3-methyleneoxindole reductase

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3-methyleneoxindole reductase
Identifiers
EC no. 1.3.1.17
CAS no. 37255-29-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, 3-methyleneoxindole reductase (EC 1.3.1.17) is an enzyme that catalyzes the chemical reaction

 
 
 
H+
3-methyleneoxindole reductase
 
H+
 
 

The two substrates of this enzyme are 3-methyloxindole and oxidised nicotinamide adenine dinucleotide phosphate (NADP+). Its products are 3-methyleneoxindole, reduced NADPH, and a proton. [1] [2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-methyl-1,3-dihydroindol-2-one:NADP+ oxidoreductase. This enzyme is also termed 3-methyloxindole:NADP+ oxidoreductase.

References

  1. Enzyme 1.3.1.17 at KEGG Pathway Database.
  2. Moyed HS, Williamson V (1967). "Multiple 3-methyleneoxindole reductases of peas, differential inhibition by synthetic auxins". J. Biol. Chem. 242 (5): 1075–7. doi: 10.1016/S0021-9258(18)96236-8 . PMID   6021071.