physician scientist specialising in oncology and cancer research. Swanton is a senior group leader at London's Francis Crick Institute, Royal Society Napier Professor in Cancer and thoracic medical oncologist at University College London and University College London Hospitals, co-director of the Cancer Research UK (CRUK) Lung Cancer Centre of Excellence, and Chief Clinician of Cancer Research UK.

<span class="mw-page-title-main">Sean Munro</span> British biologist

Sean Munro is a Group Leader at the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB). From 2012 until 2023, he served as Head of the Cell Biology Division.

Caetano Maria Pacheco Pais dos Reis e Sousa is a senior group leader at the Francis Crick Institute and a professor of Immunology at Imperial College London.

References

  1. 1 2 3 Anon (2017). "RIDLEY, Prof. Anne Jacqueline" . Who's Who (online Oxford University Press  ed.). Oxford: A & C Black. doi:10.1093/ww/9780199540884.013.258560.(Subscription or UK public library membership required.)
  2. 1 2 Anon (2002). "EMBO Member: Anne Ridley". people.embo.org. Heidelberg: European Molecular Biology Organization.
  3. 1 2 3 4 5 6 7 Anon (2017). "Professor Anne Ridley FRS". London: royalsociety.org.
  4. 1 2 Anon (2016). "Meet the Professors: Anne Ridley". King's College London.
  5. Bristol, University of. "July: Anne Ridley - News - University of Bristol". www.bristol.ac.uk.
  6. 1 2 Anon (2016). "Professor Anne Ridley". London: King's College London. Archived from the original on 27 March 2016.
  7. 1 2 Anne Ridley publications from Europe PubMed Central
  8. Anne Ridley publications indexed by the Scopus bibliographic database. (subscription required)
  9. 1 2 Anon (2006). "Anne Ridley Profile" (PDF). ascb.org. Archived from the original (PDF) on 13 July 2007.
  10. Ridley, Anne Jacqueline (1989). Mechanisms of oncogene action and interaction in Schwann cells. london.ac.uk (PhD thesis). University of London. OCLC   940319396.
  11. Ridley, A. J.; Davis, J. B.; Stroobant, P.; Land, H. (1989). "Transforming growth factors-beta 1 and beta 2 are mitogens for rat Schwann cells". Journal of Cell Biology . 109 (6 Pt 2): 3419–3424. doi:10.1083/jcb.109.6.3419. ISSN   0021-9525. PMC   2115905 . PMID   2557356.
  12. Ridley, A J; Paterson, H F; Noble, M; Land, H (1988). "Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation". The EMBO Journal . 7 (6): 1635–1645. doi:10.1002/j.1460-2075.1988.tb02990.x. ISSN   0261-4189. PMC   457147 . PMID   3049071.
  13. Ridley, Anne J (2015). "Rho GTPase signalling in cell migration". Current Opinion in Cell Biology . 36: 103–112. doi:10.1016/j.ceb.2015.08.005. PMC   4728192 . PMID   26363959. Open Access logo PLoS transparent.svg
  14. Ridley, Anne Jacqueline (2016). "Anne Ridley: Networking with Rho GTPases". Trends in Cell Biology . 26 (7): 465–466. doi:10.1016/j.tcb.2016.04.005. ISSN   0962-8924. PMID   27166090.(subscription required)
  15. Heasman, Sarah J.; Ridley, Anne J. (2008). "Mammalian Rho GTPases: new insights into their functions from in vivo studies". Nature Reviews Molecular Cell Biology . 9 (9): 690–701. doi:10.1038/nrm2476. PMID   18719708. S2CID   16205866.(subscription required)
  16. Ridley, Anne J. (2006). "Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking". Trends in Cell Biology. 16 (10): 522–529. doi:10.1016/j.tcb.2006.08.006. ISSN   0962-8924. PMID   16949823.(subscription required)
  17. Cantelli, Gaia (2016). Transcriptional programs controlling actomyosin contractility in melanoma. ethos.bl.uk (PhD thesis). King's College London. EThOS   uk.bl.ethos.700781. Lock-green.svg
  18. Dwyer, Joseph (2015). Characterisation of the formin protein FHOD1 in striated muscle. ethos.bl.uk (PhD thesis). King's College London. OCLC   929654231. EThOS   uk.bl.ethos.677210. Lock-green.svg
  19. Philippeos, Christina (2014). Insulin signalling in endothelial cells. ethos.bl.uk (PhD thesis). King's College London. OCLC   918458935. EThOS   uk.bl.ethos.677057. Lock-green.svg
  20. "UK government grants awarded to Anne Ridley". rcuk.ac.uk. Swindon: Research Councils UK.
  21. Anne Ridley ORCID   0000-0001-8186-5708