Kwashiorkor is a form of severe protein malnutrition characterized by edema and an enlarged liver with fatty infiltrates. It is thought to be caused by sufficient calorie intake, but with insufficient protein consumption, which distinguishes it from marasmus. Recent studies have found that a lack of antioxidant micronutrients such as β-carotene, lycopene, other carotenoids, and vitamin C as well as the presence of aflatoxins may play a role in the development of the disease. However, the exact cause of kwashiorkor is still unknown. Inadequate food supply is correlated with occurrences of kwashiorkor; occurrences in high income countries are rare. It occurs amongst weaning children to ages of about five years old.
Niacin, also known as nicotinic acid, is an organic compound and a vitamer of vitamin B3, an essential human nutrient. It is produced by plants and animals from the amino acid tryptophan. Niacin is obtained in the diet from a variety of whole and processed foods, with highest contents in fortified packaged foods, meat, poultry, red fish such as tuna and salmon, lesser amounts in nuts, legumes and seeds. Niacin as a dietary supplement is used to treat pellagra, a disease caused by niacin deficiency. Signs and symptoms of pellagra include skin and mouth lesions, anemia, headaches, and tiredness. Many countries mandate its addition to wheat flour or other food grains, thereby reducing the risk of pellagra.
The chickpea or chick pea is an annual legume of the family Fabaceae, subfamily Faboideae. Its different types are variously known as gram or Bengal gram, chhola, chhana, chana, or channa, garbanzo or garbanzo bean, or Egyptian pea. Chickpea seeds are high in protein. It is one of the earliest cultivated legumes, the oldest archaeological evidence of which was found in Syria.
Lysine is an α-amino acid that is a precursor to many proteins. Lysine contains an α-amino group, an α-carboxylic acid group, and a side chain (CH2)4NH2, and so it is classified as a basic, charged, aliphatic amino acid. It is encoded by the codons AAA and AAG. Like almost all other amino acids, the α-carbon is chiral and lysine may refer to either enantiomer or a racemic mixture of both. For the purpose of this article, lysine will refer to the biologically active enantiomer L-lysine, where the α-carbon is in the S configuration.
In North America, a corn tortilla or just tortilla is a type of thin, unleavened flatbread, made from hominy, that is the whole kernels of maize treated with alkali to improve their nutrition in a process called nixtamalization. A simple dough made of ground hominy, salt and water is then formed into flat discs and cooked on a very hot surface, generally an iron griddle called a comal.
An essential amino acid, or indispensable amino acid, is an amino acid that cannot be synthesized from scratch by the organism fast enough to supply its demand, and must therefore come from the diet. Of the 21 amino acids common to all life forms, the nine amino acids humans cannot synthesize are valine, isoleucine, leucine, methionine, phenylalanine, tryptophan, threonine, histidine, and lysine.
In agriculture, a milpa is a field for growing food crops and a crop-growing system used throughout Mesoamerica, especially in the Yucatán Peninsula, in Mexico. The word milpa derives from the Nahuatl words milli and pan. Based on the agronomy of the Maya and of other Mesoamerican peoples, the milpa system is used to produce crops of maize, beans, and squash without employing artificial pesticides and artificial fertilizers.
Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B3). Symptoms include inflamed skin, diarrhea, dementia, and sores in the mouth. Areas of the skin exposed to friction and radiation are typically affected first. Over time affected skin may become darker, stiffen, peel, or bleed.
The International Maize and Wheat Improvement Center is a non-profit research-for-development organization that develops improved varieties of wheat and maize with the aim of contributing to food security, and innovates agricultural practices to help boost production, prevent crop disease and improve smallholder farmers' livelihoods. CIMMYT is one of the 15 CGIAR centers. CIMMYT is known for hosting the world's largest maize and wheat genebank at its headquarters in Mexico.
Nixtamalization is a process for the preparation of maize, or other grain, in which the grain is soaked and cooked in an alkaline solution, usually limewater, washed, and then hulled. The term can also refer to the removal via an alkali process of the pericarp from other grains such as sorghum.
Protein digestibility-corrected amino acid score (PDCAAS) is a method of evaluating the quality of a protein based on both the amino acid requirements of humans and their ability to digest it.
A whole grain is a grain of any cereal and pseudocereal that contains the endosperm, germ, and bran, in contrast to refined grains, which retain only the endosperm.
Zeism is any condition attributed to excessive use of maize (corn) in the diet, such as pellagra. Maize is low in zinc, niacin, and tryptophan, and the limited niacin found in maize is not absorbed in the digestive tract unless it has been treated with alkalis, as in the preparation of tortillas. A type of pellagra attributed to amino acid imbalance is common in India among people who eat a millet with a high leucine content. The deficiencies are usually seasonal.
Evangelina Villegas was a Mexican cereal biochemist whose work with maize led to the development of quality protein maize (QPM). She and her colleague from the International Maize and Wheat Improvement Center (CIMMYT), Surinder Vasal, shared the 2000 World Food Prize for this achievement. Villegas was the first woman to ever receive the World Food Prize.
Proteins are essential nutrients for the human body. They are one of the building blocks of body tissue and can also serve as a fuel source. As a fuel, proteins provide as much energy density as carbohydrates: 4 kcal per gram; in contrast, lipids provide 9 kcal per gram. The most important aspect and defining characteristic of protein from a nutritional standpoint is its amino acid composition.
Protein combining or protein complementing is a dietary theory for protein nutrition that purports to optimize the biological value of protein intake. According to the theory, vegetarian and vegan diets may provide an insufficient amount of some essential amino acids, making protein combining with multiple foods necessary to obtain a complete protein food. The terms complete and incomplete are outdated in relation to plant protein. In fact, all plant foods contain all 20 amino acids including the 9 essential amino acids in varying amounts.
Maize, also known as corn in North American English, is a tall stout grass that produces cereal grain. It was domesticated by indigenous peoples in southern Mexico about 9,000 years ago from wild teosinte. Native Americans planted it alongside beans and squashes in the Three Sisters polyculture. The leafy stalk of the plant gives rise to male inflorescences or tassels which produce pollen, and female inflorescences called ears. The ears yield grain, known as kernels or seeds. In modern commercial varieties, these are usually yellow or white; other varieties can be of many colors.
Surinder Vasal is an Indian geneticist and plant breeder, known for his contributions in developing a maize variety with higher content of usable protein. He was born on 12 April 1938 in Amritsar in the Indian state of Punjab and received a PhD in genetics and plant breeding.
Nevin Stewart Scrimshaw was an American food scientist and Institute Professor emeritus at the Massachusetts Institute of Technology. Scrimshaw was born in Milwaukee, Wisconsin. During the course of his long career he developed nutritional supplements for alleviating protein, iodine, and iron deficiencies in the developing world. His pioneering and extensive publications in the area of human nutrition and food science include over 20 books and monographs and hundreds of scholarly articles. Scrimshaw also founded the Department of Nutrition and Food Science at the Massachusetts Institute of Technology, the Institute of Nutrition of Central America and Panama, and the Nevin Scrimshaw International Nutrition Foundation. He was awarded the Bolton L. Corson Medal in 1976 and the World Food Prize in 1991. Scrimshaw spent the last years of his life on a farm in Thornton, New Hampshire, where he died at 95.
Vitamin B3, colloquially referred to as niacin, is a vitamin family that includes three forms, or vitamers: niacin (nicotinic acid), nicotinamide (niacinamide), and nicotinamide riboside. All three forms of vitamin B3 are converted within the body to nicotinamide adenine dinucleotide (NAD). NAD is required for human life and people are unable to make it within their bodies without either vitamin B3 or tryptophan. Nicotinamide riboside was identified as a form of vitamin B3 in 2004.
