KIAA0460

RPRD2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4FLB
Identifiers
Aliases	RPRD2 , KIAA0460, HSPC099, regulation of nuclear pre-mRNA domain containing 2
External IDs	OMIM: 614695 MGI: 1922387 HomoloGene: 19997 GeneCards: RPRD2
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q21.2 Start 150,363,091 bp [1] End 150,476,566 bp [1]
Gene location (Mouse) Chr. Chromosome 3 (mouse) [2] Band 3|3 F2.1 Start 95,667,653 bp [2] End 95,726,175 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in superficial temporal artery oocyte olfactory bulb thoracic diaphragm nipple endothelial cell renal medulla cardia germinal epithelium pylorus Top expressed in secondary oocyte cumulus cell atrioventricular valve endocardial cushion primitive streak trigeminal ganglion ureter pineal gland spermatocyte aortic valve More reference expression data BioGPS n/a
Gene ontology Molecular function RNA polymerase II complex binding Cellular component RNA polymerase II, holoenzyme nucleoplasm Biological process snRNA transcription by RNA polymerase II mRNA 3'-end processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23248 75137 Ensembl ENSG00000163125 ENSMUSG00000028106 UniProt Q5VT52 Q6NXI6 RefSeq (mRNA) NM_001297673 NM_001297674 NM_015203 NM_001081293 NM_028328 NM_029180 NM_001368178 NM_001368179 NM_001368180 NM_001368181 RefSeq (protein) NP_001284602 NP_001284603 NP_056018 NP_001074762 NP_001355107 NP_001355108 NP_001355109 NP_001355110 NP_082604 Location (UCSC) Chr 1: 150.36 – 150.48 Mb Chr 3: 95.67 – 95.73 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Regulation of nuclear pre-mRNA domain-containing protein 2 is a protein that in humans is encoded by the RPRD2 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000163125 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000028106 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Seki N, Ohira M, Nagase T, Ishikawa K, Miyajima N, Nakajima D, Nomura N, Ohara O (Feb 1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain". DNA Res. 4 (5): 345–9. doi: 10.1093/dnares/4.5.345 . PMID   9455484.
6. "Entrez Gene: KIAA0460 KIAA0460".

Further reading

• Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi: 10.1093/dnares/9.3.99 . PMID   12168954.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Lehner B, Sanderson CM (2004). "A Protein Interaction Framework for Human mRNA Degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC   442147 . PMID   15231747.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID   16710414.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID   16964243. S2CID   14294292.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Regulation of nuclear pre-mRNA domain-containing protein 2 (KIAA0460)