KIAA1949

PPP1R18
Identifiers
Aliases	PPP1R18 , HKMT1098, KIAA1949, protein phosphatase 1 regulatory subunit 18
External IDs	OMIM: 610990 MGI: 1923698 HomoloGene: 19512 GeneCards: PPP1R18
Gene location (Human)
Chr.	Chromosome 6 (human)
End	30,687,895 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	36,186,488 bp
RNA expression pattern
	Top expressed in
	blood; ; lymph node; ; spleen; ; monocyte; ; appendix; ; right coronary artery; ; ascending aorta; ; bone marrow; ; gallbladder; ; bone marrow cells;
	Top expressed in
	thymus; ; blood; ; spleen; ; subcutaneous adipose tissue; ; external carotid artery; ; calvaria; ; internal carotid artery; ; entorhinal cortex; ; ascending aorta; ; white adipose tissue;
	More reference expression data
	n/a
Orthologs
	170954
	76448
ENSG00000229998 ; ENSG00000230341 ; ENSG00000225060 ; ENSG00000236428 ; ENSG00000146112 ;
	ENSG00000206485 ; ENSG00000231247 ; ENSG00000234000
	ENSMUSG00000034595
	Q6NYC8
	Q8BQ30
	NM_001134870 ; NM_133471
	NM_001146710 ; NM_001146711 ; NM_175242 ; NM_001378889
	NP_001128342 ; NP_597728
	NP_001140182 ; NP_001140183 ; NP_780451 ; NP_001365818
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated January 15, 2024

Phostensin is a protein that in humans is encoded by the KIAA1949 gene.^[5]^[6]

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References

1 2 3 ENSG00000230341, ENSG00000225060, ENSG00000236428, ENSG00000146112, ENSG00000206485, ENSG00000231247, ENSG00000234000 GRCh38: Ensembl release 89: ENSG00000229998, ENSG00000230341, ENSG00000225060, ENSG00000236428, ENSG00000146112, ENSG00000206485, ENSG00000231247, ENSG00000234000 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000034595 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Nagase T, Kikuno R, Ohara O (Feb 2002). "Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins". DNA Res. 8 (6): 319–27. doi:10.1093/dnares/8.6.319. PMID 11853319.
↑ "Entrez Gene: KIAA1949 KIAA1949".

Kao SC, Chen CY, Wang SL, et al. (2007). "Identification of phostensin, a PP1 F-actin cytoskeleton targeting subunit". Biochem. Biophys. Res. Commun. 356 (3): 594–8. doi:10.1016/j.bbrc.2007.03.026. PMID 17374523.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID 17081983. S2CID 7827573.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC 514446 . PMID 15302935.
Yamada S, Ohira M, Horie H, et al. (2004). "Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas". Oncogene. 23 (35): 5901–11. doi:10.1038/sj.onc.1207782. PMID 15221005. S2CID 3114318.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.

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[refGRCh38Ensembl-1] 1 2 3 ENSG00000230341, ENSG00000225060, ENSG00000236428, ENSG00000146112, ENSG00000206485, ENSG00000231247, ENSG00000234000 GRCh38: Ensembl release 89: ENSG00000229998, ENSG00000230341, ENSG00000225060, ENSG00000236428, ENSG00000146112, ENSG00000206485, ENSG00000231247, ENSG00000234000 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000034595 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11853319-5] Nagase T, Kikuno R, Ohara O (Feb 2002). "Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins". DNA Res. 8 (6): 319–27. doi:10.1093/dnares/8.6.319. PMID 11853319.

[entrez-6] "Entrez Gene: KIAA1949 KIAA1949".

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[2]

[3]

[4]

[5]

[6]

KIAA1949

Related Research Articles

References

Further reading