KIAA0368

ECPAS
Identifiers
Aliases	ECPAS , ECM29, Ecm29 proteasome adaptor and scaffold, KIAA0368
External IDs	OMIM: 616694; MGI: 2140220; HomoloGene: 6056; GeneCards: ECPAS; OMA:ECPAS - orthologs
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q31.3 Start 111,360,685 bp [1] End 111,484,745 bp [1]
Gene location (Mouse) Chr. Chromosome 4 (mouse) [2] Band 4|4 B3 Start 58,798,911 bp [2] End 58,912,749 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastrocnemius muscle tendon of biceps brachii buccal mucosa cell muscle of thigh glutes Skeletal muscle tissue of rectus abdominis Skeletal muscle tissue of biceps brachii deltoid muscle internal globus pallidus endothelial cell Top expressed in muscle of thigh plantaris muscle aortic valve extensor digitorum longus muscle secondary oocyte zygote cardiac muscle tissue of left ventricle primary oocyte ascending aorta quadriceps femoris muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding molecular adaptor activity proteasome binding Cellular component cytoplasm multivesicular body endosome late endosome centrosome membrane endocytic vesicle microtubule organizing center trans-Golgi network early endosome endoplasmic reticulum proteasome complex COPII-coated ER to Golgi transport vesicle cytoskeleton nucleus endoplasmic reticulum-Golgi intermediate compartment cytoplasmic vesicle Biological process ubiquitin-dependent ERAD pathway proteasome assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23392 230249 Ensembl ENSG00000136813 ENSMUSG00000050812 UniProt Q5VYK3 Q6PDI5 RefSeq (mRNA) NM_001080398 NM_001363756 NM_001364929 NM_001364930 NM_001364931 NM_172381 NM_001355696 NM_001355697 RefSeq (protein) NP_001073867 NP_001350685 NP_001351858 NP_001351859 NP_001351860 NP_759013 NP_001342625 NP_001342626 Location (UCSC) Chr 9: 111.36 – 111.48 Mb Chr 4: 58.8 – 58.91 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Proteasome-associated protein ECM29 homolog is a protein that in humans is encoded by the KIAA0368 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000136813 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000050812 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Sep 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 4 (2): 141–50. doi: 10.1093/dnares/4.2.141 . PMID   9205841.
6. Gorbea C, Goellner GM, Teter K, Holmes RK, Rechsteiner M (Dec 2004). "Characterization of mammalian Ecm29, a 26 S proteasome-associated protein that localizes to the nucleus and membrane vesicles". J Biol Chem. 279 (52): 54849–61. doi: 10.1074/jbc.M410444200 . PMID   15496406.
7. "Entrez Gene: KIAA0368 KIAA0368".

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID   8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC   139146 . PMID   9110174.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID   14743216. S2CID   11683986.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC   2734081 . PMID   15164053.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC   514446 . PMID   15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC   1847948 . PMID   17353931.