KIAA0430

MARF1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2DGX, 2DIU
Identifiers
Aliases	MARF1 , LKAP, PPP1R34, KIAA0430, LMKB, meiosis regulator and mRNA stability factor 1
External IDs	OMIM: 614593; MGI: 2444505; HomoloGene: 40967; GeneCards: MARF1; OMA:MARF1 - orthologs
Gene location (Human) Chr. Chromosome 16 (human) [1] Band 16p13.11 Start 15,594,387 bp [1] End 15,643,154 bp [1]
Gene location (Mouse) Chr. Chromosome 16 (mouse) [2] Band 16|16 A1 Start 13,927,037 bp [2] End 13,981,215 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in epithelium of colon bone marrow cells blood tonsil superior frontal gyrus monocyte dorsolateral prefrontal cortex Brodmann area 9 gastric mucosa anterior cingulate cortex Top expressed in zygote aortic valve ascending aorta supraoptic nucleus medial vestibular nucleus mammillary body lateral septal nucleus Rostral migratory stream interventricular septum ventromedial nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function RNA binding nucleic acid binding molecular function Cellular component peroxisome membrane Golgi apparatus intracellular membrane-bounded organelle Biological process negative regulation of phosphatase activity regulation of gene expression cell differentiation meiosis female meiotic nuclear division double-strand break repair oogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9665 223989 Ensembl ENSG00000166783 ENSG00000277140 ENSMUSG00000060657 UniProt Q9Y4F3 Q8BJ34 RefSeq (mRNA) NM_001184998 NM_001184999 NM_014647 NM_019081 NM_001081154 RefSeq (protein) NP_001171927 NP_001171928 NP_055462 NP_001074623 Location (UCSC) Chr 16: 15.59 – 15.64 Mb Chr 16: 13.93 – 13.98 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Limkain-b1 is a protein that in humans is encoded by the KIAA0430 gene. ^{[5] [6] [7] [8]}

References

1. ENSG00000277140 GRCh38: Ensembl release 89: ENSG00000166783, ENSG00000277140 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000060657 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Ishikawa K, Nagase T, Nakajima D, Seki N, Ohira M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Feb 1998). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 4 (5): 307–313. doi: 10.1093/dnares/4.5.307 . PMID   9455477.
6. Loftus BJ, Kim UJ, Sneddon VP, Kalush F, Brandon R, Fuhrmann J, Mason T, Crosby ML, Barnstead M, Cronin L, Deslattes Mays A, Cao Y, Xu RX, Kang HL, Mitchell S, Eichler EE, Harris PC, Venter JC, Adams MD (Nov 1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics. 60 (3): 295–308. doi:10.1006/geno.1999.5927. PMID   10493829.
7. Dunster K, Lai FP, Sentry JW (Jun 2005). "Limkain b1, a novel human autoantigen localized to a subset of ABCD3 and PXF marked peroxisomes". Clin Exp Immunol. 140 (3): 556–563. doi:10.1111/j.1365-2249.2005.02774.x. PMC   1809386 . PMID   15932519.
8. "Entrez Gene: KIAA0430 KIAA0430".

Further reading

• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID   8889548.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi: 10.1038/ng1285 . PMID   14702039.
• Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–716. doi:10.1038/nbt971. PMID   15146197. S2CID   27764390.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Martin J, Han C, Gordon LA, et al. (2005). "The sequence and analysis of duplication-rich human chromosome 16". Nature. 432 (7020): 988–994. Bibcode:2004Natur.432..988M. doi: 10.1038/nature03187 . PMID   15616553.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–648. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Meiosis regulator and mRNA stability factor 1 (KIAA0430)