U.S. Route 75 is a north–south U.S. Highway that runs 1,239 miles (1,994 km) in the central United States. The highway's northern terminus is located at the Canadian border near Noyes, Minnesota, at a now-closed border crossing. From this point, the highway once continued farther north as Manitoba Highway 75. Its southern terminus is located at Interstate 30 (I-30) and I-45 in Dallas, Texas, where US 75 is known as North Central Expressway.
Interstate 244 (I-244), also known as the Martin Luther King Jr. Memorial Expressway since 1984, the Crosstown Expressway, and the Red Fork Expressway, is a 15.8-mile-long (25.4 km) east–west Interstate Highway bypass route of I-44 in Tulsa, Oklahoma.
U.S. Route 266 is a 43.09-mile (69.35 km), east–west U.S. Numbered Highway in Okmulgee, McIntosh, and Muskogee counties in Oklahoma, United States, that connects U.S. Route 62 U.S. Route 75 in Henryetta with U.S. Route 64 in Warner. The highway no longer meets the former route of its parent, U.S. Route 66, and is closely paralleled by Interstate 40 (I-40), which replaced US 266 as the major east–west highway east of Oklahoma City during the 1960s.
U.S. Route 169 is a north-south U.S highway that currently runs for 966 miles (1,555 km) from the city of Virginia, Minnesota, to Tulsa, Oklahoma, at Memorial Drive.
State Highway 97 is a 19.86-mile (31.96 km) state highway, maintained by the U.S. state of Oklahoma. It connects two towns in the northeast part of the state: Sapulpa and Sand Springs. Several communities of West Tulsa are along the road between these two towns, including Pretty Water, Allen, and Prattville.
State Highway 66 is a 192.7-mile (310.1 km) state highway in the U.S. state of Oklahoma, beginning at U.S. Highway 81 in El Reno and ending at U.S. Highway 60 near White Oak. The highway was designated in 1985 as a replacement for the decommissioned U.S. Highway 66. Although most of the highway follows Historic Route 66, the highway follows US 66's final alignment, joining Interstate 44 through Tulsa and Oklahoma City, while older versions of the route follow various city streets through both cities.
State Highway 20 is a highway in northeastern Oklahoma. Its eastern terminus is at the corner of Oklahoma, Arkansas, and Missouri near Southwest City, Missouri; its western terminus is at State Highway 18 near Ralston. The highway runs a total length of 142.7 miles (229.7 km). It has no lettered spur routes.
State Highway 9, abbreviated as SH-9, OK-9, or simply Highway 9, is a major east–west highway in the U.S. state of Oklahoma. Spanning across the central part of the state, SH-9 begins at the Texas state line west of Vinson, Oklahoma, and ends at the Arkansas state line near Fort Smith, Arkansas. State Highway 9 is a major highway around the Norman area. At 348.1 miles (560.2 km), SH-9 is Oklahoma's second-longest state highway.
State Highway 51, abbreviated to SH-51 or OK-51, is a major state highway in Oklahoma, United States. It runs for 332.8 miles (535.6 km) east–west across the state, running from the Texas state line to Arkansas. It is the third-longest state highway in the system.
State Highway 10 is a state highway in northeastern Oklahoma. It makes a 233.1 miles (375.1 km) crescent through the northeast corner of the state, running from SH-99 in Osage County to Interstate 40 (I-40) near Gore. It has two lettered spur routes.
State Highway 266 is a state highway near Tulsa, Oklahoma, United States. It runs for 10.92 miles (17.57 km) through Tulsa and Rogers Counties in northeastern Oklahoma.
State Highway 165 (SH-165) is a state highway in Muskogee County, Oklahoma. It runs east along Peak Boulevard in the southern part of Muskogee from US-64 to the northern terminus of the southern section of the Muskogee Turnpike, then runs north as a freeway connecting the two sections of the turnpike. The total length of the highway is 8.21 miles (13.21 km).
U.S. Route 69 is a major north-south U.S. Highway in the U.S. state of Oklahoma. It extends the corridor formed by U.S. Route 75 in Texas, from Dallas northeast via McAlester and Muskogee to the Will Rogers Turnpike near Vinita. From Vinita to the Kansas state line, US-69 generally parallels the turnpike along old U.S. Highway 66.
In Oklahoma, U.S. Highway 62 (US 62) runs diagonally across the state, from the Texas state line in far southwestern Oklahoma to the Arkansas state line near Fayetteville. US-62 spends a total of 402.48 miles (647.73 km) in the Sooner State. The highway passes through fifteen of Oklahoma's counties. Along the way the route serves two of Oklahoma's largest cities, Lawton and Oklahoma City, as well as many regionally important cities, like Altus, Chickasha, Muskogee, and Tahlequah. Despite this, US-62 has no lettered spur routes like many other U.S. routes in Oklahoma do.
Six special routes of U.S. Route 75 exist. Two routes exist in Oklahoma, two in Kansas, one in Nebraska, and two in Iowa.
U.S. Route 70 is a transcontinental U.S. highway extending from Globe, Arizona to Atlantic, North Carolina. Along the way, 289.81 miles (466.40 km) of its route passes through the state of Oklahoma. Entering the state south of Davidson, the highway serves Oklahoma's southern tier before exiting the state east of Broken Bow. It serves the cities of Ardmore, Durant, Hugo, and Idabel, as well as Tillman, Cotton, Jefferson, Carter, Marshall, Bryan, Choctaw, and McCurtain counties.
U.S. Route 60 (US-60) is a transcontinental U.S. highway extending from near Brenda, Arizona to Virginia Beach, Virginia on the Atlantic Ocean. Along the way, 352.39 miles (567.12 km) of the route lies within the state of Oklahoma. The highway crosses into the state from Texas west of Arnett and serves many towns and cities in the northern part of the state, including Arnett, Seiling, Fairview, Enid, Ponca City, Pawhuska, Bartlesville, and Vinita. US-60 exits Oklahoma near Seneca, Missouri. In Oklahoma, US-60 has three business routes, serving Tonkawa, Ponca City, and Seneca. The first 60.2 miles (96.9 km) of the route, from the Texas line to Seiling, is also designated as State Highway 51 (SH-51).
U.S. Route 412 is a U.S. highway in the south-central portion of the United States, connecting Springer, New Mexico to Columbia, Tennessee. A 504.11-mile (811.29 km) section of the highway crosses the state of Oklahoma, traversing the state from west to east. Entering the state southwest of Boise City, US-412 runs the length of the Oklahoma Panhandle and serves the northern portion of the state's main body, before leaving the state at West Siloam Springs. Along the way, the route serves many notable cities and towns, including Boise City, Guymon, Woodward, Enid, and the state's second-largest city, Tulsa.
U.S. Route 64 (US-64) is a U.S. highway running from the Four Corners area to the Outer Banks of North Carolina. Between these two points, the highway passes through the entire width of Oklahoma; a total of 591.17 miles (951.40 km) of US-64 lies in the state of Oklahoma. US-64 enters the state from New Mexico, crossing the line between the two states between Clayton, New Mexico, and Boise City in Cimarron County. The route runs the full length of the Oklahoma Panhandle, then serves the northernmost tier of counties in the main body of the state before dipping southeastward to Tulsa, the state's second-largest city. From Tulsa, the highway continues southeast, leaving Oklahoma just west of Fort Smith, Arkansas. In addition to Tulsa, US-64 serves fifteen Oklahoma counties and the cities of Guymon, Woodward, Enid, and Muskogee.
U.S. 75 Alternate is a 30.15-mile (48.52 km) highway near Tulsa. The southern terminus is at U.S. Highway 75 and SH-16 east of Beggs. The northern terminus is signed at State Highway 66 and State Highway 97 in Sapulpa. However, the highway continues unsigned along SH-66, ending at the north terminus of the Turner Turnpike, where SH-66 merges onto the free portion of I-44. It runs parallel to US-75 for its entire length.
US 64 / Creek Turnpike in Tulsa 
I-44 / SH-66 in Tulsa
I-244 / US 412 in Tulsa
US 60 near Nowata 
US-169 at the Kansas state line
