State Route 58 is a major east-west state highway in the U.S. state of California that runs across the Coast Ranges, the southern San Joaquin Valley, the Tehachapi Mountains, which border the southern Sierra Nevada, and the Mojave Desert. It runs between U.S. Route 101 near Santa Margarita and Interstate 15 in Barstow. It has junctions with Interstate 5 near Buttonwillow, State Route 99 in Bakersfield, State Route 202 in Tehachapi, State Route 14 near Mojave, and U.S. Route 395 at Kramer Junction. SR 58 also provides access to Edwards Air Force Base. At various points it is known as the Calf Canyon Highway, Carrisa Highway, Bakersfield-McKittrick Highway, Rosa Parks Highway, Westside Parkway, Barstow-Bakersfield Highway, Bakersfield Tehachapi Highway, Kern County Korean War Veterans Memorial Highway, and Mojave-Barstow Highway.
State Route 120 is a state highway in the central part of California, connecting the San Joaquin Valley with the Sierra Nevada, Yosemite National Park, and the Mono Lake area. Its western terminus is at Interstate 5 in Lathrop, and its eastern terminus is at U.S. Route 6 in Benton. While the route is signed as a contiguous route through Yosemite, the portion inside the park is federally maintained and is not included in the state route logs. The portion at Tioga Pass at Yosemite's eastern boundary is the highest paved through road in the California State Route system. This part is not maintained in the winter and is usually closed during the winter season.
State Route 118 is a state highway in the U.S. state of California that runs west to east through Ventura and Los Angeles counties. It travels from State Route 126 at the eastern edge of Ventura immediately northwest of Saticoy, then through Saticoy, in Ventura County east to Interstate 210 near Lake View Terrace in Los Angeles. SR 118 crosses the Santa Susana Pass and the northern rim of the San Fernando Valley along its route.
State Route 299 is an east–west state highway in the U.S. state of California that runs across the northern part of the state. At 305.777 miles (492.100 km), it is the third longest California state route, after Route 1 and Route 99, and the longest east-west route. Route 299's western terminus is at US 101 at the northern edge of Arcata, and its eastern terminus is at the Nevada state line at a point east of Cedarville. Between Arcata and Redding, Route 299 intersects with State Route 96, and is briefly co-signed with State Route 3. In Redding, it intersects with State Route 273, State Route 44, and Interstate 5. East of Redding, it intersects with State Route 89, and a section is co-signed with State Route 139 before reaching Alturas. It is then co-signed with U.S. Route 395 northeast of Alturas, and then runs east through Cedarville and to the border with Nevada. A ghost town, Vya, Nevada, can be reached via this route, which after the border becomes a dirt road, which was formerly Nevada State Route 8A. The segment of SR 299 between Arcata and Redding is the Trinity Scenic Byway, a National Forest Scenic Byway.
State Route 12 is a state highway in the U.S. state of California that travels in an east–west direction from State Route 116 in Sebastopol in Sonoma County to State Route 49 just north of San Andreas in Calaveras County. The route connects the Sonoma and Napa valleys with the Sacramento–San Joaquin River Delta and the Sierra Foothills. It is constructed to freeway standards from the Fulton Road/South Wright Road stoplight in Santa Rosa, to its partial interchange with Farmers Lane.
State Route 33 is a north–south state highway in the U.S. state of California. It runs north from U.S. Route 101 in Ventura through the Transverse Ranges and the western side of the San Joaquin Valley to Interstate 5 at a point east of Tracy. SR 33 replaced part of U.S. Route 399 in 1964 during the "great renumbering" of routes. In the unincorporated sections of Kern County it is known as the West Side Highway. In addition, the California Legislature designated the entire Kern County portion as the Petroleum Highway in 2004. The southernmost portion in Ventura is a freeway known as the Ojai Freeway, while it is known as the Maricopa Highway from Ojai to Maricopa.
State Route 20 is a state highway in the northern-central region of the U.S. state of California, running east–west north of Sacramento from the North Coast to the Sierra Nevada. Its west end is at SR 1 in Fort Bragg, from where it heads east past Clear Lake, Colusa, Yuba City, Marysville and Nevada City to I-80 near Emigrant Gap, where eastbound traffic can continue on other routes to Lake Tahoe or Nevada.
State Route 89 is a state highway in the U.S. state of California that travels in the north–south direction, serving as a major thoroughfare for many mountain communities in the Sierra Nevada and the Cascade Range. It starts from U.S. Route 395 near Topaz Lake, winding its way up to the 8,314-foot (2,534 m) Monitor Pass, down to the Carson River, and up again over the 7,740-foot (2,359 m) Luther Pass. From that point on, the route generally loses elevation on its way past Lake Tahoe, through Tahoe and Plumas National Forests until Lake Almanor. For roughly nine miles the route is then a part of State Route 36. The route then ascends to the 5,753-foot (1,754 m) Morgan Summit. After it enters Lassen Volcanic National Park it continues to gain elevation until it reaches its highest point in an unnamed pass in the middle of Lassen Peak and Bumpass Mountain. The road then descends and heads northwest, finally terminating at Interstate 5 at the foot of Mount Shasta at around 3,600 feet (1,100 m).
State Route 26 is a state highway in the U.S. state of California, running from State Route 99 in Stockton in San Joaquin County to State Route 88 near Pioneer in Amador County. The highway is routed to serve Mokelumne Hill and West Point in Calaveras County.
State Route 28 is a state highway in the U.S. state of California that travels along the northern shore of Lake Tahoe, starting at Route 89 in Tahoe City and ending at the Nevada state border, whereupon it becomes Nevada State Route 28.
State Route 32 is an east–west state highway in the U.S. State of California which is routed from Interstate 5 in Orland, across the Sacramento Valley and through Chico, through the northern Sierra Nevada, and ending at SR 36 and SR 89 in eastern Tehama County.
State Route 198 is an east–west state highway in the U.S. state of California that runs from U.S. Route 101 south of King City to Sequoia National Park. It connects the California Central Coast to the mid–Central Valley through Hanford and Visalia, although the most developed portion is in the Central Valley itself. SR 198 intersects the major north–south routes in the Central Valley, including Interstate 5 (I-5), SR 33, and SR 99.
State Route 108 is a state highway in the U.S. state of California that runs from the Central Valley and across the Sierra Nevada via the Sonora Pass. It generally runs northeast from downtown Modesto near the SR 99/SR 132 interchange, to U.S. Route 395 near the Nevada state line. The route was once recommended to continue south of Modesto to Interstate 5, although today that portion exists as a county road. Parts of SR 108 are closed annually during the winter due to inclement weather along the summit.
State Route 127 is a state highway in the U.S. state of California that connects Interstate 15 in Baker to Nevada State Route 373 at the Nevada state line, passing near the eastern boundary of Death Valley National Park. The entire length of the highway closely follows the central portion of the former Tonopah and Tidewater Railroad and loosely follows the Amargosa River.
State Route 168 is an east-west state highway in the U.S. state of California that is separated into two distinct segments by the Sierra Nevada. The western segment runs from State Routes 41 and 180 in Fresno east to Huntington Lake along the western slope of the Sierra. The eastern segment connects Lake Sabrina in the Eastern Sierra to State Route 266 in the community of Oasis, just to the west of the Nevada border. The eastern segment of SR 168 also forms a concurrency with U.S. Route 395 between Bishop and Big Pine.
State Route 178 is a state highway in the U.S. state of California that exists in two constructed segments. The gap in between segments is connected by various local roads and State Route 190 through Death Valley National Park. The western segment runs from State Route 99 in Bakersfield and over the Walker Pass in the Sierra Nevada to the turnoff for the Trona Pinnacles National Natural Landmark. The eastern segment runs from the southeasterly part of Death Valley to Nevada State Route 372 at the Nevada state line.
State Route 167 is a state highway in the U.S. state of California in Mono County. From U.S. Route 395, SR 167 runs along Pole Line Road north of Mono Lake eastward to the Nevada state line where it meets Nevada State Route 359. This road runs almost completely straight, and can be seen almost 15 miles (24 km) into the distance as a straight line.
State Route 174 is a state highway in the U.S. state of California. The two-lane 13-mile (21 km) highway in the western Sierra Nevada, added to the state highway system in 1933, connects Interstate 80 in Colfax with SR 20/SR 49 in Grass Valley, crossing the Bear River next to a 1924 concrete arch bridge. The majority of the route is eligible for the State Scenic Highway System, but local residents have blocked its designation due to property right concerns.
U.S. Route 395 (US 395) is a United States Numbered Highway, stretching from Hesperia, California to the Canadian border in Laurier, Washington. The California portion of US 395 is a 557-mile (896 km) route which traverses from Interstate 15 (I-15) in Hesperia, north to the Oregon state line in Modoc County near Goose Lake. The route clips into Nevada, serving the cities Carson City and Reno, before returning to California.
U.S. Route 95 (US 95) is a United States Numbered Highway, stretching from the Mexican border in San Luis, Arizona to the Canadian border near Eastport, Idaho. The California portion of US 95 traverses through the far eastern edges of both Riverside and San Bernardino counties. US 95 serves Blythe and Needles and junctions with SR 62 at Vidal Junction.
US 395 in Bishop 
SR 120 in Benton 
US 6 at Nevada state line southwest of Coaldale, NV 
