Pride Chigwedere

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Pride Chigwedere
Dr Pride Chigwedere.jpg
Born (1974-08-01) August 1, 1974 (age 49)
Nationality Flag of Zimbabwe.svg Zimbabwe
Education Harvard University (PhD)
University of Zimbabwe (MB ChB)
Known forShowing that about 300 000 untimely deaths occurred in South Africa because of untreated HIV/AIDS [1]
Scientific career
Fields HIV, Global health

Pride Chigwedere (born 1 August 1974), a Zimbabwean national, is a Harvard trained physician-scientist working in global health. He is most notable for leading a team of Harvard researchers who demonstrated that South African President Thabo Mbeki's AIDS policies led to more than 300 000 deaths. [2] [3] While South Africa's policies were condemned by many, Chigwedere's contribution was in developing and applying methods to quantify the impact of the policies thus demonstrating the calamitous consequences of AIDS denialism. Generalized, he developed an approach for evaluating public health practice and highlighted the need to develop a framework for accountability in public health. Drawing from the analogy with medicine, he has proposed the concept of public health malpractice to capture negligence that causes harm as a useful first step towards accountability in public health. [4] A response to Chigwedere's work by AIDS denialists led by Peter Duesberg was initially published by the non-peer-reviewed journal Medical Hypotheses followed by a retraction because of poor quality of data, undeclared conflicts of interest, and potential effects on global health. [5] [6]

Contents

Career and awards

Chigwedere worked as a physician in Zimbabwe, a viral immunologist and health policy analyst at the Harvard AIDS Initiative, and a management consultant at McKinsey & Company. He then joined UNAIDS as Coordinator for Universal Access for 21 countries in Eastern and Southern Africa, before taking the role of Senior Advisor to the African Union where he counseled the African Union and its Organs AU Commission, Pan African Parliament, NEPAD, African Commission on Human and Peoples' Rights etc.), and Regional Economic Communities, on AIDS and Health, working closely with and strengthening continental mechanisms such as AIDS Watch Africa, the African Peer Review Mechanism, statutory AU Forums (Heads of States Summits, Conference of African Ministers of Health etc.), and the Organisation of African First Ladies against HIV/AIDS (OAFLA). His current work as Senior Policy and Strategy Advisor for UNAIDS China attempts to leverage the political, financial and technological power of China for AIDS and broader global health, advising both China and Africa on how to strengthen partnerships for health including on pharmaceuticals, disease surveillance and response, and strengthening health systems.[ citation needed ]

Chigwedere's research is published in peer reviewed journals including the Journal of Virology, Human Immunology, AIDS Research and Human Retroviruses, and JAIDS , and he served as editorial advisor for the British Medical Journal special theme issue on Africa. [7] His work has been the subject of front-page articles in The New York Times , the International Herald Tribune , and The Times (South Africa), was featured on BBC, PBS and CNN , was commented on by leaders such as President Bill Clinton, and is the basis of a documentary 'The Price of Denial'. [8] [9] [10] [11] [12] Chigwedere has been interviewed on CNN , has archived presentations on ReachMD Radio and the WGBH-TV Forum Network, a service of PBS and NPR , and served as a health columnist for the Daily News , Zimbabwe, and his opinions have appeared on HBO television. [13] [14] [15] As teaching fellow and instructor, he taught classes at the Harvard College, Harvard Medical School, Harvard School of Public Health, and the Harvard Graduate School of Arts and Sciences, and has presented lectures and participated on high level panels including the Africa Now! Leadership Summit at the American Academy of Arts and Sciences, the John F. Kennedy Forum at the Institute of Politics, the Africa Business Conference at the Harvard Business School, the MIT Sloan School of Management, the Salem Human Rights Award, the Academia Sinica in Taiwan, the U.S. Africa Foreign Policy Conference, and the Zimbabwe Music Festival. [16] [17] [18] [19]

Dr Pride Chigwedere addressing a conference Pride Chigwedere.jpg
Dr Pride Chigwedere addressing a conference

In 2006, Chigwedere delivered the Lowell Lecture at the Boston Museum of Science, [20] and he was the keynote speaker at the 2006 International Conference on AIDS Orphans and Vulnerable Children where he was honored by the Boston City Council for his efforts in fighting the AIDS epidemic in Africa. [21]

In 2011, Chigwedere was honoured as one of Ten Outstanding Young Zimbabweans by Junior Chamber International, for his contributions to medical science and research. [22]

In 2015, Chigwedere was awarded the Harvard Chan Alumni's Emerging Public Health Leader Award for his work "at the center of the AIDS Response" in Africa. [23]

In 2016, Chigwedere was Zimbabwe's candidate for the position of the African Union Commissioner for Social Affairs 2017 to 2020. [24]

Education

Chigwedere earned a doctorate in immunology and infectious diseases with a second major in ethics of public health practice and an interdisciplinary certificate in the epidemiology of infectious diseases at the Harvard School of Public Health where he was one of three finalists for the Albert Schweitzer Award, the school's highest honor to graduating students. [25] He conducted post-doctoral work at the Harvard AIDS Initiative supervised by renowned retrovirologist Max Essex who is especially known for being first to provide the serological evidence that AIDS is caused by a retrovirus in 1983. He was the recipient of the Oak Foundation Award [26] and Forgaty Fellowship [27] for thesis and research support, was founding member and served as president of the Africa Health Forum, [28] and student representative for immunology and infectious diseases. During the studies at Harvard, Chigwedere took time as a visiting fellow to the McGill University AIDS Center and the Lady Davies Institute for Medical Research, Montreal, where he worked with Mark Wainberg, Chair of the 2006 International AIDS Conference and co-discoverer of the AIDS drug Lamivudine, and he completed certifications at the Foundation for Advanced Education in the Sciences at the National Institutes of Health, and the Pennsylvania State University Biotechnology Program.

Before that, Chigwedere had graduated from the University of Zimbabwe Medical School [29] where he received the Harry Wolfson Medals and Ethel Barrow Prizes for excellence in Biochemistry and Physiology, the Malvern Trust Scholarship for best preclinical Medicine results, the Wellcome Bursary for academic achievement and leadership, the Reuters / Tropical Health and Education Trust Prize for the best research project in Zimbabwe in the International Medical Students Competition, and the Solrarie - Grossberg Scholarship for Outstanding Overall Academic Achievement in the Doctor of Medicine degree. He served as the Secretary General of the Zimbabwe Medical Students Association, the Medical School Representative for the University Interfaculty Games, played soccer in the Socrates team, and was a demonstrator in Physiology and Anatomy to medical and pharmacy students. He then worked as a Resident Medical Officer at Harare Central Hospital and the Parirenyatwa Group of Hospitals where he did rotations in general and neurosurgery, internal medicine, obstetrics and pediatrics. During that time, he served as the Press and Publicity Secretary of the Hospital Doctors Association and wrote opinion editorials in the Zimbabwe Standard and the Zimbabwe Mirror newspapers.

Related Research Articles

The Duesberg hypothesis is the claim that AIDS is not caused by HIV, but instead that AIDS is caused by noninfectious factors such as recreational and pharmaceutical drug use and that HIV is merely a harmless passenger virus. The hypothesis was popularized by Peter Duesberg, a professor of biology at University of California, Berkeley, from whom the hypothesis gets its name. The scientific consensus is that the Duesberg hypothesis is incorrect and that HIV is the cause of AIDS. The most prominent supporters of the hypothesis are Duesberg himself, biochemist and vitamin proponent David Rasnick, and journalist Celia Farber. The scientific community generally contends that Duesberg's arguments in favor of the hypothesis are the result of cherry-picking predominantly outdated scientific data and selectively ignoring evidence that demonstrates HIV's role in causing AIDS.

<span class="mw-page-title-main">Peter Duesberg</span> German-American molecular biologist (born 1936)

Peter H. Duesberg is a German-American molecular biologist and a professor of molecular and cell biology at the University of California, Berkeley. He is known for his early research into the genetic aspects of cancer. He is a proponent of AIDS denialism, the claim that HIV does not cause AIDS.

<span class="mw-page-title-main">Thabo Mbeki</span> President of South Africa from 1999 to 2008

Thabo Mvuyelwa Mbeki is a South African politician who served as the second president of South Africa from 14 June 1999 to 24 September 2008, when he resigned at the request of his party, the African National Congress (ANC). Before that, he was deputy president under Nelson Mandela from 1994 to 1999.

<span class="mw-page-title-main">HIV/AIDS denialism</span> False belief that HIV does not cause AIDS

HIV/AIDS denialism is the belief, despite conclusive evidence to the contrary, that the human immunodeficiency virus (HIV) does not cause acquired immune deficiency syndrome (AIDS). Some of its proponents reject the existence of HIV, while others accept that HIV exists but argue that it is a harmless passenger virus and not the cause of AIDS. Insofar as they acknowledge AIDS as a real disease, they attribute it to some combination of sexual behavior, recreational drugs, malnutrition, poor sanitation, haemophilia, or the effects of the medications used to treat HIV infection (antiretrovirals).

<span class="mw-page-title-main">Treatment Action Campaign</span> South African HIV/AIDS activist organization

The Treatment Action Campaign (TAC) is a South African HIV/AIDS activist organisation which was co-founded by the HIV-positive activist Zackie Achmat in 1998. TAC is rooted in the experiences, direct action tactics and anti-apartheid background of its founder. TAC has been credited with forcing the reluctant government of former South African President Thabo Mbeki to begin making antiretroviral drugs available to South Africans.

<span class="mw-page-title-main">Manto Tshabalala-Msimang</span> South African politician

Mantombazana "Manto" Edmie Tshabalala-Msimang OMSS was a South African politician. She was Deputy Minister of Justice from 1996 to 1999 and served as Minister of Health from 1999 to 2008 under President Thabo Mbeki. She also served as Minister in the Presidency under President Kgalema Motlanthe from September 2008 to May 2009.

Mark Arnold Wainberg, was a Canadian HIV/AIDS researcher and HIV/AIDS activist. He was the Director of the McGill University AIDS Centre at the Montreal Jewish General Hospital and Professor of Medicine and of Microbiology at McGill University. His laboratory primarily studies HIV reverse transcriptase, the molecular basis for drug resistance, and gene therapy. He received a B.Sc. from McGill University in 1966, a Ph.D. from Columbia University in 1972, and did his post-doctoral research at Hadassah Medical School of the Hebrew University.

Christine Joy Maggiore was an HIV-positive activist and promoter of HIV/AIDS denialism. She was the founder of Alive & Well AIDS Alternatives, an organization which disputes the link between HIV and AIDS and urges HIV-positive pregnant women to avoid anti-HIV medication. Maggiore authored and self-published the book What If Everything You Thought You Knew about AIDS Was Wrong?

Alive & Well AIDS Alternatives is a 501(c) non-profit organization of AIDS denialists. The organization's stated mission is to "present information that raises questions about the accuracy of HIV tests, the safety and effectiveness of AIDS drug treatments, and the validity of most common assumptions about HIV and AIDS." The organization's founder, Christine Maggiore estimated in 2005 that the organization had assisted about 50 HIV-positive mothers in developing legal strategies to avoid having their children tested or treated for HIV.

<span class="mw-page-title-main">Harvey Bialy</span> American molecular biologist and AIDS denialist

Harvey Bialy was an American molecular biologist and AIDS denialist. He was one of the signatories to a letter to the editor by the "Group for the Scientific Reappraisal of the HIV-AIDS Hypothesis", which denied that HIV was the cause of AIDS, and was a member of the controversial and heavily criticized South African Presidential AIDS Advisory Panel convened by Thabo Mbeki in 2000. Bialy authored a scientific biography of Peter Duesberg, a fellow AIDS denialist, in 2004.

The Durban Declaration is a statement signed by over 5,000 physicians and scientists in 2000, affirming that HIV is the cause of AIDS, seventeen years after the discovery of the Human Immunodeficiency Virus. The declaration was drafted in response to HIV/AIDS denialism, and particularly to address South African president Thabo Mbeki's support for AIDS denialists. It was written several weeks before the 2000 International AIDS Conference, held in Durban, South Africa from July 9 to 14, 2000, and was published in the journal Nature to coincide with the Durban conference. The declaration called the evidence that HIV causes AIDS "clear-cut, exhaustive and unambiguous".

<span class="mw-page-title-main">HIV/AIDS in South Africa</span> Health concern in South Africa

HIV/AIDS is one of the most serious health concerns in South Africa. The country has the highest number of people afflicted with HIV of any country, and the fourth-highest adult HIV prevalence rate, according to the 2019 United Nations statistics.

<span class="mw-page-title-main">Malegapuru William Makgoba</span> South African immunologist, physician, public health advocate and academic

Malegapuru William Makgoba is a leading South African immunologist, physician, public health advocate, academic and former vice-chancellor of the University of KwaZulu-Natal. In 2013 he was recognised as "a pioneer in higher education transformation", by being awarded the Order of Mapungubwe in Silver, but has also generated extensive controversy during that process. He is also responsible for the unjust and unfair dismissal of several high profile academics from UDW and was accused of sexual harassment from his direct staff.

The Perth Group is a group of HIV/AIDS denialists based in Perth, Western Australia who claim, in opposition to the scientific consensus, that the existence of HIV is not proven, and that AIDS and all the "HIV" phenomena are caused by changes in cellular redox due to the oxidative nature of substances and exposures common to all the AIDS risk groups, and are caused by the cell conditions used in the "culture" and "isolation" of "HIV".

Eliza Jane Scovill was the daughter of AIDS denialist Christine Maggiore, an HIV-positive activist who publicly questioned the link between HIV and AIDS, and supported HIV-positive pregnant women who want to avoid taking anti-HIV medication. Eliza Jane's May 16, 2005 death from AIDS, at the age of three and a half, sparked a social and legal controversy over her mother's decision not to take precautions during pregnancy and breastfeeding to prevent transmission of the virus, and her parents' decision to not have her treated for HIV infection during her life.

Seth C. Kalichman is an American clinical community psychologist and professor of social psychology at the University of Connecticut, known for his research into HIV/AIDS treatment and HIV/AIDS denialism. Kalichman is also the director of the Southeast HIV/AIDS Research & Education Project in Atlanta, Georgia, and Cape Town, South Africa, and the editor of the journal AIDS and Behavior. He is the developer of the Sexual Compulsivity Scale.

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In South Africa, HIV/AIDS denialism had a significant impact on public health policy from 1999 to 2008, during the presidency of Thabo Mbeki. Mbeki criticized the scientific consensus that HIV is the cause of AIDS beginning shortly after his election to the presidency. In 2000, he organized a Presidential Advisory Panel regarding HIV/AIDS including several scientists who denied that HIV caused AIDS.

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References

  1. "The cost of South Africa's misguided AIDS policies". News. 15 May 2009. Retrieved 29 August 2017.
  2. Researchers Estimate Lives Lost Due to Delay in Antiretroviral Drug Use for HIV/AIDS in South Africa
  3. "Archived copy" (PDF). Archived from the original (PDF) on 22 December 2009. Retrieved 20 September 2009.{{cite web}}: CS1 maint: archived copy as title (link) Estimating the Lost Benefits of Antiretroviral Drug Use in South Africa
  4. Chigwedere, Pride Mugove. Antiretroviral Drug Use in South Africa: From Science to Practice and Malpractice. Harvard University Publications, 2008
  5. Duesberg PH, Nicholson JM, Rasnick D, Fiala C, Bauer HH (July 2009). "WITHDRAWN: HIV-AIDS hypothesis out of touch with South African AIDS - A new perspective". Medical Hypotheses. doi: 10.1016/j.mehy.2009.06.024 . PMID   19619953.
  6. "Elsevier retracts Duesberg's AIDS Denialist article | AIDSTruth.org". Archived from the original on 4 October 2009. Retrieved 18 September 2009. Elsevier retracts Duesberg’s AIDS Denialist article
  7. Chigwedere Only Student Invited as Editorial Advisor on BMJ Issue Devoted to Africa
  8. Mbeki blamed for 330,000 deaths
  9. Study Cites Toll of AIDS Policy in South Africa
  10. Mbeki Aids denial 'caused 300,000 deaths'
  11. "The Times - Mbeki 'must account for 330,000 deaths'". Archived from the original on 24 November 2008. Retrieved 23 January 2009. Mbeki ‘must account for 330,000 deaths’
  12. A damning documentary about former president Thabo Mbeki's policies on HIV/Aids will be screened on eTV tonight.
  13. Chat about medical care for HIV patients in Africa
  14. "Pride Chigwedere, AIDS researcher, Zimbabwe - AIDS: Learning from the Past, Looking Towards the Future - | Online Lecture | WGBH Forum Network". Archived from the original on 5 September 2009. Retrieved 5 September 2009. AIDS: Learning From the Past, Looking Towards the Future
  15. The Human Toll of South Africa's Early AIDS Policies
  16. Pandemic: Facing AIDS
  17. Business Solutions to AIDS
  18. "The Salem Award: 2006 Symposium". Archived from the original on 24 July 2008. Retrieved 5 September 2009. Out of Africa: The Perils and Promises of the HIV/AIDS Pandemic
  19. "Zimfest 2009 in Boulder Colorado!". Archived from the original on 27 April 2009. Retrieved 5 September 2009. Zimfest 2009
  20. Lowell First Friday Lecture Series
  21. 2006 International Conference on AIDS Orphans and Vulnerable Children
  22. "Be economically active, youths urged | The Herald". www.herald.co.zw. Retrieved 10 August 2017.
  23. "Alumni Awards 2015". Harvard Public Health Magazine. 19 July 2016. Retrieved 10 August 2017.
  24. Razemba, Freeman (16 January 2017). "Zimbabweans Vie for Top AU Posts". The Herald (Harare). Retrieved 10 August 2017.
  25. Wasted Lives
  26. "Harvard School of Public Health AIDS Initiative: Research & Programs: Oak Foundation". Archived from the original on 1 October 2009. Retrieved 5 September 2009. Current and Former Oak Fellows
  27. "Harvard School of Public Health AIDS Initiative: Research & Programs: Fogarty". Archived from the original on 30 March 2009. Retrieved 5 September 2009. 2006 Forgaty Fellows
  28. Harvard's Role in Public Health Crises
  29. "Zimbabwe Medical Graduates Worldwide". Archived from the original on 14 August 2010. Retrieved 5 September 2009.{{cite web}}: CS1 maint: bot: original URL status unknown (link)