isohexenylglutaconyl-CoA hydratase | |||||||||
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Identifiers | |||||||||
EC no. | 4.2.1.57 | ||||||||
CAS no. | 37290-84-9 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme isohexenylglutaconyl-CoA hydratase (EC 4.2.1.57) catalyzes the chemical reaction
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase [3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA-forming]. Other names in common use include 3-hydroxy-3-isohexenylglutaryl-CoA-hydrolase, isohexenylglutaconyl coenzyme A hydratase, β-isohexenylglutaconyl-CoA-hydratase, and 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase.
3-Hydroxy-3-methylglutaryl-CoA lyase is an enzyme (EC 4.1.3.4 that in human is encoded by the HMGCL gene located on chromosome 1. It is a key enzyme in ketogenesis. It is a ketogenic enzyme in the liver that catalyzes the formation of acetoacetate from HMG-CoA within the mitochondria. It also plays a prominent role in the catabolism of the amino acid leucine.
The enzyme 3-hydroxy-3-isohexenylglutaryl-CoA lyase catalyzes the chemical reaction
The enzyme aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) catalyzes the chemical reaction
In enzymology, a geranoyl-CoA carboxylase (EC 6.4.1.5) is an enzyme that catalyzes the chemical reaction
The enzyme 2-oxopent-4-enoate hydratase (EC 4.2.1.80) catalyzes the chemical reaction
The enzyme 3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA hydratase (EC 4.2.1.107) catalyzes the chemical reaction
The enzyme 4-oxalmesaconate hydratase (EC 4.2.1.83) catalyzes the chemical reaction
The enzyme acetylenecarboxylate hydratase (EC 4.2.1.27) catalyzes the chemical reaction
In enzymology, a crotonoyl-[acyl-carrier-protein] hydratase (EC 4.2.1.58) is an enzyme that catalyzes the chemical reaction
The enzyme cyclohexa-1,5-dienecarbonyl-CoA hydratase (EC 4.2.1.100) catalyzes the chemical reaction
The enzyme long-chain-enoyl-CoA hydratase (EC 4.2.1.74) catalyzes the chemical reaction
The enzyme oleate hydratase (EC 4.2.1.53) catalyzes the chemical reaction
The enzyme pyrazolylalanine synthase (EC 4.2.1.50) catalyzes the chemical reaction
In enzymology, a trans-feruloyl-CoA hydratase (EC 4.2.1.101) is an enzyme that catalyzes the chemical reaction
Enoyl-CoA hydratase 2 is an enzyme with systematic name (3R)-3-hydroxyacyl-CoA hydro-lyase. This enzyme catalyses the following chemical reaction on D-3-hydroxyacyl-CoA
Carotenoid 1,2-hydratase (EC 4.2.1.131, CrtC) is an enzyme with systematic name lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming). This enzyme catalyses the following chemical reaction
2-hydroxyhexa-2,4-dienoate hydratase (EC 4.2.1.132, tesE (gene), hsaE (gene)) is an enzyme with systematic name 4-hydroxy-2-oxohexanoate hydro-lyase ((2Z,4Z)-2-hydroxyhexa-2,4-dienoate-forming). This enzyme catalyses the following chemical reaction
Copal-8-ol diphosphate hydratase (EC 4.2.1.133, CcCLS) is an enzyme with systematic name geranylgeranyl-diphosphate hydro-lyase ((13E)-8α-hydroxylabda-13-en-15-yl diphosphate forming). This enzyme catalyses the following chemical reaction