3-Hydroxyacyl ACP dehydrase

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enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase
HydroxyacylACPdehydrase.png
The structure of (3R)-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Pseudomonas aeruginosa [1]
Identifiers
SymbolEHHADH
Alt. symbolsECHD
NCBI gene 1962
HGNC 3247
OMIM 607037
RefSeq NM_001966
UniProt Q08426
Other data
EC number 4.2.1.17
Locus Chr. 3 q26.3-q28
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Structures Swiss-model
Domains InterPro

3-Hydroxyacyl ACP dehydratase is an enzyme involved in fatty acid synthesis. In humans, it is encoded by the EHHADH gene. [2]

3-Hydroxyacyl ACP dehydrase reaction.svg

References

  1. ↑ "RCSB Protein Data Bank - Structure Summary for 1U1Z - The Structure of (3R)-hydroxyacyl-ACP dehydratase (FabZ)".
  2. ↑ Hoefler G, Forstner M, McGuinness MC, Hulla W, Hiden M, Krisper P, et al. (January 1994). "cDNA cloning of the human peroxisomal enoyl-CoA hydratase: 3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme and localization to chromosome 3q26.3-3q28: a free left Alu Arm is inserted in the 3' noncoding region". Genomics. 19 (1): 60–67. doi:10.1006/geno.1994.1013. PMID   8188243.


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