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Medical condition
Antrectomy
a. Antrectomy is performed along the dashed lines, with the removal of stomach parts highlighted in gray. b. An end-to-end anastomosis is created between the remnant stomach (S) and duodenum (D).
The history of antrectomy traces back to the 19th century, starting with the first successful gastric resection in 1810. Since then, antrectomy has undergone a magnitude of changes, where development in the field continues to this day. Even though antrectomy paired with vagotomy and anastomosis is now the established gold standard, its side effects and clinical relevance remains a controversial subject. With advancements in alternative surgeries and other non-invasive treatments, antrectomy is less common nowadays.
Purpose
Generally, an antrectomy is performed to treat bleeding and blockage of the stomach.[2] This could be caused by a variety of gastric disorders, including:
Peptic ulcer disease, an ailment commonly corrected by antrectomy.
Peptic ulcer disease (PUD): The disease is characterized by ulcers developed either by impaired mucus protection or an excess of gastric acid production.[5] Antrectomy could either lead to the reduction of gastric acid levels or the removal of the peptic ulcer altogether. Antrectomy is rarely warranted in this case since PUD rarely recurs and is usually manageable via medications.[1]
Zollinger–Ellison syndrome: The condition features excessive gastric acid production.[6] Antrectomy removes gastrin-producing G-cells in the stomach antrum, in turn reducing gastric acid levels.
Gastric cancer: Antrectomy could remove gastric tumors developing in the antrum.[1]
Gastric antral vascular ectasia syndrome (GAVE): The disease is characterized by excessive bleeding in the stomach. By removing the bleeding site and reconnecting the upper stomach with the intestines, antrectomy controls chronic bleeding and ensures gastric continuity.[1]
Gastric outlet obstruction (GOO): It is a condition where the passage between the stomach and the duodenum is blocked. Removal of the blocked stomach parts by antrectomy could ensure continuity of the gastrointestinal system.[1]
The most common diagnostic tests for stomach disorders include endoscopy, double-contrast barium x-ray study of the upper GI tract, and the detection of H. pylori infection.[7]
Surgical procedure
A midline epigastric incision is first made from the xiphoid process of the sternum to the umbilicus.[8] The opening can be widened by extending the incision inferiorly.[8] When the abdominal organs are exposed, thorough exploration is undertaken to assess the extent of disease and, in the case of stomach cancer, to confirm resectability.[8]
Two surgical methods can then be used to perform antrectomy:[9]
The gastrocolic ligament of the greater omentum is incised at the middle of the greater curvature of the stomach, which opens the lesser sac.[9] The dissection for gastric ulcers can be done between the gastroepiploic vessels and the gastric wall.[9] In carcinoma, the greater omentum corresponding to the extent of the resection of the greater curvature must be removed at the same time.[9] The incision continues along the greater curvature towards the duodenum.[9] Near the pylorus of the stomach, the greater omentum becomes thick and divides into the front and back layer.[9] Dissection should be continued bluntly and the right gastroepiploic vessels running between the two layers are ligated.[9]
The Kocher manoeuver is used at a position above or just below the descending (second) part of the duodenum from a lateral direction.[9] The duodenum is mobilised to achieve a good general exposure, which facilitates the subsequent gastroduodenostomy.[9] The preparation of the free superior (first) part of the duodenum is then continued.[9] By stretching the stomach, the dissection proceeds along the greater curvature toward the left medial duodenal wall, then toward the back wall, and finally toward the lateral duodenal wall of the superior part as far as the beginning of the hepatoduodenal ligament.[9] This way, 3 to 5cm of the back wall of the duodenum can be exposed.[9]
The actual resection starts with the cutting of the duodenum between holding or guy sutures.[9] The duodenum is temporarily closed with a sponge; the resection borders of the stomach are then determined.[9]
A sewing instrument facilitates the final step of stomach removal.[9] The incision follows at an angle of 45 degrees to the lesser curvature.[9] The staple line can, but need not, be oversewn.[9] After removal of the distal portion (including the antrum and the pylorus) of the stomach, a clamp is fitted at right angles to the greater curvature.[9] The clamp is pushed far enough orally (towards the mouth) for the removal level to correspond in size to the duodenal lumen.[9] The remaining aboral (away from the mouth) end is cut off after stay sutures are placed at each cut edge.[9] The anastomosis should be performed without clamps.[9]
The end-to-end gastroduodenostomy is accomplished by anastomosing the duodenum to the end of the greater curvature.[9] For this purpose, the two cut surfaces are placed adjacent to each other and two corner stitches are placed, starting at the stomach through the seromuscular layers with tangential grasping of the mucosa.[9] At the duodenum, this stitch is done from inside to outside.[9] The corner suture at the lesser curvature is tied, whereas the suture on the opposite side is left open.[9] The back wall is reconstructed by interrupted back stitches.[9] These stitches start through all layers of the back wall at the cut edge of the lesser curvature from inside to outside and go through all layers of the posterior wall of the duodenum from outside to inside.[9] The suture is led back grasping only the mucosa, first of the duodenum and then of the stomach.[9] Knotting these sutures leads to an exact coaptation, especially at the level of the mucosa.[9] The front wall is best closed with one row of interrupted sutures through all layers with tangential stitches of the mucosa with the same technique as the corner stitches.[9] Special attention must be paid to the Jammerecke (angle of sorrow) on the lesser curvature.[9]
Finally, the anastomosis is checked for patency with the thumb and index finger.[9] The position of the stomach tube is also checked to ensure it crosses the anastomosis.[9] A double-lumen gastric tube is placed across the anastomosis for 2 to 3 days, allowing early enteral nutrition via the distal lumen.[9]
With end-to-side surgical anastomosis
In difficult duodenal ulcers, it can be impossible to preserve enough duodenal wall to be able to construct a tension-free anastomosis.[9] In this situation, it is safer to staple close the duodenum and reconstruct the intestinal passage by end-to-side anastomosis.[9] For this purpose, the stomach is removed as previously described; the dissected stomach lumen is then anastomosed onto the front wall of the duodenum.[9]
Usually, an oblique incision should be made on the duodenal front wall so that the incision level starts from oral–medial and goes to aboral–lateral.[9] The suturing technique is the same as for the end-to-side anastomosis.[9] In technically difficult duodenal stump closures, additional coverage of the stump with the back wall of the stomach can be obtained.[9]
Billroth II (BII) reconstruction method
Billroth II (BII) reconstruction method
Both the left gastric and left gastroepiploic artery are preserved in this method, although the resection is more extended.[9]
At the oral margin of the dissection line, usually covering two-thirds of the stomach, the resection is completed by transverse application of a linear stapler in a way that the complete stomach is divided between one stapler application.[9] The staple line can be oversewn.[9]
The first or second loop of the jejunum is then mobilised and placed tension-free and in a retrocolonic fashion opposite the greater curvature of the remaining stomach.[9] The loop should be long enough and should have a Braun jejunojejunostomy between the ascending and the descending loop.[9]
The last 4 to 5cm of the stapler line towards the greater curvature should be excised with the help of an electrocautery device in order to form a slim opening for the subsequent gastrojejunostomy.[9]Stay sutures are placed on both sides of the anastomosis.[9] The jejunum is incised with the electrocautery device opposite the mesentery.[9]
The gastrojejunostomy is performed by single interrupted sutures with resorbable suture material and, as the anastomosis cannot be turned, the back wall is sutured by interrupted mattress sutures and the front wall by extramucosal interrupted sutures.[9] Alternatively, continuous suturing with a monofilament resorbable thread on both sides of the anastomosis is possible.[9] Before finalisation of the front wall, a double-lumen gastric tube is placed distally to the anastomosis, allowing early enteral nutrition.[9] In order to prevent enterogastric (bile) reflux, the formation of a jejunojejunostomosis (Braun anastomosis), side-to-side, and 30cm aborally of the gastrojejunostomy is mandatory.[9] This anastomosis can be either hand-sewn (interrupted or continuous technique, resorbable suture material) or stapled.[9]
Supplementary operations
Supplementary operations can be applied alongside antrectomy to maximise its success and effectiveness. One commonly performed is vagotomy (the removal of the vagus nerve), since the vagus nerve also plays a key role in gastric juice regulation. While performed separately, vagotomy and antrectomy reduce stomach acid secretion by up to 60%.[10] Combining both practices could reduce stomach acid secretion by up to 80% through an additive effect.[10] In some cases, antrectomy can be used alongside laparoscopicsleeve gastrectomy to facilitate weight loss.[11] Yet, the clinical relevance of including antrectomy in this procedure remains to be seen.[11]
Outcome
The success rate of antrectomy is dependent on the rationale of the surgery. For example, antrectomies that are done to overcome peptic ulcer disease (PUD) have a 95% success rate, while the percentage is higher for gastric antral vascular ectasia syndrome (GAVE).[4] However, antrectomies that deal with gastric cancer or penetrative wounds are not as successful.[4] One possible explanation is that these symptoms are usually more severe and therefore harder to treat, no matter the kinds of surgery used.[4]
Nowadays, the mortality rates for antrectomy are typically low. The death rate of antrectomy for ulcer treatment is 1-2%, while it is 1-3% for gastric cancer.[4] Similarly, the chances of developing complications after surgery depend on the reason for the surgery and the type of complication in question. For example, antrectomy for peptic ulcers has a 1-5% chance for the condition to recur, a 12% chance of developing diarrhea, and a 30-35% chance of developing Dumping syndromes.[4]
History
Theodor Billroth, the first physician to execute a successful gastrectomy
The clinical basis of antrectomy was laid in the 19th century with the birth of its father - gastric resection. The first attempt at gastric resection was by German professor and surgeon Christian Michaelis, whose experiment on removing pylorus in animals to resolve gastric obstruction failed.[12] In 1810, his student Daniel Merrem successfully performed the resection of the distalstomach and reconnected the duodenum to the stomach in animal experiments.[12] The first clinical attempt of a gastric resection occurred in 1879 by French surgeon Jules-Émile Péan, who unsuccessfully carried out a pylo-rectomy for a cancer patient.[12] This was followed by the attempt of Polish surgeon Ludwik Rydygier, whose gastric resection also ended in the death of his patient.[12] It was not until 1881 was the first successful gastrectomy carried out by German physicianTheodor Billroth. Billroth first tested gastrectomy surgery on animals in an experiment known as ‘Billroth I gastrectomy’, which resulted in the long-term survival of two out of seven dogs.[12] This eventually led to the first successful gastric resection in a patient with stomach cancer, in which the duodenum was cut 1.5cm away from the tumor and reattached to the stomach with carbolized silk.[12] The practice was then quickly applied to Billroth’s clinics, with 19 successful operations out of 41 gastrectomies by 1890.[12]
Following the success of the first gastric resection, the birth of antrectomy is attributed to a better understanding of the gastrointestinal system in the early 20th century. Upon the discovery of gastrin by John S. Edkins in 1906, E. Klein published the first report combining vagotomy with gastrectomy to ease symptoms of excessive gastric juice secretion.[13] By 1946, American physicians Farmer and Smithwick performed the first vagotomy with hemigastrectomy (the removal of one-half of the stomach).[13] In the following year, Herrington of Vanderbilt University similarly combined vagotomy with the removal of the lower stomach to improve operational effectiveness, sparking the earliest resemblance to the antrectomy performed today.[13] During the same period, other variations of Billroth's gastrectomy such as concurrent gastrojejunal anastomosis were also transforming the landscape of gastrectomy, with the most notable contributions by surgeons Hofmeister, Polya, von Haberer, and Finsterer.[12] These variations influenced the way antrectomy is practiced, specifically the type of surgeries that antrectomy is paired with.
In the subsequent decades, antrectomy continued to evolve with advancements in surgical techniques. The 1950s marked the popularization of diagnostic and operational laparoscopy in hospitals and medical training.[14] This meant that antrectomy could be performed in a minimally invasive manner. However, complications such as diarrhea in antrectomy continue to be a problem, with a 1952 edition of The Lancet Review commenting, 'fashions in the treatment of peptic ulcer come and go, and the surgical problem remains unsolved.'[15] Hence the 1950s and 60s also marked the era of comparative studies of stomach surgery in an attempt of finding an effective method with the least side effects. Most notably, the 1968 Leads-York controlled trial published by The British Medical Journal found that the combination of vagotomy and gastrectomy is superior to other forms of surgery such as gastroenterostomy on the Visick grading (scoring system to quantify the symptomatic outcome of peptic ulcer surgery).[16]
The decades leading up to the present featured shifting applications of antrectomy. With the commercialization of acid-reducing medications such as antacids in the late 1970s, the incidence and prevalence of gastric ulcers fell, hence reducing the need for antrectomy. At the same time, British physician David Cowley became the first person to diagnose and treat pseudo-Zollinger-Ellison syndromes (stomach ulceration and excessive gastric acid production) using antrectomy and vagotomy.[17] In the subsequent decades, a better understanding of the Zollinger-Ellison syndrome led to antrectomy becoming one of the key treatment methods for the ailment.
Despite this, advent of newer non-invasive methods of resolving gastric disorders have made antrectomy less relevant nowadays. By 2003, antrectomy is no longer recognized as the first-line treatment for gastric antral vascular ectasia (watermelon stomach) and peptic ulcer disease.[4]
Benefits
Visual representation of stomach cancer, a condition that could be directly resolved by antrectomy
Antrectomy can reduce acid secretion in PUD and remove premalignant tissue to reduce gastric cancer odds.[1] This offers a permanent method that has a 95% success rate. It also alleviates pain, hemorrhage, and anemia from recurring stomachulcers. For localized cancer cases, antrectomy can eliminate early-stage cancer in the third (lower) portion of the stomach. Moreover, antrectomy is able to treat PUD and GOO by the removal of malignant tissues which controls early-stage gastric cancer while retaining sufficient portions of the stomach for adequate digestion and nutrition uptake. Furthermore, treating obesity with antrectomy is also becoming more common. Antrectomy is also the immediate and only approach to reconstructing organs from injuries such as stabbing in the lower portion of the stomach.
Risks and complications
Antrectomy results in the removal of parts of the stomach, reducing the functions of a normal stomach. Around 30% of patients develop Dumping syndrome, a condition where food entering the stomach enters the intestines prematurely due to a partially removed stomach not maximizing its digestive function. It causes heartburn, nausea, fatigue, and vomiting after meals.[4] In addition, other side effects include dysphagia, which is when digestive juices in the duodenum flow upward to the esophagus, thus esophageal lining is irritated. Diarrhea is common, especially in patients who had vagotomy in addition to an antrectomy because the damage of nerves to the liver and gallbladder causes excess bile salt release.
Due to a decrease in gastric function, patients have to adjust to a diet composed of high protein and low carbohydrates.[4] They must take more liquids when eating and have small and frequent meals. The decreased gastric function also leads to malabsorption and malnutrition, especially for iron, folate, and calcium because acid is important for assimilating these substances.[18] Therefore, weight loss due to decreased food intake and malnutrition is common in patients in recovery, especially in elderly patients. Additionally, Bezoar development obstruction of the digestive tract is also seen in postoperative patients because the fiber and more solid food are not fully digested by the shrunk stomach.[4]
Other than side effects, the success of antrectomy in treating the target condition is also debatable. Antrectomy removing a part of the stomach does not treat later-stage cancer.[19] For PUD patients, antrectomy alone could still cause the recurrence of gastric ulcers,[18] even if paired with a vagotomy. Leakage from anastomosis of the resected stomach and small intestines can also occur in some patients
Alternatives and medication
Antrectomy is an invasive surgery that is only performed when patients experience bleeding, perforation, obstruction, and malignancy. Treatment alternatives are based on their diagnosis.
Antrectomy is often not considered a first-line treatment for PUD due to the high success rate of medication and antibiotics.[21] Suitable candidates are those who failed to recover from treatment with over-the-counter NSAID and have severe damage to the stomach lining.[22]
“Triple therapy” is a combination of antibiotics to rid bacterium, protect the stomach lining and reduce stomach acid production.[4] The drug types include:
Sucralfate, a compound of sucrose, and aluminum that coats ulcers allowing eroded tissues to recover.
Antibiotics to treat H. pylori if it is detected, such as Bismuth subsalicylate which can also protect the stomach lining
NSAIDS (Prostaglandins) to reduce pain and protect the stomach lining and reduce acid secretion. Misoprostol is the most effective choice
For cancer, chemotherapy is the most common alternative to antrectomy. Antrectomy is suitable for early-stage gastric cancer as complete removal can stop cancer spread. With advancements in endoscopic surgeries, endoscopic mucosal resection (EMR) is a non-invasive choice that is safer than antrectomy for small tumor removals in the distal portion of the stomach.[19] For late-stage cancer where malignancy is spread to other organs, chemotherapy is preferred as surgery cannot eliminate cancer.[4] Cancer patients’ condition is also considered when making surgical decisions.
Gastric outlet obstruction (GOO)
Other surgeries can manage GOO. Surgical approaches are decided based on the patient’s condition and the development of the condition. Enteral stents are used to expand the obstruction of the pylorus. Medication is used to protect the stomach lining.
In the past, 89-90% of ulcer-related GOO patients required surgery.[24] As the development of endoscopic procedures advances, recent reports suggest that endoscopic balloon dilation is an effective treatment option for GOO and PUD.
For Type I, II, and III ulcers, robot-assisted gastric antrectomy and vagotomy are gaining popularity. This method reduces blood loss and length of stay but the operation duration is longer.[21] It carries out exact dissections in a scarred stomach and duodenum and offers magnification and smooth articulation of instruments.[25]
As robotic antrectomy is not popularized in most hospitals, intracorporeal antrectomy and anastomosis are the most common for tumor removal and curing complicated PUD as it is comparatively less invasive and minimizes blood loss. The first case of single-incision laparoscopic antrectomy for type I gastric neuroendocrine tumor was reported in 2021.[26]
In recent years, antrectomy has been used to control obesity.[27] There are debates on the safety and efficiency of this procedure regarding the distance from the pylorus of which the resection takes place. Trials and reviews have been done on exploring the postoperative effects, nausea and vomiting, and chance of leakage from anastomosis when antrectomy is done 2cm or less from the pylorus.[28] Developments aim to reduce the stomach volume in obese patients while retaining digestive function and ensuring safety.
Related Research Articles
Peptic ulcer disease is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus. An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer. The most common symptoms of a duodenal ulcer are waking at night with upper abdominal pain, and upper abdominal pain that improves with eating. With a gastric ulcer, the pain may worsen with eating. The pain is often described as a burning or dull ache. Other symptoms include belching, vomiting, weight loss, or poor appetite. About a third of older people with peptic ulcers have no symptoms. Complications may include bleeding, perforation, and blockage of the stomach. Bleeding occurs in as many as 15% of cases.
Gastric bypass surgery refers to a technique in which the stomach is divided into a small upper pouch and a much larger lower "remnant" pouch, where the small intestine is rearranged to connect to both. Surgeons have developed several different ways to reconnect the intestine, thus leading to several different gastric bypass procedures (GBP). Any GBP leads to a marked reduction in the functional volume of the stomach, accompanied by an altered physiological and physical response to food.
A gastrectomy is a partial or total surgical removal of the stomach.
A pancreaticoduodenectomy, also known as a Whipple procedure, is a major surgical operation most often performed to remove cancerous tumours from the head of the pancreas. It is also used for the treatment of pancreatic or duodenal trauma, or chronic pancreatitis. Due to the shared blood supply of organs in the proximal gastrointestinal system, surgical removal of the head of the pancreas also necessitates removal of the duodenum, proximal jejunum, gallbladder, and, occasionally, part of the stomach.
A gastroenterostomy is the surgical creation of a connection between the stomach and the jejunum. The operation can sometimes be performed at the same time as a partial gastrectomy. Gastroenterostomy was in the past typically performed to treat peptic ulcers, but today it is usually carried out to enable food to pass directly to the middle section of the small intestine when it is necessary to bypass the first section because of duodenal damage. The procedure is still being used to treat gastroparesis that is refractory to other treatments, but it is now rarely used to treat peptic ulcers because most cases thereof are bacterial in nature and there are many new drugs available to treat the gastric reflux often experienced with peptic ulcer disease. Reported cure rates for H. pylori infection range from 70% to 90% after antibiotic treatment.
Duodenal cancer is a cancer in the first section of the small intestine known as the duodenum. Cancer of the duodenum is relatively rare compared to stomach cancer and colorectal cancer. Its histology is usually adenocarcinoma.
Sleeve gastrectomy or vertical sleeve gastrectomy, is a surgical weight-loss procedure, typically performed laparoscopically, in which approximately 75 - 85% of the stomach is removed, along the greater curvature, which leaves a cylindrical, or "sleeve"-shaped stomach the size of a banana. Weight loss is affected not only through the reduction of the organ's size, but by the removal of the portion of it that produces ghrelin, the hormone that stimulates appetite. Patients can lose 50-70 percent of excess weight over the course of the two years that follow the surgery. The procedure is irreversible, though in some uncommon cases, patients can regain the lost weight, via resumption of poor dietary habits, or dilation of the stomach over time, which can require gastric sleeve revision surgery to either repair the sleeve or convert it to another type of weight loss method that may produce better results, such as a gastric bypass or duodenal switch.
A vagotomy is a surgical procedure that involves removing part of the vagus nerve. It is performed in the abdomen.
A bowel resection or enterectomy is a surgical procedure in which a part of an intestine (bowel) is removed, from either the small intestine or large intestine. Often the word enterectomy is reserved for the sense of small bowel resection, in distinction from colectomy, which covers the sense of large bowel resection. Bowel resection may be performed to treat gastrointestinal cancer, bowel ischemia, necrosis, or obstruction due to scar tissue, volvulus, and hernias. Some patients require ileostomy or colostomy after this procedure as alternative means of excretion. Complications of the procedure may include anastomotic leak or dehiscence, hernias, or adhesions causing partial or complete bowel obstruction. Depending on which part and how much of the intestines are removed, there may be digestive and metabolic challenges afterward, such as short bowel syndrome.
Gastric outlet obstruction (GOO) is a medical condition where there is an obstruction at the level of the pylorus, which is the outlet of the stomach. Individuals with gastric outlet obstruction will often have recurrent vomiting of food that has accumulated in the stomach, but which cannot pass into the small intestine due to the obstruction. The stomach often dilates to accommodate food intake and secretions. Causes of gastric outlet obstruction include both benign causes, as well as malignant causes, such as gastric cancer.
Billroth II, more formally Billroth's operation II, is an operation in which a partial gastrectomy is performed and the cut end of the stomach is closed. The greater curvature of the stomach is then connected to the first part of the jejunum in end-to-side anastomosis. The Billroth II always follows resection of the lower part of the stomach (antrum). The surgical procedure is called a partial gastrectomy and gastrojejunostomy. The Billroth II is often indicated in refractory peptic ulcer disease and gastric adenocarcinoma.
In general surgery, a Roux-en-Y anastomosis, or Roux-en-Y, is an end-to-side surgical anastomosis of bowel used to reconstruct the gastrointestinal tract. Typically, it is between stomach and small bowel that is distal from the cut end.
Stump blow-out, or duodenal blow-out, is the leakage of the blind end of the duodenum. It occurs as a complication of Billroth II gastrectomy, usually on the fourth or fifth day after surgery. It is due to improper closure of duodenal stump, especially when the duodenum is inflamed and oedematous. It can also occur because of afferent loop block, local pancreatitis and distal obstruction. The patient who was previously convalescing satisfactorily may suddenly present with severe abdominal pain, fever and shock-like state. Jaundice may develop within 48 hours owing to the absorption of bile from peritoneal cavity. If the abdomen is drained, bile-stained fluid may be seen emerging at the drain site. Intravenous fluids should be started and adequate surgical drainage should be provided. Surgery is indicated when there is peritonitis, unresponsive fistula or distal obstruction. Once the life-threatening phase is over, the priority should be to give adequate nutrition. Surgical loop connection relieves the obstruction distally.
SADI-S is a bariatric surgical technique to address metabolic disorders and to lose weight. It is a variation on the Duodenal Switch surgery, incorporating a vertical sleeve gastrectomy with a gastric bypass technique.
Pyloroplasty is a surgery performed to widen the opening at the lower part of the stomach, also known as the pylorus. When the pylorus thickens, it becomes difficult for food to pass through. The surgery is performed to widen the band of muscle known as the pyloric sphincter, a ring of smooth, muscular fibers that surrounds the pylorus and helps to regulate digestion and prevent reflux. The widening of the pyloric sphincter enables the contents of the stomach to pass into the first part of the small intestine known as the duodenum.
Stomach Intestinal Pylorus-Sparing (SIPS) surgery is a type of weight-loss surgery. It was developed in 2013 by two U.S. surgeons, Daniel Cottam from Utah and Mitchell S. Roslin from New York.
Retained antrum syndrome or retained gastric antrum syndrome is one of the rare postgastrectomy syndromes. It happens after Billroth II surgery and the mechanism involved is the inadequate removal of the distal antrum and pylorus during resection of the antrum and gastrojejunostomy.
Acid peptic diseases, such as peptic ulcers, Zollinger-Ellison syndrome, and gastroesophageal reflux disease, are caused by distinct but overlapping pathogenic mechanisms involving acid effects on mucosal defense. Acid reflux damages the esophageal mucosa and may also cause laryngeal tissue injury, leading to the development of pulmonary symptoms.
Choledochoduodenostomy (CDD) is a surgical procedure to create an anastomosis, a surgical connection, between the common bile duct (CBD) and an alternative portion of the duodenum. In healthy individuals, the CBD meets the pancreatic duct at the ampulla of Vater, which drains via the major duodenal papilla to the second part of duodenum. In cases of benign conditions such as narrowing of the distal CBD or recurrent CBD stones, performing a CDD provides the diseased patient with CBD drainage and decompression. A side-to-side anastomosis is usually performed.
Stomach reduction surgery, also known as bariatric surgery, is a medical procedure aimed at facilitating weight loss by reducing the size of the stomach, thereby limiting food intake and promoting satiety with smaller portions. It is frequently used for cases where traditional weight loss approaches, consisting of diet and physical activity, have proven insufficient, or when obesity already significantly affects well-being and general health.
References
1 2 3 4 5 6 7 Hiam, Deirdre (2020). The Gale Encyclopedia of Surgery and Medical Tests (4thed.). America: Gale. p.126. ISBN978-0028666518.
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