2022–2023 mpox outbreak in the United States

Last updated

2022–2024 mpox outbreakin the United States
Monkeypox Outbreak United States Cases by State.svg
Spread of mpox by US state as of September 24, 2022
Disease Mpox
Virus strain Monkeypox virus (West African clade)
Location United States
Index case Boston, Massachusetts [1]
Arrival dateMay 17, 2022 (2 years, 4 months, 3 weeks and 6 days ago)
Dateas of August 31, 2024
Confirmed cases33,590 [2]
Deaths
60 [2]
Government website
www.cdc.gov/poxvirus/mpox/response/2022/

The 2022–2023 mpox outbreak in the United States was part of the larger outbreak of human mpox caused by the West African clade of the monkeypox virus. The United States was the fourth country outside of the African countries with endemic mpox to experience an outbreak in 2022. The first case was documented in Boston, Massachusetts, on May 17, 2022. [3] As of August 2022, mpox had spread to all 50 states in the United States, as well as Washington, D.C., and Puerto Rico. [4] The United States had the highest number of mpox cases in the world during the outbreak. [5] California had the highest number of mpox cases in the United States.

Contents

On August 4, 2022, the U.S. Centers for Disease Control and Prevention declared mpox a public health emergency in the United States. [6] Wyoming was the last state in the United States to report at least one mpox case. On August 30, 2022, the first mpox death in the United States was reported. [7]

Background

Mpox ( /ˈɛmpɒks/ , EM-poks; formerly known as monkeypox) [8] is an infectious viral disease that can occur in humans and other animals. Symptoms include a rash that forms blisters and then crusts over, fever, and swollen lymph nodes. The illness is usually mild, and most infected individuals recover within a few weeks without treatment. The time from exposure to the onset of symptoms ranges from three to seventeen days, and symptoms typically last from two to four weeks. However, cases may be severe, especially in children, pregnant women, or people with suppressed immune systems. [9] [10] [11]

The disease is caused by the monkeypox virus, a zoonotic virus in the genus Orthopoxvirus . The variola virus, which causes smallpox, is also in this genus. [12] Human-to-human transmission can occur through direct contact with infected skin or body fluids, including sexual contact. [12] People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. [9] The virus may spread from infected animals through handling infected meat or via bites or scratches. [9] Diagnosis can be confirmed by polymerase chain reaction (PCR) testing a lesion for the virus's DNA. [12]

An ongoing outbreak of mpox was confirmed on May 6, 2022, beginning with a British resident who, after travelling to Nigeria (where the disease is endemic), presented symptoms consistent with mpox on April 29, 2022. The resident returned to the United Kingdom on May 4, creating the country's index case of the outbreak. [13] The origin of several of the cases of mpox in the United Kingdom is unknown. Some monitors saw community transmission taking place in the London area as of mid-May, [14] but it has been suggested that cases were already spreading in Europe in the previous months. [15]

Transmission

Stages of lesion development. Stages of monkeypox lesion development.jpg
Stages of lesion development.

A large portion of those infected were believed to have not recently traveled to areas of Africa where mpox is normally found, such as Nigeria, the Democratic Republic of the Congo as well as central and western Africa. It is believed to be transmitted by close contact with sick people, with extra caution for those individuals with lesions on their skin or genitals, along with their bedding and clothing. The CDC has also stated that individuals should avoid contact and consumption of dead animals such as rats, squirrels, monkeys, and apes along with wild game or lotions derived from animals in Africa. [16]

In addition to more common symptoms, such as fever, headache, swollen lymph nodes, and rashes or lesions, some patients have also experienced proctitis, an inflammation of the rectum lining. CDC has also warned clinicians to not rule out mpox in patients with sexually transmitted infections since there have been reports of co-infections with syphilis, gonorrhea, chlamydia, and herpes. [17]

The CDC has stated that, among mpox cases with available data, 99% occurred in men, 94% of whom reported recent male-to-male sexual or close intimate contact. [18]

Cases transited through the United States

California

The 2022–2023 mpox outbreak in California. As of July 2022, the virus has infected 4,886 people in the U.S. state of California, with 1 death. The state has the highest number of recorded cases in the country. [19]

Florida

Florida currently has 2,444 people infected by the virus, with no deaths. It started on May 23, 2022, in Fort Lauderdale and quickly started spreading across the State. [20] [21]

New York

The 2022–2023 mpox outbreak in New York currently has no deaths. This state has the second highest number of recorded cases in the country with 3,679 cases. [22]

In New York the outbreak began on June 10, 2022, with the first mpox case recorded in Ithaca. [22] On July 29, Governor Kathy Hochul declared a public state disaster emergency in New York State. [23] New York is currently the state with the highest recorded number of cases in the US. [22]

The World Health Organization in New York reports its first mpox case outside New York City on June 7. [24]

On July 13, New York becomes the epicenter of the outbreak. With 489 cases only behind California with 266 cases. [25]

On July 27, New York reaches 1,228 cases, with an increase of 739 cases in only 14 days. [26]

On August 1, Mayor Eric Adams declares a state of emergency over the mpox outbreak. [27]

Cases by county

Based from the NYSDOH. [28]

Cases of mpox
CountyCasesChange [lower-alpha 1]
Albany 3(+0)
Broome 1(+0)
Chemung 1(+0)
Columbia 1(+0)
Dutchess 5(+0)
Erie 5(+0)
Greene 1(+0)
Monroe 7(+0)
Nassau 14(+0)
Niagara 1(+0)
Orange 6(+0)
Rockland 4(+0)
St. Lawrence 1(+0)
Suffolk 25(+0)
Sullivan 2(+0)
Tompkins 2(+0)
Westchester 50(+0)
New York City 1,831(+0)
Total cases1,960(+0)
As of August 8,2022 at 2:00 pm Eastern Time

Timeline

Mpox cases in United States  (
)
     Deaths        Confirmed cases
2022202220232023
MayMayJunJunJulJulAugAugSepSepOctOctNovNovDecDec
JanJanFebFebMarMar
Last 15 daysLast 15 days
Date
Cases (rise)
Deaths (rise)
2022-05-181(n.a.)
2022-05-191(=)
2022-05-20
2(+1)
2022-05-21
2(=)
2022-05-22
2(=)
2022-05-23
2(=)
2022-05-24
2(=)
2022-05-25
4(+2)
2022-05-26
9(+5)
2022-05-27
12(+3)
2022-05-28
12(=)
2022-05-29
14(+2)
2022-05-30
14(=)
2022-05-31
19(+5)
2022-06-01
19(=)
2022-06-02
23(+4)
2022-06-03
25(+2)
2022-06-04
25(=)
2022-06-05
25(=)
2022-06-06
26(+1)
2022-06-07
31(+5)
2022-06-08
35(+4)
2022-06-09
40(+5)
2022-06-10
47(+7)
2022-06-11
49(+2)
2022-06-12
49(=)
2022-06-13
65(+16)
2022-06-14
72(+7)
2022-06-15
84(+12)
2022-06-16
100(+16)
2022-06-17
113(+13)
2022-06-18
113(=)
2022-06-19
113(=)
2022-06-20
113(=)
2022-06-21
113(=)
2022-06-22
156(+43)
2022-06-23
181(+25)
2022-06-24
201(+20)
2022-06-25
201(=)
2022-06-26
201(=)
2022-06-27
244(+43)
2022-06-28
306(+62)
2022-06-29
351(+45)
2022-06-30
396(+45)
2022-07-01
460(+64)
2022-07-02
460(=)
2022-07-03
460(=)
2022-07-04
460(=)
2022-07-05
560(+100)
2022-07-06
605(+45)
2022-07-07
700(+95)
2022-07-08
767(+67)
2022-07-09
767(=)
2022-07-10
767(=)
2022-07-11
866(+99)
2022-07-12
929(+63)
2022-07-13
1,052(+123)
2022-07-14
1,470(+418)
2022-07-15
1,814(+344)
2022-07-16
1,814(=)
2022-07-17
1,814(=)
2022-07-18
1,972(+158)
2022-07-19
2,108(+136)
2022-07-20
2,323(+215)
2022-07-21
2,593(+270)
2022-07-22
2,891(+298)
2022-07-23
2,891(=)
2022-07-24
2,891(=)
2022-07-25
3,487(+596)
2022-07-26
3,591(+104)
2022-07-27
4,639(+1,048)
2022-07-28
4,907(+268)
2022-07-29
5,189(+282)
2022-07-30
5,189(=)
2022-07-31
5,189(=)
2022-08-01
5,811(+622)
2022-08-02
6,326(+515)
2022-08-03
6,617(+291)
2022-08-04
7,102(+485)
2022-08-05
7,510(+408)
2022-08-06
7,510(=)
2022-08-07
7,510(=)
2022-08-08
8,934(+1,424)
2022-08-09
9,492(+558)
2022-08-10
10,389(+897)
2022-08-11
10,768(+379)
2022-08-12
11,177(+409)
2022-08-13
11,177(=)
2022-08-14
11,177(=)
2022-08-15
11,890(+713)
2022-08-16
12,689(+799)
2022-08-17
13,517(+828)
2022-08-18
14,115(+598)
2022-08-19
14,115(=)
2022-08-20
14,115(=)
2022-08-21
14,115(=)
2022-08-22
15,433(+1,318)
2022-08-23
15,909(+476)
2022-08-24
16,603(+694)
2022-08-25
16,926(+323)
2022-08-26
17,432(+506)
2022-08-27
17,432(=)
2022-08-28
17,432(=)
2022-08-29
18,101(+669)
2022-08-30
18,417(+316)1(n.a.)
2022-08-31
18,989(+572)1(=)
2022-09-01
19,465(+476)1(=)
2022-09-02
19,962(+497)1(=)
2022-09-03
19,962(=)1(=)
2022-09-04
19,962(=)1(=)
2022-09-05
19,962(=)1(=)
2022-09-06
20,733(+771)1(=)
2022-09-07
21,274(+541)1(=)
2022-09-08
21,504(+230)1(=)
2022-09-09
21,894(+390)1(=)
2022-09-10
21,894(=)1(=)
2022-09-11
21,894(=)1(=)
2022-09-12
21,894(=)1(=)
2022-09-13
22,630(+736)1(=)
2022-09-14
22,774(+144)1(=)
2022-09-15
22,774(=)1(=)
2022-09-16
23,499(+725)1(=)
2022-09-17
23,499(=)1(=)
2022-09-18
23,499(=)1(=)
2022-09-19
23,893(+394)1(=)
2022-09-20
23,893(=)1(=)
2022-09-21
23,893(=)1(=)
2022-09-22
24,572(+679)1(=)
2022-09-23
24,846(+274)1(=)
2022-09-24
24,846(=)1(=)
2022-09-25
24,846(=)1(=)
2022-09-26
25,155(+309)1(=)
2022-09-27
25,341(+186)1(=)
⋮
2022-09-30
25,851(n.a.)1(n.a.)
⋮
2022-10-04
26,194(n.a.)1(n.a.)
2022-10-05
26,311(+117)1(=)
2022-10-06
26,385(+74)1(=)
2022-10-07
26,577(+192)1(=)
⋮
2022-10-19
27,635(n.a.)1(n.a.)
⋮
2022-11-18
29,133(n.a.)13(n.a.)
⋮
2022-11-23
29,199(n.a.)13(n.a.)
⋮
2022-12-30
29,367(n.a.)15(n.a.)
⋮
2023-3-1
30,225(n.a.)38(n.a.)

The first known case was detected on May 18, 2022, in a man from Boston, Massachusetts, who had traveled to Canada, where a case of the virus was reported the following day. [29] [30] The person was hospitalized in Boston. [31] There, he tested positive for mpox, becoming the first case in the United States. [29]

Two days after the man tested positive for the virus, other states began reporting cases, with New York reporting its first case on May 21. [32] On May 22, President Biden gave a speech at Osan Air Base in South Korea during which he indicated the disease was "something that everybody should be concerned about". [33] On May 26, Virginia reported its first case in a woman who had traveled to Africa, [34] followed by California and Hawaii on June 4, 2022. [35] [36] As of June 3, the United States had 21 confirmed cases, [37] a number which had risen to 460 as of July 1. [38]

On May 23, 2022, Florida reported a case of mpox. On the same day, the Tampa Bay Times reported that the Florida Department of Health had announced the case on a man that had been isolated since the day before. [20] WESH later on also confirmed the case, which was in Broward County. [39] The following day, WESH reported another mpox case as being "investigated". [40] The case was then confirmed to be in the same county as the first case, adding up the total in the county to two. Later, a third case was also investigated, this time being reported by CBS Miami to also be in the same county as the first and second case. [41] This case added up the total in the United States to 18. A fourth case was reported by the Sun-Sentinel , although the state of Florida did not disclose the county where it was detected. [42]

In early June 2022, a man in Washington, D.C., was reported to test positive for orthopox, potentially mpox. [43]

On July 26, 2022, the United States had more mpox cases than any other country. [44] At the end of August 2022, there were early signs that the mpox spread in the U.S. may be slowing. [45]

Ref:

Cases by state

Data sourced from the CDC [46]

Cases of mpox
StateCasesChange [lower-alpha 2]
Flag of Alabama.svg  Alabama 186(+74)
Flag of Alaska.svg  Alaska 5—
Flag of Arizona.svg  Arizona 580(+134)
Flag of Arkansas.svg  Arkansas 72(+16)
Flag of California.svg  California 5,670(+784)
Flag of Colorado.svg  Colorado 407(+144)
Flag of Connecticut.svg  Connecticut 144(+20)
Flag of Delaware.svg  Delaware 43(+7)
Flag of Washington, D.C.svg  District of Columbia 525(+31)
Flag of Florida.svg  Florida 2,855(+411)
Flag of Georgia (U.S. state).svg  Georgia 1,984(+248)
Flag of Hawaii.svg  Hawaii 35(+8)
Flag of Idaho.svg  Idaho 16(+4)
Flag of Illinois.svg  Illinois 1,422(+152)
Flag of Indiana.svg  Indiana 285(+62)
Flag of Iowa.svg  Iowa 29(+4)
Flag of Kansas.svg  Kansas 47(+38)
Flag of Kentucky.svg  Kentucky 97(+46)
Flag of Louisiana.svg  Louisiana 306(+63)
Flag of Maine.svg  Maine 13(+4)
Flag of Maryland.svg  Maryland 739(+103)
Flag of Massachusetts.svg  Massachusetts 456(+75)
Flag of Michigan.svg  Michigan 395(+138)
Flag of Minnesota.svg  Minnesota 234(+52)
Flag of Mississippi.svg  Mississippi 108(+35)
Flag of Missouri.svg  Missouri 209(+101)
Flag of Montana.svg  Montana 7(+2)
Flag of Nebraska.svg  Nebraska 31(+3)
Flag of Nevada.svg  Nevada 319(+101)
Flag of New Hampshire.svg  New Hampshire 33(+4)
Flag of New Jersey.svg  New Jersey 764(+81)
Flag of New Mexico.svg  New Mexico 57(+17)
Flag of New York.svg  New York 4,203(+361)
Flag of North Carolina.svg  North Carolina 728(+216)
Flag of North Dakota.svg  North Dakota 6—
Flag of Ohio.svg  Ohio 263(+128)
Flag of Oklahoma.svg  Oklahoma 68(+32)
Flag of Oregon.svg  Oregon 270(+65)
Flag of Pennsylvania.svg  Pennsylvania 864(+128)
Flag of Puerto Rico.svg  Puerto Rico 198(+28)
Flag of Rhode Island.svg  Rhode Island 84(+11)
Flag of South Carolina.svg  South Carolina 226(+70)
Flag of South Dakota.svg  South Dakota 3(+1)
Flag of Tennessee.svg  Tennessee 392(+119)
Flag of Texas.svg  Texas 2,882(+657)
Flag of Utah.svg  Utah 194(+45)
Flag of Vermont.svg  Vermont 3—
Flag of Virginia.svg  Virginia 564(+112)
Flag of Washington.svg  Washington 658(+75)
Flag of West Virginia.svg  West Virginia 12(+1)
Flag of Wisconsin.svg  Wisconsin 87(+18)
Flag of Wyoming.svg  Wyoming 4(+2)
Total cases29782(+4,936)
As of January 4, 2023 at 2:00 pm EDT

Timeline of first confirmed cases by state

First confirmed mpox cases by state
DateStates
May 18, 2022Flag of Massachusetts.svg  Massachusetts [47]
May 21, 2022Flag of New York.svg  New York [48]
May 23, 2022Flag of Florida.svg  Florida [49]
May 25, 2022Flag of Utah.svg  Utah [50]
May 26, 2022Flag of Virginia.svg  Virginia [51] • Flag of Colorado.svg  Colorado [52]
May 27, 2022Flag of Washington.svg  Washington [53] • Flag of California.svg  California [54]
June 2, 2022Flag of Pennsylvania.svg  Pennsylvania [55] • Flag of Illinois.svg  Illinois [56]
June 3, 2022Flag of Hawaii.svg  Hawaii [57]
June 5, 2022Flag of Washington, D.C.svg  District of Columbia [58]
June 6, 2022Flag of Georgia (U.S. state).svg  Georgia [59]
June 7, 2022Flag of Texas.svg  Texas [60]
June 9, 2022Flag of Rhode Island.svg  Rhode Island [61]
June 14, 2022Flag of Ohio.svg  Ohio [62] • Flag of Oklahoma.svg  Oklahoma [63]
June 15, 2022Flag of Nevada.svg  Nevada [64]
June 16, 2022Flag of Maryland.svg  Maryland [65] • Flag of Oregon.svg  Oregon [66]
June 18, 2022Flag of Indiana.svg  Indiana [67]
June 20, 2022Flag of New Jersey.svg  New Jersey [68]
June 22, 2022Flag of Missouri.svg  Missouri [69]
June 23, 2022Flag of North Carolina.svg  North Carolina [70]
June 24, 2022Flag of Kentucky.svg  Kentucky [71]
June 17, 2022Flag of Nebraska.svg  Nebraska [72] • Flag of Minnesota.svg  Minnesota [73]
June 29, 2022Flag of New Hampshire.svg  New Hampshire [74] • Flag of Michigan.svg  Michigan [75]
June 30, 2022Flag of Wisconsin.svg  Wisconsin [76]
July 1, 2022Flag of Iowa.svg  Iowa [77]
July 5, 2022Flag of Connecticut.svg  Connecticut [78]
July 6, 2022Flag of Arkansas.svg  Arkansas [79] • Flag of Idaho.svg  Idaho [80]
July 7, 2022Flag of Louisiana.svg  Louisiana [81] • Flag of Tennessee.svg  Tennessee [82]
July 8, 2022Flag of South Carolina.svg  South Carolina [83] • Flag of West Virginia.svg  West Virginia [84]
July 9, 2022Flag of Kansas.svg  Kansas [85]
July 11, 2022Flag of New Mexico.svg  New Mexico [86]
July 12, 2022Flag of Delaware.svg  Delaware [87] • Flag of Arizona.svg  Arizona [88]
July 14, 2022Flag of South Dakota.svg  South Dakota [89]
July 15, 2022Flag of Alabama.svg  Alabama [90]
July 20, 2022Flag of North Dakota.svg  North Dakota [91]
July 22, 2022Flag of Maine.svg  Maine [92]
July 25, 2022Flag of Mississippi.svg  Mississippi [93]
July 29, 2022Flag of Alaska.svg  Alaska [94] • Flag of Vermont.svg  Vermont [95]
August 5, 2022Flag of Montana.svg  Montana [96]
August 22, 2022Flag of Wyoming.svg  Wyoming [97]

Timeline of first deaths by state

As of May 8, 2023 there have been 42 mpox-related deaths reported in the US. [46]

First confirmed mpox deaths by state
DateStates
August 30, 2022Flag of Texas.svg  Texas [98]
September 13, 2022Flag of California.svg  California [99]

Responses

Vaccination

On May 19, 2022, Bavarian Nordic announced that BARDA, part of the Department of Health and Human Services (HHS), exercised a $119 million option, under a $299 million contract, to supply a freeze-dried version of JYNNEOS vaccine, converting existing bulk vaccine. [100] The United States spent $119 million to purchase doses of the Modified vaccinia Ankara-based two-shot [101] Jynneos vaccine from Bavarian Nordic in May 2022. [102] The contract also allows the United States to purchase an additional $180 million worth of the vaccine at a later date. [103] The vaccine, JYNNEOS (also known by the brand names Imvamune and Imvanex), was approved by FDA in 2019 to prevent both smallpox and mpox. As of June 14, the United States had around 70,000 doses of JYNNEOS in its stockpile, and the federal government placed an order for 500,000 more on June 10, 2022. Dawn O'Connell, assistant secretary for preparedness and response at Department of Health and Human Services (HHS), said around 300,000 doses would be delivered in June–July 2022, and the remainder would be delivered later in that year. [17] [104]

In addition, the Strategic National Stockpile (SNS) holds over 100 million doses of an older smallpox vaccine (ACAM2000). [105]

As of June 28, the Biden administration was allocating tens of thousands of vaccine doses from the Strategic National Stockpile to clinics nation-wide. [106] [107] The rollout of vaccines and testing was criticized as too slow, as well as for having similar problems to the rollout of vaccines and tests during the COVID-19 pandemic in the United States. [108]

The United States government's response is coordinated by the National Security Council Directorate on Global Health Security and Biodefense – more commonly known as the White House Pandemic Office – in collaboration with the Department of Health and Human Services (HHS). The White House Pandemic Office had previously reinstated Dr. Beth Cameron to the executive position. [109] [110] The HHS is overseen by Secretary of Health and Human Services Xavier Becerra.

As of June 29, HHS has received requests from 32 states and jurisdictions, deploying over 9,000 doses of JYNNEOS vaccine and 300 courses of ST-246 (tecovirimat) [111] [112] antiviral smallpox treatments. [113] The United States expanded deployment of JYNNEOS vaccines, allocating 296,000 [114] [115] doses over the coming weeks, 56,000 of which will be allocated immediately. Over the coming months a combined 2.5 million [116] [117] [101] additional doses will become available. [118] As of November 2022, New York state ended its state of emergency, mobile mass vaccination sites set up since summer in New York city closed, but vaccinations were moved to outpatient and sexual health clinics. [119]

Precautionary measures

Hospitals have begun making their own preparations to help control the current mpox outbreak, including screening patients, increasing decontamination and cleaning procedures, [120] [121] [122] and wearing appropriate safety gear [123] [124] when interacting with infected patients.

See also

Notes

  1. ↑ This is the increase in cases over the previous day.
  2. ↑ This is the increase in cases from September 23rd, 2022, to January 4th, 2023 .

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The 2022–2023 mpox outbreak in Canada is a part of the outbreak of human mpox caused by the West African clade of the monkeypox virus. The outbreak started in Canada on May 19, 2022, with the country since then becoming one of the most affected in the Americas.

The 2022–2023 mpox outbreak in Belgium is part of the larger outbreak of human mpox caused by the West African clade of the monkeypox virus. Belgium was the fifth country, outside of the African countries with endemic mpox, to experience an outbreak in 2022. The first case was documented in Antwerp, Belgium, on 19 May 2022. As of 10 August, Belgium has 546 cases and 1 suspected case.

The 2022–2023 mpox outbreak in Australia is a part of the outbreak of human mpox caused by the West African clade of the monkeypox virus. The outbreak reached Australia on 20 May 2022. By 28 October 2022 there were over 140 confirmed cases. The Chief Medical Officer of Australia stood down the country's Communicable Disease Incident of National Significance declaration on 25 November 2022.

The 2022–2023 mpox outbreak in Israel is a part of the ongoing outbreak of human mpox caused by the West African clade of the monkeypox virus. The outbreak was first reported in Israel on 20 May 2022 when the Health Ministry announced a suspected case which was confirmed on 21 May 2022. One month later, on 21 June, the first locally transmitted case was reported.

The 2022–2023 mpox outbreak in Germany is part of an ongoing global outbreak of human mpox caused by the West African clade of the monkeypox virus. At the beginning of September 2022, Spain, France, Germany and the United Kingdom are the countries with most cumulative cases in Europe.

The 2022–2023 mpox outbreak in Switzerland is a part of the outbreak of human mpox caused by the West African clade of the monkeypox virus. The outbreak started in Switzerland on 19 May 2022, with the country since then becoming one of the most affected in Europe.

<span class="mw-page-title-main">Timeline of the 2022–2023 mpox outbreak</span> Major events in the 2022 monkeypox outbreak

This article documents the chronology and epidemiology of the 2022–2023 mpox outbreak.

<span class="mw-page-title-main">2022–2023 mpox outbreak in Brazil</span> Ongoing outbreak of mpox in Brazil

The 2022–2023 mpox outbreak in Brazil is a part of the ongoing outbreak of human mpox caused by the West African clade of the monkeypox virus. The outbreak was first reported in Brazil on 9 June 2022 when a man in São Paulo was registered as the country's index case.

<span class="mw-page-title-main">2022–2023 mpox outbreak in India</span> Ongoing outbreak of mpox in India

The 2022–2023 mpox outbreak in India is a part of the ongoing outbreak of human mpox caused by the West African clade of the monkeypox virus. The outbreak was first reported in India on 14 July 2022 when Kerala's State Health Minister Veena George announced a suspected imported case which was confirmed hours later by the NIV. India was the tenth country to report a mpox case in Asia and the first in South Asia. Currently, India has reported more than 30 cases of mpox.

<span class="mw-page-title-main">2022–2023 mpox outbreak in Spain</span> 2022–2023 outbreak of viral disease in Spain

The 2022–2023 mpox outbreak in Spain is a part of the outbreak of human mpox caused by the West African clade of the monkeypox virus. Spain was the second country outside the African countries with endemic mpox, to experience an outbreak in 2022. The outbreak was first reported in Spain on 18 May 2022.

<span class="mw-page-title-main">2022–2023 mpox outbreak in Asia</span> Ongoing outbreak of mpox in Asia

The 2022 mpox outbreak in Asia is a part of the ongoing outbreak of human mpox caused by the West African clade of the monkeypox virus. The outbreak was reported in Asia on 20 May 2022 when Israel reported a suspected case of mpox, which was confirmed on 21 May. As of 10 August 2022, seven West Asian, three Southeast Asian, three East Asian and one South Asian country, along with Russia, have reported confirmed cases.

The 2022–2023 mpox outbreak in Taiwan is a part of the larger outbreak of human mpox caused by the West African clade of the monkeypox virus. According to the Centers for Disease Control, Taiwan's first mpox case was reported on 24 June 2022.

The 2022–2023 mpox outbreak in North America is a part of the outbreak of human mpox caused by the West African clade of the monkeypox virus. The outbreak reached North America on 18 May 2022, when the United States reported their first case of mpox. As of 23 August 2022, 20 North American countries and territories have confirmed cases.

<span class="mw-page-title-main">2023–2024 mpox epidemic</span> Global disease outbreak since September 2023

An epidemic of a new variant of clade I mpox, called clade 1b, began in Central Africa at least as early as September 2023. As of September 2024, more than 29,000 cases have been reported, with over 800 fatalities, nearly all in the Democratic Republic of the Congo. According to the European CDC: "The size of these outbreaks could be larger than reported due to under-ascertainment and under-reporting."

The 2022–2024 mpox outbreak in New Zealand is a part of the outbreak of human mpox caused by the West African clade of the monkeypox virus. The outbreak reached New Zealand on 9 July 2022. By 15 August 2024, there had been 53 local cases of confirmed mpox in New Zealand since July 2022; with four occurring in Auckland in 2024. In mid-September 2024, a local outbreak linked to the Queenstown Winter Pride festival in late August 2024 had been reported.

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