Highway 13 is an east–west highway through central Alberta. It runs from Alder Flats, 7 km (4 mi) west of Highway 22, to the Alberta-Saskatchewan border, where it becomes Saskatchewan Highway 14. Highway 13 is about 366 kilometres (227 mi) long. East of the City of Wetaskiwin, it generally parallels the Canadian Pacific Kansas City Prairie North Line.
Highway 9 is a highway in south-central Alberta, Canada, which together with Saskatchewan Highway 7 connects Calgary to Saskatoon, Saskatchewan via Drumheller. It is designated as a core route of the National Highway System, forming a portion of an interprovincial corridor. Highway 9 spans approximately 324 km (201 mi) from the Trans-Canada Highway east of Calgary to Alberta's border with Saskatchewan.
Highway 17 is a highway in Canada that straddles and criss-crosses the Alberta–Saskatchewan provincial border. The portion from the provincial border at Dillberry Lake Provincial Park to the provincial border 800 metres (2,600 ft) north of the North Saskatchewan River is designated as Alberta Provincial Highway No. 17 by Alberta Transportation, commonly referred to as Highway 17.
Highway 18 is a 161-kilometre (100 mi) highway in Alberta, Canada. It stretches from Highway 43 at the hamlet of Green Court, through the towns of Barrhead and Westlock, to Highway 63 east of the hamlet of Thorhild.
Highway 19 and Highway 625 are two provincial highways south of Edmonton in the Canadian province of Alberta that form a continuous east–west route connecting Highway 60 near Devon to Highway 21 east of Beaumont. Highway 19 was acquired by the City of Edmonton in the land annexation approved by the Province in 2019. Highway 19 passes north of the Edmonton International Airport and, in tandem with Highway 60, provides a southwest bypass of Edmonton between Highways 2 and 16. East of Highway 2, Highway 19 becomes Highway 625 and continues through Nisku Industrial Park. It intersects Highway 814 in Beaumont before ending at Highway 21.
Alberta Provincial Highway No. 27, commonly referred to as Highway 27, is a 151-kilometre (94 mi) east-west highway in central Alberta, Canada. It extends from Highway 22 in Sundre, through Olds along 46 Street, and intersects Highway 2 6 km (3.7 mi) east of Olds. It continues east where it intersects Highway 21 4 km (2.5 mi) south of Trochu where it branches south, passes Three Hills, and branches east 10 km (6.2 mi) to the south. The highway ends at intersection of Highways 9 and 56, 5 km (3.1 mi) east of Morrin and 21 km (13 mi) north of Drumheller.
Alberta Provincial Highway No. 32, commonly referred to as Highway 32, is a north–south highway in west–central Alberta, Canada. From north to south, Highway 32 begins at its junction with Highway 33 in the Town of Swan Hills. It proceeds south for 69 km (43 mi) where it meets Highway 43 northwest of Whitecourt. After following Highway 43 southeast for 8 km (5.0 mi), Highway 32 continues south from Whitecourt for 72 km (45 mi), crossing the McLeod River, passing through the Hamlet of Peers, and ending at Highway 16 approximately 32 km (20 mi) east of the Town of Edson.
Alberta Provincial Highway No. 38, commonly referred to as Highway 38, is a 25 km (16 mi) east–west highway in central Alberta, Canada. It extends from Highway 28 in Redwater to a 'T' junction with Highway 45 north of Bruderheim.
Alberta Provincial Highway No. 39, commonly referred to as Highway 39, is an east–west highway in central Alberta, Canada. It extends from Highway 22, approximately 13 kilometres (8 mi) east of Drayton Valley, to Leduc where it ends at Highway 2. Highway 39 is about 91 kilometres (57 mi) long.
Alberta Provincial Highway No. 50 is a 14.5 km (9.0 mi) east–west highway in central Alberta, Canada. It runs between the hamlets of Tees and Mirror, northeast of Red Deer.
Alberta Provincial Highway No. 52, commonly referred to as Highway 52, is an east–west highway in southern Alberta, Canada, south of Lethbridge that connects Highway 4 to Highway 5 via Raymond.
Alberta Provincial Highway No. 61, commonly referred to as Highway 61, is an east–west highway in southern Alberta, Canada. In the west, Highway 61 starts at Highway 4 north of the Village of Stirling and ends at Highway 889 east of the Hamlet of Manyberries. It is part of the Red Coat Trail, a historical route north of the Canada–US border. The Red Coat Trail continues to Saskatchewan via Highway 889 and Highway 501.
Alberta Provincial Highway No. 66, commonly referred to as Highway 66, is an east–west highway in central Alberta, Canada. In the east, Highway 66 begins at an intersection with Highways 22 and 762 south of the Hamlet of Bragg Creek and ends 28 km (17 mi) to the west at the Little Elbow Recreation Area. The highway provides access to the Easter Seals Camp Horizon and Elbow Falls.
Alberta Provincial Highway No. 59, commonly referred to as Highway 59, is an east–west highway in northwest Alberta, Canada. It runs from Highway 2 north of Sexsmith to Highway 43 northwest of Hythe.
Alberta Provincial Highway No. 55, commonly referred to as Highway 55, is a 263-kilometre (163 mi) long east–west highway in northeast Alberta, Canada. It extends from the Saskatchewan border in the east through the Cold Lake, Lac La Biche, and Athabasca where it ends at Highway 2. In Saskatchewan, it continues as Saskatchewan Highway 55.
Alberta Provincial Highway No. 49, commonly referred to as Highway 49, is a highway in northwestern Alberta, Canada. It runs east–west from the British Columbia border to Donnelly, and then north–south to Valleyview. Highway 49 has a total length of 266 kilometres (165 mi).
Alberta Provincial Highway No. 64 is an east-west highway in northern Alberta, Canada. In the west, Highway 64 begins at the Alberta/British Columbia border and ends at Highway 2 southwest of the Town of Fairview.
Alberta Provincial Highway No. 53, commonly referred to as Highway 53, is an east–west highway of approximately 222 km (138 mi) in central Alberta, Canada.
Wye Road is a major arterial road and rural highway that links Sherwood Park from Anthony Henday Drive on the east side of Edmonton to Highway 14 west of Tofield. It is preceded by Sherwood Park Freeway, and east of Highway 21 is designated as Alberta Provincial Highway No. 630, commonly referred to as Highway 630. Wye Road is part of a 40-kilometre-long (25 mi) continuous roadway that runs through Sherwood Park, Edmonton, and St. Albert that includes Sherwood Park Freeway, Whyte Avenue, portions of University Avenue and Saskatchewan Drive, Groat Road, and St. Albert Trail.
Highway 15 south of Bruderheim 
Highway 3 at Saskatchewan border
