Gentamicin 2'-N-acetyltransferase

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gentamicin 2'-N-acetyltransferase
Identifiers
EC no. 2.3.1.59
CAS no. 50864-40-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, a gentamicin 2'-N-acetyltransferase (EC 2.3.1.59) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + gentamicin C1a CoA + N2'-acetylgentamicin C1a

Thus, the two substrates of this enzyme are acetyl-CoA and gentamicin C1a, whereas its two products are CoA and N2'-acetyl gentamicin C1a.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:gentamicin-C1a N2'-acetyltransferase. Other names in common use include gentamicin acetyltransferase II, gentamicin 2'-N-acetyltransferase, and acetyl-CoA:gentamicin-C1a N2'-acetyltransferase.

References