6-hydroxynicotinate reductase

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6-hydroxynicotinate reductase
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EC no. 1.3.7.1
CAS no. 9030-84-6
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In enzymology, a 6-hydroxynicotinate reductase (EC 1.3.7.1) is an enzyme that catalyzes the chemical reaction

6-oxo-1,4,5,6-tetrahydronicotinate + oxidized ferredoxin 6-hydroxynicotinate + reduced ferredoxin

Thus, the two substrates of this enzyme are 6-oxo-1,4,5,6-tetrahydronicotinate and oxidized ferredoxin, whereas its two products are 6-hydroxynicotinate and reduced ferredoxin.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is 6-oxo-1,4,5,6-tetrahydronicotinate:ferredoxin oxidoreductase. Other names in common use include 6-oxotetrahydronicotinate dehydrogenase, 6-hydroxynicotinic reductase, HNA reductase, and 1,4,5,6-tetrahydro-6-oxonicotinate:ferredoxin oxidoreductase.

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References


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