FGD4

Last updated
FGD4
Identifiers
Aliases FGD4 , CMT4H, FRABP, ZFYVE6, FYVE, RhoGEF and PH domain containing 4
External IDs OMIM: 611104; MGI: 2183747; HomoloGene: 26727; GeneCards: FGD4; OMA:FGD4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001301817
NM_001301818
NM_139232
NM_139233
NM_139234

RefSeq (protein)

NP_001288746
NP_001288747
NP_631978

Location (UCSC) Chr 12: 32.4 – 32.65 Mb Chr 16: 16.23 – 16.42 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

FYVE, RhoGEF and PH domain-containing protein 4 is a protein encoded in humans by the FGD4 gene. [5] [6]

See also

Related Research Articles

<span class="mw-page-title-main">FGD1</span> Protein-coding gene in the species Homo sapiens

FYVE, RhoGEF and PH domain-containing protein 1 (FGD1) also known as faciogenital dysplasia 1 protein (FGDY), zinc finger FYVE domain-containing protein 3 (ZFYVE3), or Rho/Rac guanine nucleotide exchange factor FGD1 is a protein that in humans is encoded by the FGD1 gene that lies on the X chromosome. Orthologs of the FGD1 gene are found in dog, cow, mouse, rat, and zebrafish, and also budding yeast and C. elegans. It is a member of the FYVE, RhoGEF and PH domain containing family.

<span class="mw-page-title-main">ARHGEF6</span> Protein-coding gene in humans

Rho guanine nucleotide exchange factor 6 is a protein that, in humans, is encoded by the ARHGEF6 gene.

<span class="mw-page-title-main">ARHGEF1</span> Protein-coding gene in the species Homo sapiens

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<span class="mw-page-title-main">ARHGEF12</span> Protein-coding gene in the species Homo sapiens

Rho guanine nucleotide exchange factor 12 is a protein that in humans is encoded by the ARHGEF12 gene. This protein is also called RhoGEF12 or Leukemia-associated Rho guanine nucleotide exchange factor (LARG).

<span class="mw-page-title-main">RhoG</span> Protein-coding gene in the species Homo sapiens

RhoG is a small monomeric GTP-binding protein, and is an important component of many intracellular signalling pathways. It is a member of the Rac subfamily of the Rho family of small G proteins and is encoded by the gene RHOG.

<span class="mw-page-title-main">TRIO (gene)</span> Protein-coding gene in the species Homo sapiens

Triple functional domain protein is a protein that in humans is encoded by the TRIO gene.

<span class="mw-page-title-main">PRX (gene)</span> Protein-coding gene in the species Homo sapiens

Periaxin is a protein that in humans is encoded by the PRX gene.

<span class="mw-page-title-main">SH3TC2</span> Protein-coding gene in the species Homo sapiens

SH3 domain and tetratricopeptide repeats-containing protein 2 is a protein that in humans is encoded by the SH3TC2 gene. It is believed to be expressed in the Schwann cells that wrap the myelin sheath around nerves.

<span class="mw-page-title-main">Dedicator of cytokinesis protein 7</span> Protein found in humans

Dedicator of cytokinesis protein (Dock7) is a large protein encoded in the human by the DOCK7 gene, involved in intracellular signalling networks. It is a member of the DOCK-C subfamily of the DOCK family of guanine nucleotide exchange factors (GEFs) which function as activators of small G-proteins. Dock7 activates isoforms of the small G protein Rac.

<span class="mw-page-title-main">DAAM1</span> Protein-coding gene in the species Homo sapiens

Dishevelled-associated activator of morphogenesis 1 is a protein that in humans is encoded by the DAAM1 gene. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.

<span class="mw-page-title-main">Dedicator of cytokinesis protein 10</span> Protein found in humans

Dedicator of cytokinesis protein 10 (Dock10), also known as Zizimin3, is a large protein involved in intracellular signalling networks that in humans is encoded by the DOCK10 gene. It is a member of the DOCK-D subfamily of the DOCK family of guanine nucleotide exchange factors, which function as activators of small G-proteins.

<span class="mw-page-title-main">FGD3</span> Protein-coding gene in the species Homo sapiens

FYVE, RhoGEF and PH domain-containing protein 3 is a protein that in humans is encoded by the FGD3 gene.

<span class="mw-page-title-main">Dedicator of cytokinesis protein 4</span> Protein found in humans

Dedicator of cytokinesis protein 4 (Dock4), is a large protein encoded in the human by the DOCK4 gene, involved in intracellular signalling networks. It is a member of the DOCK-B subfamily of the DOCK family of guanine nucleotide exchange factors (GEFs) which function as activators of small G-proteins. Dock4 activates the small G proteins Rac and Rap1.

<span class="mw-page-title-main">Dedicator of cytokinesis protein 9</span> Protein found in humans

Dedicator of cytokinesis protein 9 (Dock9), also known as Zizimin1, is a large protein encoded in the human by the DOCK9 gene, involved in intracellular signalling networks. It is a member of the DOCK-D subfamily of the DOCK family of guanine nucleotide exchange factors that function as activators of small G-proteins. Dock9 activates the small G protein Cdc42.

<span class="mw-page-title-main">ARHGEF4</span> Protein-coding gene in the species Homo sapiens

Rho guanine nucleotide exchange factor 4 is a protein that in humans is encoded by the ARHGEF4 gene.

<span class="mw-page-title-main">Dedicator of cytokinesis protein 6</span> Protein found in humans

Dedicator of cytokinesis protein 6 (Dock6), also known as Zir1 is a large protein encoded in the human by the DOCK6 gene, involved in intracellular signalling networks. It is a member of the DOCK-C subfamily of the DOCK family of guanine nucleotide exchange factors which function as activators of small G-proteins.

<span class="mw-page-title-main">Dedicator of cytokinesis protein 11</span> Protein-coding gene in humans

Dedicator of cytokinesis protein 11 (Dock11), also known as Zizimin2, is a large protein encoded in the human by the DOCK11 gene, involved in intracellular signalling networks. It is a member of the DOCK-D subfamily of the DOCK family of guanine nucleotide exchange factors (GEFs) which function as activators of small G-proteins. Dock11 activates the small G protein Cdc42.

<span class="mw-page-title-main">FGD2</span> Protein-coding gene in the species Homo sapiens

FYVE, RhoGEF and PH domain-containing protein 2 (FGD2), also known as zinc finger FYVE domain-containing protein 4 (ZFYVE4), is a protein that in humans is encoded by the FGD2 gene.

<span class="mw-page-title-main">ARHGAP31</span> Protein-coding gene in the species Homo sapiens

The Rho GTPase activating protein 31 is encoded in humans by the ARHGAP31 gene. It is a Cdc42/Rac1 GTPase regulator.

<span class="mw-page-title-main">PLEKHG2</span> Protein-coding gene in the species Homo sapiens

Pleckstrin homology domain containing, family G member 2 (PLEKHG2) is a protein that in humans is encoded by the PLEKHG2 gene. It is sometimes written as ARHGEF42, FLJ00018.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000139132 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022788 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Ikeda W, Nakanishi H, Takekuni K, Itoh S, Takai Y (Aug 2001). "Identification of splicing variants of Frabin with partly different functions and tissue distribution". Biochem Biophys Res Commun. 286 (5): 1066–72. doi:10.1006/bbrc.2001.5481. PMID   11527409.
  6. "Entrez Gene: FGD4 FYVE, RhoGEF and PH domain containing 4".

Further reading