KIAA0409

RRP8
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2ZFU
Identifiers
Aliases	RRP8 , KIAA0409, NML, ribosomal RNA processing 8, methyltransferase, homolog (yeast), ribosomal RNA processing 8
External IDs	OMIM: 615818 MGI: 1914251 HomoloGene: 5621 GeneCards: RRP8
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p15.4 Start 6,595,072 bp [1] End 6,603,616 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 E3 Start 105,380,937 bp [2] End 105,386,592 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver popliteal artery left coronary artery body of stomach right coronary artery left lobe of thyroid gland body of pancreas left ventricle right lobe of thyroid gland ascending aorta Top expressed in primitive streak ureter secondary oocyte morula maxillary prominence yolk sac spermatocyte ascending aorta otic placode thymus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function methyltransferase activity transferase activity S-adenosylmethionine-dependent methyltransferase activity methylated histone binding protein binding RNA binding Cellular component plasma membrane nucleoplasm rDNA heterochromatin chromatin silencing complex nucleolus nucleus cytosol Biological process cellular response to glucose starvation regulation of transcription, DNA-templated regulation of transcription by glucose transcription, DNA-templated methylation rDNA heterochromatin assembly intrinsic apoptotic signaling pathway by p53 class mediator rRNA processing chromatin organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23378 101867 Ensembl ENSG00000132275 ENSMUSG00000030888 UniProt O43159 Q9DB85 RefSeq (mRNA) NM_015324 NM_025897 NM_133951 RefSeq (protein) NP_056139 NP_080173 NP_598712 Location (UCSC) Chr 11: 6.6 – 6.6 Mb Chr 7: 105.38 – 105.39 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Ribosomal RNA-processing protein 8 is a protein that in humans is encoded by the RRP8 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000132275 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000030888 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Ishikawa K, Nagase T, Nakajima D, Seki N, Ohira M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Feb 1998). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 4 (5): 307–13. doi: 10.1093/dnares/4.5.307 . PMID   9455477.
6. "Entrez Gene: KIAA0409 KIAA0409".

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID   16964243. S2CID   14294292.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi: 10.1073/pnas.0507066103 . PMC   1459365 . PMID   16565220.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC   133617 . PMID   12429849.
• Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi: 10.1016/S0960-9822(01)00650-9 . PMID   11790298. S2CID   14132033.

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Ribosomal RNA-processing protein 8 (KIAA0409)