Names | |
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IUPAC name N2-Butyl-N1-(2-chloro-6-methylphenyl)glycinamide | |
Systematic IUPAC name 2-(Butylamino)-N-(2-chloro-6-methylphenyl)acetamide | |
Identifiers | |
3D model (JSmol) | |
ChEBI | |
ChEMBL | |
ChemSpider | |
PubChem CID | |
UNII | |
CompTox Dashboard (EPA) | |
| |
| |
Properties | |
C13H19ClN2O | |
Molar mass | 254.75576 |
Pharmacology | |
N01BB05 ( WHO ) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
Butanilicaine is a local anesthetic. It is also known by the name Hostacaine.
Amide formation by the combination of 2-chloro-6-methylaniline (1) and chloroacetyl chloride (2) gives the intermediate (3), which is used to alkylate N-butylamine (4) to yield butanilicaine. [1] [2] [3]
In probability theory and statistics, the binomial distribution with parameters n and p is the discrete probability distribution of the number of successes in a sequence of n independent experiments, each asking a yes–no question, and each with its own Boolean-valued outcome: success or failure. A single success/failure experiment is also called a Bernoulli trial or Bernoulli experiment, and a sequence of outcomes is called a Bernoulli process; for a single trial, i.e., n = 1, the binomial distribution is a Bernoulli distribution. The binomial distribution is the basis for the popular binomial test of statistical significance.
The number e is a mathematical constant approximately equal to 2.71828 that can be characterized in many ways. It is the base of the natural logarithm function. It is the limit of as n tends to infinity, an expression that arises in the computation of compound interest. It is the value at 1 of the (natural) exponential function, commonly denoted It is also the sum of the infinite series There are various other characterizations; see § Definitions and § Representations.
In mathematics, the Fibonacci sequence is a sequence in which each number is the sum of the two preceding ones. Numbers that are part of the Fibonacci sequence are known as Fibonacci numbers, commonly denoted Fn . The sequence commonly starts from 0 and 1, although some authors start the sequence from 1 and 1 or sometimes from 1 and 2. Starting from 0 and 1, the sequence begins
In mathematics, two quantities are in the golden ratio if their ratio is the same as the ratio of their sum to the larger of the two quantities. Expressed algebraically, for quantities and with , is in a golden ratio to if
In probability theory and statistics, a normal distribution or Gaussian distribution is a type of continuous probability distribution for a real-valued random variable. The general form of its probability density function is The parameter is the mean or expectation of the distribution, while the parameter is the variance. The standard deviation of the distribution is . A random variable with a Gaussian distribution is said to be normally distributed, and is called a normal deviate.
The number π is a mathematical constant that is the ratio of a circle's circumference to its diameter, approximately equal to 3.14159. The number π appears in many formulae across mathematics and physics. It is an irrational number, meaning that it cannot be expressed exactly as a ratio of two integers, although fractions such as are commonly used to approximate it. Consequently, its decimal representation never ends, nor enters a permanently repeating pattern. It is a transcendental number, meaning that it cannot be a solution of an equation involving only finite sums, products, powers, and integers. The transcendence of π implies that it is impossible to solve the ancient challenge of squaring the circle with a compass and straightedge. The decimal digits of π appear to be randomly distributed, but no proof of this conjecture has been found.
A prime number is a natural number greater than 1 that is not a product of two smaller natural numbers. A natural number greater than 1 that is not prime is called a composite number. For example, 5 is prime because the only ways of writing it as a product, 1 × 5 or 5 × 1, involve 5 itself. However, 4 is composite because it is a product (2 × 2) in which both numbers are smaller than 4. Primes are central in number theory because of the fundamental theorem of arithmetic: every natural number greater than 1 is either a prime itself or can be factorized as a product of primes that is unique up to their order.
In optics, the refractive index of an optical medium is a dimensionless number that gives the indication of the light bending ability of that medium.
In statistics, the standard deviation is a measure of the amount of variation of a random variable expected about its mean. A low standard deviation indicates that the values tend to be close to the mean of the set, while a high standard deviation indicates that the values are spread out over a wider range. The standard deviation is commonly used in the determination of what constitutes an outlier and what does not.
In mathematics, the Taylor series or Taylor expansion of a function is an infinite sum of terms that are expressed in terms of the function's derivatives at a single point. For most common functions, the function and the sum of its Taylor series are equal near this point. Taylor series are named after Brook Taylor, who introduced them in 1715. A Taylor series is also called a Maclaurin series when 0 is the point where the derivatives are considered, after Colin Maclaurin, who made extensive use of this special case of Taylor series in the 18th century.
In probability theory and statistics, variance is the expected value of the squared deviation from the mean of a random variable. The standard deviation (SD) is obtained as the square root of the variance. Variance is a measure of dispersion, meaning it is a measure of how far a set of numbers is spread out from their average value. It is the second central moment of a distribution, and the covariance of the random variable with itself, and it is often represented by , , , , or .
The weighted arithmetic mean is similar to an ordinary arithmetic mean, except that instead of each of the data points contributing equally to the final average, some data points contribute more than others. The notion of weighted mean plays a role in descriptive statistics and also occurs in a more general form in several other areas of mathematics.
In probability theory, the central limit theorem (CLT) states that, under appropriate conditions, the distribution of a normalized version of the sample mean converges to a standard normal distribution. This holds even if the original variables themselves are not normally distributed. There are several versions of the CLT, each applying in the context of different conditions.
2 (two) is a number, numeral and digit. It is the natural number following 1 and preceding 3. It is the smallest and only even prime number.
Radioactive decay is the process by which an unstable atomic nucleus loses energy by radiation. A material containing unstable nuclei is considered radioactive. Three of the most common types of decay are alpha, beta, and gamma decay. The weak force is the mechanism that is responsible for beta decay, while the other two are governed by the electromagnetism and nuclear force.
10 (ten) is the even natural number following 9 and preceding 11. Ten is the base of the decimal numeral system, the most common system of denoting numbers in both spoken and written language.
A round-robin tournament or all-play-all tournament is a competition format in which each contestant meets every other participant, usually in turn. A round-robin contrasts with an elimination tournament, wherein participants are eliminated after a certain number of wins or losses.
5 (five) is a number, numeral and digit. It is the natural number, and cardinal number, following 4 and preceding 6, and is a prime number.
In mathematics, a rational number is a number that can be expressed as the quotient or fraction of two integers, a numerator p and a non-zero denominator q. For example, is a rational number, as is every integer. The set of all rational numbers, also referred to as "the rationals", the field of rationals or the field of rational numbers is usually denoted by boldface Q, or blackboard bold
In probability theory and statistics, the Poisson distribution is a discrete probability distribution that expresses the probability of a given number of events occurring in a fixed interval of time if these events occur with a known constant mean rate and independently of the time since the last event. It can also be used for the number of events in other types of intervals than time, and in dimension greater than 1.