Martina Navratilova and Bob Bryan defeated Květa Peschke and Martin Damm in the final, 6–2, 6–3 to win the mixed doubles tennis title at the 2006 US Open. It was Navratilova's 59th and final major title, 32 years after her first.
Chris Evert defeated Helena Suková in the final, 6–7(4–7), 6–1, 6–3 to win the women's singles tennis title at the 1984 Australian Open. It was her second Australian Open singles title and her 16th major singles title overall. With her third round victory, Evert became the first player in the Open Era to win 1,000 matches. She finished the tournament with a 1,003-97 career match record.
Martina Navratilova defeated the defending champion Chris Evert in the final, 6–3, 6–1 to win the women's singles tennis title at the 1984 French Open. With the win, Navratilova completed a non-calendar-year Grand Slam, dubbed the 'Martina Slam', and became only the second woman in the Open Era to simultaneously hold all four major singles titles. It was Navratilova's second French Open singles title and ninth major singles title overall.
Martina Navratilova defeated the defending champion Chris Evert in the final, 6–1, 6–3 to win the women's singles tennis title at the 1983 US Open. With the win, she completed the career Grand Slam in singles. It was her first US Open singles title and seventh major singles title overall.
Steffi Graf defeated Gabriela Sabatini in the final, 6–3, 3–6, 6–1 to win the women's singles tennis title at the 1988 US Open. It was her first US Open singles title and fifth major title overall. With the win, she became the third woman to achieve the calendar Grand Slam, after Maureen Connolly and Margaret Court. Moreover, it was the fourth component of her calendar Golden Slam, which remains the only calendar Golden Slam achieved in tennis, men or women. It was Sabatini's maiden major final.
Samantha Stosur and Scott Draper defeated Liezel Huber and Kevin Ullyett in the final 6–2, 2–6, [10–6] to win the mixed doubles title at the 2005 Australian Open. This was the first Grand Slam title for both Stosur and Draper, and would be Draper's only Grand Slam title.
Jelena Janković was the defending champion, but chose not to participate that year.
Vera Zvonareva and Bob Bryan were the defending champions, but Zvonareva did not participate in this U.S. Open due to injury. Bryan partnered Rennae Stubbs, and the pair lost in the quarterfinals to Corina Morariu and Mike Bryan.
Serena Williams and Venus Williams were the defending champions from 2010; however, they were unable to defend their title because of Serena's foot injury, sustained in the middle of the 2010 season.
Three-time defending champions Martina Navratilova and Pam Shriver successfully defended their title, defeating Kathy Jordan and Anne Smith in the final, 6–3, 6–4 to win the ladies' doubles tennis title at the 1984 Wimbledon Championships. It was the second step in an eventual Grand Slam for the pair.
Gigi Fernández and Robin White were the defending champions but lost in the quarterfinals to Steffi Graf and Gabriela Sabatini.
Two-time defending champions Martina Navratilova and Pam Shriver defeated Claudia Kohde-Kilsch and Helena Suková in the final, 6–3, 6–4 to win the women's doubles tennis title at the 1984 Australian Open. With the win, they became the third and fourth women in history to complete a Grand Slam in women's doubles.
Defending champion Serena Williams successfully defended her title, defeating Victoria Azarenka in a rematch of the previous year's final, 7–5, 6–7(6–8), 6–1 to win the women's singles tennis title at the 2013 US Open. It was her fifth US Open singles title and her 17th major singles title overall. For the second consecutive year, Williams lost only one set during the tournament, to Azarenka in the final.
Martina Navratilova and Pam Shriver were the defending champions and successfully defended their title, defeating Claudia Kohde-Kilsch and Helena Suková in the final 4–6, 6–2, 6–2. This was their 8th successive Grand Slam title in women's doubles.
Virginia Ruano Pascual and Paola Suárez were the defending champions and won in the final 6–2, 6–3, against Svetlana Kuznetsova and Martina Navratilova in straight sets. This was Ruano Pascual's 4th career Grand Slam doubles title and her 2nd title at the US Open. It was also Suárez' 4th career Grand Slam doubles title and her 2nd title at the US Open.
Cara Black and Wayne Black were the defending champions, but lost in semifinals to Lisa Raymond and Mike Bryan.
Martina Navratilova and Leander Paes defeated Eleni Daniilidou and Todd Woodbridge in the final, 6–4, 7–5 to win the mixed doubles tennis title at the 2003 Australian Open. It was Navratilova's first Australian Open mixed doubles title and eighth mixed doubles title overall, and the first Australian Open and second mixed doubles title for Paes. With the win, Navratilova became the fourth woman in history to complete the career Grand Slam in mixed doubles, and became only the third player in history to complete the "Boxed Set".
Martina Hingis and Leander Paes defeated Sania Mirza and Ivan Dodig in the final, 4–6, 6–4, [10–8] to win the mixed doubles tennis title at the 2016 French Open. Hingis and Paes each completed the individual career Grand Slam with the win, as well as the team career Grand Slam. Paes also tied Martina Navratilova's record for the most major mixed doubles titles (10) in the Open Era.
Ann Kiyomura and Kazuko Sawamatsu were the defending champions, but Sawamatsu did not compete. Kiyomura partnered with Mona Guerrant, but they lost in the third round to Lesley Charles and Sue Mappin.
Elise Mertens and Aryna Sabalenka were the defending champions, but lost in the quarterfinals to Laura Siegemund and Vera Zvonareva.
Victoria Azarenka 
Meghann Shaughnessy 
Leander Paes 
