| branched-chain-2-oxoacid decarboxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.1.1.72 | ||||||||
| CAS no. | 63653-19-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme branched-chain-2-oxoacid decarboxylase (EC 4.1.1.72) catalyzes the chemical reaction
- (3S)-3-methyl-2-oxopentanoate 2-methylbutanal + CO2
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (3S)-3-methyl-2-oxopentanoate carboxy-lyase (2-methylbutanal-forming). Other names in common use include branched-chain oxo acid decarboxylase, branched-chain alpha-keto acid decarboxylase, branched-chain keto acid decarboxylase, BCKA, and (3S)-3-methyl-2-oxopentanoate carboxy-lyase.
