Equivalent dose

Last updated
equivalent dose
Common symbols
H
SI unit sievert
Other units
röntgen equivalent man
In SI base units J kg −1

Equivalent dose is a dose quantity H representing the stochastic health effects of low levels of ionizing radiation on the human body which represents the probability of radiation-induced cancer and genetic damage. It is derived from the physical quantity absorbed dose, but also takes into account the biological effectiveness of the radiation, which is dependent on the radiation type and energy. In the SI system of units, the unit of measure is the sievert (Sv).

Contents

Application

External dose quantities used in radiation protection and dosimetry Dose quantities and units.png
External dose quantities used in radiation protection and dosimetry

To enable consideration of stochastic health risk, calculations are performed to convert the physical quantity absorbed dose into equivalent dose, the details of which depend on the radiation type. For applications in radiation protection and dosimetry assessment, the International Commission on Radiological Protection (ICRP) and the International Commission on Radiation Units and Measurements (ICRU) have published recommendations and data on how to calculate equivalent dose from absorbed dose.

Equivalent dose is designated by the ICRP as a "limiting quantity"; to specify exposure limits to ensure that "the occurrence of stochastic health effects is kept below unacceptable levels and that tissue reactions are avoided". [1] [2] [3] This is a calculated value, as equivalent dose cannot be practically measured, and the purpose of the calculation is to generate a value of equivalent dose for comparison with observed health effects. [4]

Calculation

Relationships of SI external "protection" dose quantities SI Radiation dose units.png
Relationships of SI external "protection" dose quantities

Equivalent dose HT is calculated using the mean absorbed dose deposited in body tissue or organ T, multiplied by the radiation weighting factor WR which is dependent on the type and energy of the radiation R.

The radiation weighting factor represents the relative biological effectiveness of the radiation and modifies the absorbed dose to take account of the different biological effects of various types and energies of radiation.

The ICRP has assigned radiation weighting factors to specified radiation types dependent on their relative biological effectiveness, which are shown in accompanying table. [5]

Calculating equivalent dose from absorbed dose;

where

HT  is the equivalent dose in sieverts (Sv) absorbed by tissue T,
DT,R  is the absorbed dose in grays (Gy) in tissue T by radiation type R and
WR  is the radiation weighting factor defined by regulation.

Thus for example, an absorbed dose of 1 Gy by alpha particles will lead to an equivalent dose of 20 Sv, and an equivalent dose of radiation is estimated to have the same biological effect as an equal amount of absorbed dose of gamma rays, which is given a weighting factor of 1.

To obtain the equivalent dose for a mix of radiation types and energies, a sum is taken over all types of radiation energy doses. [6] This takes into account the contributions of the varying biological effect of different radiation types.

Radiation weighting factors WR (formerly termed Q factor)
used to represent relative biological effectiveness
according to ICRP report 103 [6]
RadiationEnergyWR (formerly Q)
x-rays, gamma rays,
beta particles, muons
 1
neutrons < 1 MeV2.5 + 18.2·e−[ln(E)]²/6
1...50 MeV5.0 + 17.0·e−[ln(2·E)]²/6
> 50 MeV2.5 + 3.25·e−[ln(0.04·E)]²/6
protons, charged pions  2
alpha particles, fission
products
, heavy nuclei
 20

History

The concept of equivalent dose was developed in the 1950s. [7] In its 1990 recommendations, the ICRP revised the definitions of some radiation protection quantities, and provided new names for the revised quantities. [8] Some regulators, notably the International Committee for Weights and Measures (CIPM) and the US Nuclear Regulatory Commission continue to use the old terminology of quality factors and dose equivalent, even though the underlying calculations have changed. [9]

Future use

At the ICRP 3rd International Symposium on the System of Radiological Protection in October 2015, ICRP Task Group 79 reported on the "Use of Effective Dose as a Risk-related Radiological Protection Quantity".

This included a proposal to discontinue use of equivalent dose as a separate protection quantity. This would avoid confusion between equivalent dose, effective dose and dose equivalent, and to use absorbed dose in Gy as a more appropriate quantity for limiting deterministic effects to the eye lens, skin, hands & feet. [10]

These proposals will need to go through the following stages:

Units

The SI unit of measure for equivalent dose is the sievert, defined as one Joule per kg. [11] In the United States the roentgen equivalent man (rem), equal to 0.01 sievert, is still in common use, although regulatory and advisory bodies are encouraging transition to sievert. [12]

Limitation of equivalent dose calculation

Equivalent dose HT is used for assessing stochastic health risk due to external radiation fields that penetrate uniformly through the whole body. However it needs further corrections when the field is applied only to part(s) of the body, or non-uniformly to measure the overall stochastic health risk to the body. To enable this a further dose quantity called effective dose must be used to take into account the varying sensitivity of different organs and tissues to radiation.

Relationship to committed dose

Whilst equivalent dose is used for the stochastic effects of external radiation, a similar approach is used for internal, or committed dose. The ICRP defines an equivalent dose quantity for individual committed dose, which is used to measure the effect of inhaled or ingested radioactive materials. A committed dose from an internal source represents the same effective risk as the same amount of equivalent dose applied uniformly to the whole body from an external source.

Committed equivalent dose, H T(t) is the time integral of the equivalent dose rate in a particular tissue or organ that will be received by an individual following intake of radioactive material into the body by a Reference Person, where s is the integration time in years. [13] This refers specifically to the dose in a specific tissue or organ, in the similar way to external equivalent dose.

The ICRP states "Radionuclides incorporated in the human body irradiate the tissues over time periods determined by their physical half-life and their biological retention within the body. Thus they may give rise to doses to body tissues for many months or years after the intake. The need to regulate exposures to radionuclides and the accumulation of radiation dose over extended periods of time has led to the definition of committed dose quantities". [14]

Equivalent dose V dose equivalent

There is no confusion between equivalent dose and dose equivalent. Indeed, they are same concepts. Although the CIPM definition states that the linear energy transfer function of the ICRU is used in calculating the biological effect, the ICRP in 1990 [15] developed the "protection" dose quantities named effective and equivalent dose, which are calculated from more complex computational models and are distinguished by not having the phrase dose equivalent in their name.

Prior to 1990, the ICRP used the term "dose equivalent" to refer to the absorbed dose at a point multiplied by the quality factor at that point, where the quality factor was a function of linear energy transfer (LET). Currently, the ICRP's definition of "equivalent dose" represents an average dose over an organ or tissue, and radiation weighting factors are used instead of quality factors.

The phrase dose equivalent is only used for which use Q for calculation, and the following are defined as such by the ICRU and ICRP:

In the US there are further differently named dose quantities which are not part of the ICRP system of quantities. [16]

Use of old factors

The radiation weighting factor for neutrons has been revised over time, and is different for US NRC, and ICRP. Neutron radiation weighting factor as a function of kinetic energy.gif
The radiation weighting factor for neutrons has been revised over time, and is different for US NRC, and ICRP.

The International Committee for Weights and Measures (CIPM) and the US Nuclear Regulatory Commission continue to use the old terminology of quality factors and dose equivalent. The NRC quality factors are independent of linear energy transfer, though not always equal to the ICRP radiation weighting factors. [9] The NRC's definition of dose equivalent is "the product of the absorbed dose in tissue, quality factor, and all other necessary modifying factors at the location of interest." However, it is apparent from their definition of effective dose equivalent that "all other necessary modifying factors" excludes the tissue weighting factor. [17] The radiation weighting factors for neutrons are also different between US NRC and the ICRP - see accompanying diagram.

Dosimetry reports

Cumulative equivalent dose due to external whole-body exposure is normally reported to nuclear energy workers in regular dosimetry reports.

In the US, three different equivalent doses are typically reported:

See also

Related Research Articles

<span class="mw-page-title-main">Sievert</span> SI unit of equivalent dose of ionizing radiation

The sievert is a unit in the International System of Units (SI) intended to represent the stochastic health risk of ionizing radiation, which is defined as the probability of causing radiation-induced cancer and genetic damage. The sievert is important in dosimetry and radiation protection. It is named after Rolf Maximilian Sievert, a Swedish medical physicist renowned for work on radiation dose measurement and research into the biological effects of radiation.

The gray is the unit of ionizing radiation dose in the International System of Units (SI), defined as the absorption of one joule of radiation energy per kilogram of matter.

Radiation dosimetry in the fields of health physics and radiation protection is the measurement, calculation and assessment of the ionizing radiation dose absorbed by an object, usually the human body. This applies both internally, due to ingested or inhaled radioactive substances, or externally due to irradiation by sources of radiation.

Radiation protection, also known as radiological protection, is defined by the International Atomic Energy Agency (IAEA) as "The protection of people from harmful effects of exposure to ionizing radiation, and the means for achieving this". Exposure can be from a source of radiation external to the human body or due to internal irradiation caused by the ingestion of radioactive contamination.

<span class="mw-page-title-main">Health physics</span>

Health physics, also referred to as the science of radiation protection, is the profession devoted to protecting people and their environment from potential radiation hazards, while making it possible to enjoy the beneficial uses of radiation. Health physicists normally require a four-year bachelor’s degree and qualifying experience that demonstrates a professional knowledge of the theory and application of radiation protection principles and closely related sciences. Health physicists principally work at facilities where radionuclides or other sources of ionizing radiation are used or produced; these include research, industry, education, medical facilities, nuclear power, military, environmental protection, enforcement of government regulations, and decontamination and decommissioning—the combination of education and experience for health physicists depends on the specific field in which the health physicist is engaged.

The roentgen equivalent man (rem) is a CGS unit of equivalent dose, effective dose, and committed dose, which are dose measures used to estimate potential health effects of low levels of ionizing radiation on the human body.

Absorbed dose is a dose quantity which is the measure of the energy deposited in matter by ionizing radiation per unit mass. Absorbed dose is used in the calculation of dose uptake in living tissue in both radiation protection, and radiology. It is also used to directly compare the effect of radiation on inanimate matter such as in radiation hardening.

<span class="mw-page-title-main">Radioactive contamination</span> Undesirable radioactive elements on surfaces or in gases, liquids, or solids

Radioactive contamination, also called radiological pollution, is the deposition of, or presence of radioactive substances on surfaces or within solids, liquids, or gases, where their presence is unintended or undesirable.

The rad is a unit of absorbed radiation dose, defined as 1 rad = 0.01 Gy = 0.01 J/kg. It was originally defined in CGS units in 1953 as the dose causing 100 ergs of energy to be absorbed by one gram of matter. The material absorbing the radiation can be human tissue, air, water, or any other substance.

<span class="mw-page-title-main">Linear energy transfer</span>

In dosimetry, linear energy transfer (LET) is the amount of energy that an ionizing particle transfers to the material traversed per unit distance. It describes the action of radiation into matter.

The International Commission on Radiological Protection (ICRP) is an independent, international, non-governmental organization, with the mission to protect people, animals, and the environment from the harmful effects of ionising radiation. Its recommendations form the basis of radiological protection policy, regulations, guidelines and practice worldwide.

The International Commission on Radiation Units and Measurements (ICRU) is a standardization body set up in 1925 by the International Congress of Radiology, originally as the X-Ray Unit Committee until 1950. Its objective "is to develop concepts, definitions and recommendations for the use of quantities and their units for ionizing radiation and its interaction with matter, in particular with respect to the biological effects induced by radiation".

Radiobiology is a field of clinical and basic medical sciences that involves the study of the effects of ionizing radiation on living things, in particular health effects of radiation. Ionizing radiation is generally harmful and potentially lethal to living things but can have health benefits in radiation therapy for the treatment of cancer and thyrotoxicosis. Its most common impact is the induction of cancer with a latent period of years or decades after exposure. High doses can cause visually dramatic radiation burns, and/or rapid fatality through acute radiation syndrome. Controlled doses are used for medical imaging and radiotherapy.

In radiobiology, the relative biological effectiveness is the ratio of biological effectiveness of one type of ionizing radiation relative to another, given the same amount of absorbed energy. The RBE is an empirical value that varies depending on the type of ionizing radiation, the energies involved, the biological effects being considered such as cell death, and the oxygen tension of the tissues or so-called oxygen effect.

Committed dose equivalent and Committed effective dose equivalent are dose quantities used in the United States system of radiological protection for irradiation due to an internal source.

Internal dosimetry is the science and art of internal ionising radiation dose assessment due to radionuclides incorporated inside the human body.

<span class="mw-page-title-main">Roentgen (unit)</span> Measurement of radiation exposure

The roentgen or röntgen is a legacy unit of measurement for the exposure of X-rays and gamma rays, and is defined as the electric charge freed by such radiation in a specified volume of air divided by the mass of that air . In 1928, it was adopted as the first international measurement quantity for ionizing radiation to be defined for radiation protection, as it was then the most easily replicated method of measuring air ionization by using ion chambers. It is named after the German physicist Wilhelm Röntgen, who discovered X-rays and was awarded the first Nobel Prize in Physics for the discovery.

Effective dose is a dose quantity in the International Commission on Radiological Protection (ICRP) system of radiological protection.

The committed dose in radiological protection is a measure of the stochastic health risk due to an intake of radioactive material into the human body. Stochastic in this context is defined as the probability of cancer induction and genetic damage, due to low levels of radiation. The SI unit of measure is the sievert.

<span class="mw-page-title-main">Radiation exposure</span> Measure of ionization of air by ionizing radiation

Radiation exposure is a measure of the ionization of air due to ionizing radiation from photons. It is defined as the electric charge freed by such radiation in a specified volume of air divided by the mass of that air. As of 2007, "medical radiation exposure" was defined by the International Commission on Radiological Protection as exposure incurred by people as part of their own medical or dental diagnosis or treatment; by persons, other than those occupationally exposed, knowingly, while voluntarily helping in the support and comfort of patients; and by volunteers in a programme of biomedical research involving their exposure. Common medical tests and treatments involving radiation include X-rays, CT scans, mammography, lung ventilation and perfusion scans, bone scans, cardiac perfusion scan, angiography, radiation therapy, and more. Each type of test carries its own amount of radiation exposure. There are two general categories of adverse health effects caused by radiation exposure: deterministic effects and stochastic effects. Deterministic effects are due to the killing/malfunction of cells following high doses; and stochastic effects involve either cancer development in exposed individuals caused by mutation of somatic cells, or heritable disease in their offspring from mutation of reproductive (germ) cells.

References

  1. ICRP publication 103, paragraph 112
  2. ICRP publication 103, paragraph B50
  3. "In 1991, the International Commission on Radiological Protection (ICRP) [7] recommended a revised system of dose limitation, including specification of primary limiting quantities for radiation protection purposes. These protection quantities are essentially unmeasurable" - IAEA Safety report 16
  4. ICRP publication 103, paragraph B64
  5. ICRP publication 103, glossary
  6. 1 2 "The 2007 Recommendations of the International Commission on Radiological Protection". Annals of the ICRP. ICRP publication 103. 37 (2–4). 2007. ISBN   978-0-7020-3048-2. Archived from the original on 16 November 2012. Retrieved 17 May 2012.
  7. Clarke, R.H.; J. Valentin (2009). "The History of ICRP and the Evolution of its Policies" (PDF). Annals of the ICRP. ICRP Publication 109. 39 (1): 75–110. doi:10.1016/j.icrp.2009.07.009. S2CID   71278114 . Retrieved 12 May 2012.
  8. Vennart, J. (1991). "1990 Recommendations of the International Commission on Radiological Protection" . Annals of the ICRP. ICRP publication 60. 21 (1–3): 199. Bibcode:1991JRP....11..199V. doi:10.1088/0952-4746/11/3/006. ISBN   978-0-08-041144-6. S2CID   250822587 . Retrieved 17 May 2012.
  9. 1 2 10 CFR 20.1004. US Nuclear Regulatory Commission. 2009.
  10. "Use of Effective Dose", John Harrison. 3rd International Symposium on the System of Radiological Protection, October 2015, Seoul.
  11. Le Système international d’unités [The International System of Units](PDF) (in French and English) (9th ed.), International Bureau of Weights and Measures, 2019, ISBN   978-92-822-2272-0
  12. Nuclear Regulatory Commission. "NRC Regulations: §34.3 Definitions". United States Government. Retrieved 2007-03-14.
  13. ICRP publication 103 - Glossary.
  14. ICRP Publication 103 paragraph 140
  15. ICRP publication 60 published in 1991
  16. - "The confusing world of radiation dosimetry" Archived 2016-12-21 at the Wayback Machine - M.A. Boyd, U.S. Environmental Protection Agency 2009. An account of chronological differences between US and ICRP dosimetry systems.
  17. 10 CFR 20.1003. US Nuclear Regulatory Commission. 2009.