KIAA1219

RALGAPB
Identifiers
Aliases	RALGAPB , KIAA1219, RalGAPbeta, Ral GTPase activating protein non-catalytic beta subunit, Ral GTPase activating protein non-catalytic subunit beta
External IDs	MGI: 2444531; HomoloGene: 10666; GeneCards: RALGAPB; OMA:RALGAPB - orthologs
Gene location (Human) Chr. Chromosome 20 (human) [1] Band 20q11.23 Start 38,472,816 bp [1] End 38,578,859 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 H1 Start 158,251,768 bp [2] End 158,341,173 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in buccal mucosa cell sperm endothelial cell secondary oocyte middle temporal gyrus seminal vesicula skin of thigh Brodmann area 23 visceral pleura corpus epididymis Top expressed in substantia nigra otolith organ secondary oocyte utricle fossa condyle hand epithelium of lens facial motor nucleus primary oocyte More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 57148 228850 Ensembl ENSG00000170471 ENSMUSG00000027652 UniProt Q86X10 Q8BQZ4 RefSeq (mRNA) NM_001282917 NM_001282918 NM_020336 NM_001291137 NM_001291138 NM_177227 NM_177658 NM_001363006 NM_001369183 RefSeq (protein) NP_001269846 NP_001269847 NP_065069 n/a Location (UCSC) Chr 20: 38.47 – 38.58 Mb Chr 2: 158.25 – 158.34 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

rotein KIAA1219 is a protein that in humans is encoded by the RALGAPB gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000170471 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000027652 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Shirakawa R, Fukai S, Kawato M, Higashi T, Kondo H, Ikeda T, Nakayama E, Okawa K, Nureki O, Kimura T, Kita T, Horiuchi H (Aug 2009). "Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases". J Biol Chem. 284 (32): 21580–8. doi: 10.1074/jbc.M109.012112 . PMC   2755882 . PMID   19520869.
6. "Entrez Gene: KIAA1219 KIAA1219".

Further reading

• Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi: 10.1093/dnares/9.3.99 . PMID   12168954.
• Gridley S, Chavez JA, Lane WS, Lienhard GE (2006). "Adipocytes contain a novel complex similar to the tuberous sclerosis complex". Cell. Signal. 18 (10): 1626–32. doi:10.1016/j.cellsig.2006.01.002. PMID   16490346.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC   514446 . PMID   15302935.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi: 10.1038/414865a . PMID   11780052.
• Nagase T, Ishikawa K, Kikuno R, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (5): 337–45. doi: 10.1093/dnares/6.5.337 . PMID   10574462.