Heparin-sulfate lyase

Last updated
heparin-sulfate lyase
Identifiers
EC no. 4.2.2.8
CAS no. 37290-86-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

The enzyme heparin-sulfate lyase (EC 4.2.2.8) catalyzes the chemical reaction

Elimination of sulfate; appears to act on linkages between N-acetyl-D-lucosamine and uronate. Product is an unsaturated sugar.

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is heparin-sulfate lyase. Other names in common use include heparin-sulfate eliminase, heparitin-sulfate lyase, heparitinase I, and heparitinase II.

References