| Title | Released | Developer | Publisher |
|---|
| I Have No Mouth, and I Must Scream | 1995 | The Dreamers Guild | Cyberdreams |
| I of the Dragon | 2004 | Primal Software | Strategy First |
| I Spy Spooky Mansion | 2005 | Scholastic | Scholastic |
| I Wanna Be the Guy | 2007 | Michael "Kayin" O'Reilly | |
| I'm O.K – A Murder Simulator | 2005 | Thompsonsoft | Thompsonsoft |
| I-Ninja | 2003 | Argonaut Games | Namco, Sony Computer Entertainment, Zoo Digital Publishing |
| I-War | 1997 | Particle Systems | Infogrames |
| I.G.I.-2: Covert Strike | 2003 | Innerloop Studios | Codemasters |
| Ice & Fire | 1995 | AnimaTek | GT Interactive |
| Iced! | 2008 | Breakthrough | Breakthrough |
| Icewind Dale | 2000 | Black Isle Studios | Interplay Entertainment |
| Icewind Dale II | 2002 | Black Isle Studios | Interplay Entertainment |
| Icewind Dale: Heart of Winter | 2001 | Black Isle Studios | Interplay Entertainment |
| Ignition | 1995 | Unique Development Studios | Virgin Interactive |
| IL-2 Sturmovik | 2001 | 1C:Maddox Games | 1C, Ubisoft |
| IL-2 Sturmovik: Forgotten Battles | 2003 | 1C:Maddox Games | 1C, Ubisoft |
| Immaterial and Missing Power | 2004 | Twilight Frontier, Team Shanghai Alice | Twilight Frontier, Team Shanghai Alice |
| Immortal Cities: Children of the Nile | 2004 | Tilted Mill Entertainment | Myelin Media, SEGA |
| Imogen | 2003 | Ovine by Design | Ovine by Design |
| Imperialism | 1997 | Frog City Software | Strategic Simulations, Inc. |
| Imperialism II: Age of Exploration | 1999 | Frog City Software | Strategic Simulations, Inc. |
| Imperishable Night | 2004 | Team Shanghai Alice | Team Shanghai Alice |
| Imperium Galactica II: Alliances | 2000 | Digital Reality | GT Interactive |
| Imperialism | 2008 | Haemimont Games | Kalypso Media, SouthPeak Games |
| Imperivm: Great Battles of Rome | 2005 | Haemimont Games | FX Interactive |
| Impossible Creatures | 2003 | Relic Entertainment | Microsoft Game Studios |
| Impossible Spell Card | 2014 | Team Shanghai Alice | Team Shanghai Alice |
| Impressionists | 1997 | Index+ | Index+ |
| In Cold Blood | 2000 | Revolution Software | Ubisoft, DreamCatcher Games |
| In Memoriam | 2003 | Lexis Numerique | Ubisoft, The Adventure Company |
| In the Groove | 2004 | Roxor Games | Roxor Games, RedOctane |
| In the Hunt | 1997 | Kokopeli | Kokopeli |
| Incoming | 1998 | Rage Software | Interplay Entertainment, Imagineer |
| Incoming Forces | 2002 | Rage Software | Hip Interactive |
| The Incredible Hulk | 2008 | Edge of Reality | Sega |
| The Incredible Machine 2 | 1995 | Dynamix | Sierra On-Line |
| The Incredibles | 2004 | Heavy Iron Studios | THQ, D3, Capcom |
| The Incredibles: Rise of the Underminer | 2005 | Yuke's, Pacific Coast Power & Light | THQ, Capcom |
| Incubation: Time Is Running Out | 1997 | Blue Byte | Blue Byte |
| Independence Day | 1997 | Radical Entertainment | Fox Interactive |
| Independence War 2: Edge of Chaos | 2001 | Particle Systems | Infogrames |
| Indiana Jones and the Emperor's Tomb | 2003 | The Collective | LucasArts |
| Indiana Jones and the Infernal Machine | 1999 | LucasArts | LucasArts, THQ |
| Indie Pogo | 2018 | Lowe Bros. Studios | Lowe Bros. Studios |
| Industry Giant | 1998 | JoWood Productions | Interactive Magic |
| Industry Giant II | 2002 | JoWood Productions | JoWood Productions |
| IndustryMasters | 2007 | Thomas Lehnert | Tycoon Sistemas Ltda |
| IndyCar Series | 2003 | Codemasters | Codemasters |
| Infantry | 1999 | Harmless Games LLC | Sony Online Entertainment |
| Infernal | 2007 | Metropolis Software | Playlogic International |
| Infinity Online | 2006 | Windysoft | game & game |
| Inherit the Earth | 2003 | The Dreamers Guild | Wyrmkeep Entertainment |
| InkBall | 2004 | Microsoft | Microsoft |
| Innova Disc Golf | 2000 | Sundial Interactive | WizardWorks |
| Inquisition | 2003 | Wanadoo Edition | Wanadoo Edition |
| Insane | 2000 | Invictus Games | Codemasters |
| Insaniquarium | 2004 | Flying Bear Entertainment | PopCap Games |
| Insecticide | 2008 | Crackpot Entertainment, Creat Studios, Inc. | Gamecock Media Group |
| Insurgency: Modern Infantry Combat | 2007 | Insurgency Team | Valve |
| Intellivision Lives! | 1998 | Intellivision Productions | Intellivision Productions |
| International Cricket Captain | 1998 | Empire Interactive | Empire Interactive |
| International Rally Championship | 1997 | Magnetic Fields | Interplay Entertainment, THQ, Europress |
| International Superstar Soccer 3 | 2003 | KCEO | Konami |
| Interpol: The Trail of Dr. Chaos | 2007 | TikGames | Sierra Online |
| Interstate '76 | 1997 | Activision | Activision |
| Interstate '82 | 1999 | Activision | Activision |
| Iron Grip: Warlord | 2008 | Isotx | Isotx |
| Iron Lung | 2022 | David Szymanski | David Szymanski, Dread XP |
| Iron Man | 2008 | Artificial Mind and Movement | Sega |
| Iron Storm | 2002 | 4X Studio, Kylotonn | Dreamcatcher Interactive, Wanadoo Edition |
| Iron Warriors: T-72 Tank Commander | 2004 | IDDK/Crazy House | Battlefront.com |
| Ironclads: American Civil War | 2008 | Totem Games | Totem Games |
| Island Xtreme Stunts | 2002 | Silicon Dreams Studio | Lego Software |
| Istaria: Chronicles of the Gifted | 2003 | Artifact Entertainment | Artifact Entertainment, Virtrium LLC, Tulga Games, LLC, EI Interactive |
| The Italian Job | 2001 | Pixelogic | SCi, Global Star Software |