11C ME@HAPTHI

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11C ME@HAPTHI
11C ME@HAPTHI.svg
Identifiers
  • (S)-1-(3-Hydroxy-4-([11C]methylamino)butyl)-3-phenyl-1,3-dihydrobenzo[c][1,2,5]thiadiazole,2,2-dioxide
CAS Number
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
Formula C17H21N3O3S
Molar mass 347.43 g·mol−1
3D model (JSmol)
  • [11CH3]NC[C@@H](O)CCN1C2=C(C=CC=C2)N(C2=CC=CC=C2)S1(=O)=O

[11C]ME@HAPTHI is a chemical compound used as a radiotracer to image the norepinephrine transporter (NET) protein using positron emission tomography (PET). [1] The NET protein is of research interest for its role in various neuropsychiatric disorders, such as ADHD and depression. [1]

References

  1. 1 2 Rami-Mark C, Berroterán-Infante N, Philippe C, Foltin S, Vraka C, Hoepping A, Lanzenberger R, Hacker M, Mitterhauser M, Wadsak W (Dec 2015). "Radiosynthesis and first preclinical evaluation of the novel norepinephrine transporter pet-ligand [(11)C]ME@HAPTHI". EJNMMI Research. 5 (34): 113. doi: 10.1186/s13550-015-0113-3 . PMC   4467816 . PMID   26061602.


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