KIAA1012

TRAPPC8
Identifiers
Aliases	TRAPPC8 , GSG1, HsT2706, KIAA1012, TRS85, trafficking protein particle complex 8, trafficking protein particle complex subunit 8
External IDs	OMIM: 614136; MGI: 2443008; HomoloGene: 40993; GeneCards: TRAPPC8; OMA:TRAPPC8 - orthologs
Gene location (Human)
Chr.	Chromosome 18 (human)
End	31,953,136 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	21,029,150 bp
RNA expression pattern
	Top expressed in
	hair follicle; ; gonad; ; jejunal mucosa; ; caput epididymis; ; sperm; ; superior surface of tongue; ; renal medulla; ; cardia; ; bronchial epithelial cell; ; corpus epididymis;
	Top expressed in
	superior cervical ganglion; ; otolith organ; ; utricle; ; hand; ; retinal pigment epithelium; ; skin of abdomen; ; primary oocyte; ; ciliary body; ; cumulus cell; ; transitional epithelium of urinary bladder;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding ;
Cellular component	phagophore assembly site ; cytoplasmic vesicle ; TRAPPIII protein complex ; Golgi apparatus ; cytosol ; TRAPP complex ;
Biological process	protein localization to phagophore assembly site ; autophagy of peroxisome ; cytoplasm to vacuole transport by the Cvt pathway ; autophagy of nucleus ; endoplasmic reticulum to Golgi vesicle-mediated transport ; vesicle-mediated transport ; Golgi organization ; autophagosome assembly ;
	Sources:Amigo / QuickGO
Orthologs
	22878
	75964
	ENSG00000153339
	ENSMUSG00000033382
	Q9Y2L5
	n/a
	NM_014939
	NM_029491 ; NM_177038 ; NM_001361188 ; NM_001379370
	NP_055754
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated December 19, 2025

Protein TRS85 homolog is a protein that in humans is encoded by the KIAA1012 gene.^[5]^[6]^[7]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000153339 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000033382 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jul 1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi: 10.1093/dnares/6.1.63 . PMID 10231032.
↑ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
↑ "Entrez Gene: KIAA1012 KIAA1012".

Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129 . PMID 16344560.
Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11): 1093–101. doi: 10.1074/mcp.M400085-MCP200 . PMID 15345747.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Gavin AC, Bösche M, Krause R, et al. (2002). "Functional organization of the yeast proteome by systematic analysis of protein complexes". Nature. 415 (6868): 141–7. Bibcode:2002Natur.415..141G. doi:10.1038/415141a. PMID 11805826. S2CID 4425555.
Sacher M, Barrowman J, Schieltz D, et al. (2000). "Identification and characterization of five new subunits of TRAPP". Eur. J. Cell Biol. 79 (2): 71–80. doi: 10.1078/S0171-9335(04)70009-6 . PMID 10727015.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000153339 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000033382 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10231032-5] Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jul 1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi: 10.1093/dnares/6.1.63 . PMID 10231032.

[pmid11230166-6] Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.

[entrez-7] "Entrez Gene: KIAA1012 KIAA1012".

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KIAA1012

References

Further reading