Arsenophonus

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Arsenophonus
Scientific classification OOjs UI icon edit-ltr.svg
Domain: Bacteria
Kingdom: Pseudomonadati
Phylum: Pseudomonadota
Class: Gammaproteobacteria
Order: Enterobacterales
Family: Morganellaceae
Genus: Arsenophonus
Gherna et al. 1991
Type species
Arsenophonus nasoniae [1]
Species [1]

Arsenophonus is a genus of Morganellaceae, of the Gammaproteobacteria. [2] Members of the Arsenophonus genus are increasingly discovered bacterial symbionts of arthropods that are estimated to infect over 5% of arthropod species globally [3] and form a variety of relationships with hosts across the mutualism parasitism continuum. Arsenophonus bacteria have been identified in a diversity of insect taxa, including economically important species such as the Western honey bee [4] [5] and the rice pest Nilaparvata lugens . [6]

Contents

The majority of work on Arsenophonus has been done on the type species Arsenophonus nasoniae for which genetic manipulation has been successful in achieving in vivo tracking of the bacterium. [7] Arsenophonus nasoniae infects Nasonia parasitic wasps, [8] [1] is vertically transmitted, passed from a female wasp to the fly host during parasitisation, and then acquired by her hatching larvae feeding on the microbe. [9] It has a male-killing phenotype. Infection with Arsenophonus nasoniae triggers the death of approximately 80% of the wasps male offspring. [10] [11] Killing male offspring is thought to facilitate the spread of Arsenophonus through the host population as it releases more resources to female offspring, and it is the female line that Arsenophonus is transmitted through. [12] [13] However, horizontal transmission during superparasitism of a single fly pupae by multiple wasp females is required for symbiont spread. [14]

Within the genus a number of Arsenophonus strains have known roles as mutualistic endosymbionts. [15] In both Pediculus humanus [16] and Lipoptena cervi [17] Arsenophonus symbionts are essential to host functioning and are involved in vitamin synthesis, and are vertically transmitted across host generations. In other hosts Arsenophonus is suspected to be parasitic and infection acquired through the environment. In the Western honey bee Arsenophonus can be horizontally transmitted via social behaviour, [5] and the presence of Arsenophonus in a colony has been linked to poor bee health. [18] [19] This species has been formally described as Arsenophonus apicola. [20] Arsenophonus apicola can also infect Galleria mellonella waxworms both through injection and orally, indicating it can also develop associations with honey bee associated taxa. [21] The majority of associations between Arsenophonus and host taxa remain uncharacterized.

The diversity of interactions between Arsenophonus and insects has led to the genus being adopted, alongside Sodalis , as one where it is possible to investigate the genetic and evolutionary changes associated with different types of symbiosis. Siozios et al [22] demonstrated early stages of transition to vertical (parent-offspring) transmission were associated with increases in Arsenophonus genome size, associated with proliferation of prophage. This was considered a consequence of loss of CRISPR-Cas defences, hypothesized to be driven by reduce phage predation rates in strongly host associated endosymbionts. Indeed, Arsenophonus nasoniae has one of the more complex microbial genomes, carrying over 50 prophage elements and 17 plasmids. [23]

References

  1. 1 2 3 LPSN lpsn.dsmz.de
  2. Gherna, Robert L.; et al. (1991). "NOTES: Arsenophonus nasoniae gen. nov., sp. nov., the Causative Agent of the Son-Killer Trait in the Parasitic Wasp Nasonia vitripennis". International Journal of Systematic Bacteriology. 41 (4): 563–565. doi: 10.1099/00207713-41-4-563 .
  3. Duron, Olivier; Bouchon, Didier; Boutin, Sébastien; Bellamy, Lawrence; Zhou, Liqin; Engelstädter, Jan; Hurst, Gregory D. (2008-06-24). "The diversity of reproductive parasites among arthropods: Wolbachiado not walk alone". BMC Biology. 6 (1): 27. doi: 10.1186/1741-7007-6-27 . ISSN   1741-7007. PMC   2492848 . PMID   18577218.
  4. Yañez, Orlando (2016). "Endosymbiotic bacteria in honey bees: Arsenophonus spp. are not transmitted transovarially". FEMS Microbiology Letters. 363 (14): fnw147. doi:10.1093/femsle/fnw147. PMC   4941583 . PMID   27279628.
  5. 1 2 Drew, Georgia C.; Budge, Giles E.; Frost, Crystal L.; Neumann, Peter; Siozios, Stefanos; Yañez, Orlando; Hurst, Gregory D. D. (October 2021). "Transitions in symbiosis: evidence for environmental acquisition and social transmission within a clade of heritable symbionts". The ISME Journal. 15 (10): 2956–2968. Bibcode:2021ISMEJ..15.2956D. doi:10.1038/s41396-021-00977-z. ISSN   1751-7370. PMC   8443716 . PMID   33941888.
  6. Fan, Hai-Wei; Lu, Jia-Bao; Ye, Yu-Xuan; Yu, Xiao-Ping; Zhang, Chuan-Xi (2016). "Characteristics of the draft genome of "Candidatus Arsenophonus nilaparvatae", a facultative endosymbiont of Nilaparvata lugens" . Insect Science. 23 (3): 478–486. Bibcode:2016InsSc..23..478F. doi:10.1111/1744-7917.12318. ISSN   1744-7917. PMID   26792263. S2CID   44398605.
  7. Nadal-Jimenez, Pol; Griffin, Joanne S.; Davies, Lianne; Frost, Crystal L.; Marcello, Marco; Hurst, Gregory D. D. (2019). "Genetic manipulation allows in vivo tracking of the life cycle of the son-killer symbiont, Arsenophonus nasoniae, and reveals patterns of host invasion, tropism and pathology". Environmental Microbiology. 21 (8): 3172–3182. Bibcode:2019EnvMi..21.3172N. doi:10.1111/1462-2920.14724. ISSN   1462-2920. PMC   6771839 . PMID   31237728.
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  11. Ferree, Patrick M.; Avery, Amanda; Azpurua, Jorge; Wilkes, Timothy; Werren, John H. (2008-09-23). "A Bacterium Targets Maternally Inherited Centrosomes to Kill Males in Nasonia". Current Biology. 18 (18): 1409–1414. Bibcode:2008CBio...18.1409F. doi:10.1016/j.cub.2008.07.093. ISSN   0960-9822. PMC   2577321 . PMID   18804376.
  12. Engelstädter, Jan; Hurst, Gregory D. D. (January 2007). "The Impact of Male-Killing Bacteria on Host Evolutionary Processes". Genetics. 175 (1): 245–254. doi:10.1534/genetics.106.060921. ISSN   0016-6731. PMC   1774985 . PMID   17151259.
  13. Hurst, Gregory D. D.; Majerus, Michael E. N. (July 1993). "Why do maternally inherited microorganisms kill males?". Heredity. 71 (1): 81–95. doi: 10.1038/hdy.1993.110 . ISSN   1365-2540. S2CID   26129786.
  14. Parratt, Steven R.; Frost, Crystal L.; Schenkel, Martijn A.; Rice, Annabel; Hurst, Gregory D. D.; King, Kayla C. (20 June 2016). "Superparasitism Drives Heritable Symbiont Epidemiology and Host Sex Ratio in a Wasp". PLOS Pathogens. 12 (6): e1005629. doi: 10.1371/journal.ppat.1005629 . PMC   4920596 . PMID   27322651.
  15. Nováková, E.; Hypša, V.; Moran, A. (2009). "Arsenophonus, an emerging clade of intracellular symbionts with a broad host distribution". BMC Microbiology. 9: 143. doi: 10.1186/1471-2180-9-143 . PMC   2724383 . PMID   19619300.
  16. Perotti, M. Alejandra; Allen, Julie M.; Reed, David L.; Braig, Henk R. (April 2007). "Host-symbiont interactions of the primary endosymbiont of human head and body lice". FASEB Journal. 21 (4): 1058–1066. doi: 10.1096/fj.06-6808com . ISSN   1530-6860. PMID   17227954. S2CID   18998241.
  17. Nováková, Eva; Hypša, Václav; Nguyen, Petr; Husník, Filip; Darby, Alistair C. (2016-09-17). "Genome sequence of Candidatus Arsenophonus lipopteni, the exclusive symbiont of a blood sucking fly Lipoptena cervi (Diptera: Hippoboscidae)". Standards in Genomic Sciences. 11 (1): 72. Bibcode:2016SGenS..11...72N. doi: 10.1186/s40793-016-0195-1 . ISSN   1944-3277. PMC   5027103 . PMID   27660670.
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Further reading